5TR7
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![BU of 5tr7 by Molmil](/molmil-images/mine/5tr7) | Crystal structure of a putative D-alanyl-D-alanine carboxypeptidase from Vibrio cholerae O1 biovar eltor str. N16961 | 分子名称: | D-alanyl-D-alanine carboxypeptidase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Shatsman, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-10-25 | 公開日 | 2016-11-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of a putative D-alanyl-D-alanine carboxypeptidase from Vibrio cholerae O1 biovar eltor str. N16961 To Be Published
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5T7O
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![BU of 5t7o by Molmil](/molmil-images/mine/5t7o) | Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase in complex with (6S)-5,6,7,8-TETRAHYDROFOLATE | 分子名称: | (6S)-5,6,7,8-TETRAHYDROFOLATE, 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ... | 著者 | Di Pisa, F, Dello Iacono, L, Bonucci, A, Mangani, S. | 登録日 | 2016-09-05 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase in complex with (6S)-5,6,7,8-TETRAHYDROFOLATE To Be Published
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5TK4
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![BU of 5tk4 by Molmil](/molmil-images/mine/5tk4) | Crystal Structure of Uncharacterized Cupredoxin-like Domain Protein from Bacillus anthracis | 分子名称: | Cytochrome B | 著者 | Kim, Y, Maltseva, N, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-10-06 | 公開日 | 2016-11-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Crystal Structure of Uncharacterized Cupredoxin-like Domain Protein from
Bacillus anthracis To Be Published
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5V9X
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![BU of 5v9x by Molmil](/molmil-images/mine/5v9x) | Structure of Mycobacterium smegmatis helicase Lhr bound to ssDNA and AMP-PNP | 分子名称: | ATP-dependent DNA helicase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Ordonez, H, Jacewicz, A, Ferrao, R, Shuman, S. | 登録日 | 2017-03-23 | 公開日 | 2017-12-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.797 Å) | 主引用文献 | Structure of mycobacterial 3'-to-5' RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases. Nucleic Acids Res., 46, 2018
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5TK2
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![BU of 5tk2 by Molmil](/molmil-images/mine/5tk2) | Crystal Structure of Uncharacterized Cupredoxin-like domain protein from Bacillus anthracis | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, Cytochrome B, ... | 著者 | Kim, Y, Maltseva, N, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-10-06 | 公開日 | 2016-11-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal Structure of Uncharacterized Cupredoxin-like domain protein from
Bacillus anthracis To Be Published
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5W3F
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![BU of 5w3f by Molmil](/molmil-images/mine/5w3f) | Yeast tubulin polymerized with GTP in vitro | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Howes, S.C, Geyer, E.A, LaFrance, B, Zhang, R, Kellogg, E.H, Westermann, S, Rice, L.M, Nogales, E. | 登録日 | 2017-06-07 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural differences between yeast and mammalian microtubules revealed by cryo-EM. J. Cell Biol., 216, 2017
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5W3H
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![BU of 5w3h by Molmil](/molmil-images/mine/5w3h) | Yeast microtubule stabilized with epothilone | 分子名称: | EPOTHILONE A, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Howes, S.C, Geyer, E.A, LaFrance, B, Zhang, R, Kellogg, E.H, Westermann, S, Rice, L.M, Nogales, E. | 登録日 | 2017-06-07 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural differences between yeast and mammalian microtubules revealed by cryo-EM. J. Cell Biol., 216, 2017
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4ZTD
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![BU of 4ztd by Molmil](/molmil-images/mine/4ztd) | Crystal Structure of Human PCNA in complex with a TRAIP peptide | 分子名称: | ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen | 著者 | Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A. | 登録日 | 2015-05-14 | 公開日 | 2015-12-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress. J.Cell Biol., 212, 2016
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7DPI
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![BU of 7dpi by Molmil](/molmil-images/mine/7dpi) | Plasmodium falciparum cytoplasmic Phenylalanyl-tRNA synthetase in complex with BRD7929 | 分子名称: | (8R,9S,10S)-10-[(dimethylamino)methyl]-N-(4-methoxyphenyl)-9-[4-(2-phenylethynyl)phenyl]-1,6-diazabicyclo[6.2.0]decane-6-carboxamide, MAGNESIUM ION, Phenylalanine--tRNA ligase, ... | 著者 | Manmohan, S, Malhotra, N, Harlos, K, Manickam, Y, Sharma, A. | 登録日 | 2020-12-19 | 公開日 | 2022-03-23 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.597 Å) | 主引用文献 | Inhibition of Plasmodium falciparum phenylalanine tRNA synthetase provides opportunity for antimalarial drug development. Structure, 30, 2022
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2GU1
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![BU of 2gu1 by Molmil](/molmil-images/mine/2gu1) | Crystal structure of a zinc containing peptidase from vibrio cholerae | 分子名称: | SODIUM ION, ZINC ION, Zinc peptidase | 著者 | Sugadev, R, Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2006-04-28 | 公開日 | 2006-07-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of a putative lysostaphin peptidase from Vibrio cholerae. Proteins, 72, 2008
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9FCH
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![BU of 9fch by Molmil](/molmil-images/mine/9fch) | |
1YYN
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![BU of 1yyn by Molmil](/molmil-images/mine/1yyn) | A common binding site for disialyllactose and a tri-peptide in the C-fragment of tetanus neurotoxin | 分子名称: | N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-3)-alpha-D-galactopyranose-(1-4)-beta-D-glucopyranose, Tetanus toxin | 著者 | Seetharaman, J, Eswaramoorthy, S, Kumaran, D, Swaminathan, S. | 登録日 | 2005-02-25 | 公開日 | 2005-03-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Common binding site for disialyllactose and tri-peptide in C-fragment of tetanus neurotoxin Proteins, 61, 2005
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3C0K
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![BU of 3c0k by Molmil](/molmil-images/mine/3c0k) | |
3QBN
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![BU of 3qbn by Molmil](/molmil-images/mine/3qbn) | |
2M59
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![BU of 2m59 by Molmil](/molmil-images/mine/2m59) | |
2MET
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![BU of 2met by Molmil](/molmil-images/mine/2met) | NMR spatial structure of the trimeric mutant TM domain of VEGFR2 receptor. | 分子名称: | Vascular endothelial growth factor receptor 2 | 著者 | Mineev, K.S, Arseniev, A.A, Shulepko, M, Lyukmanova, E.N, Kirpichnikov, M.P. | 登録日 | 2013-10-02 | 公開日 | 2014-07-30 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation Structure, 22, 2014
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2MEU
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![BU of 2meu by Molmil](/molmil-images/mine/2meu) | NMR spatial structure of mutant dimeric TM domain of VEGFR2 receptor | 分子名称: | Vascular endothelial growth factor receptor 2 | 著者 | Mineev, K.S, Arseniev, A.S, Lyukmanova, E.N, Shulepko, M.A, Kirpichnikov, M.P. | 登録日 | 2013-10-02 | 公開日 | 2014-07-30 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation Structure, 22, 2014
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6Z17
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![BU of 6z17 by Molmil](/molmil-images/mine/6z17) | PqsR (MvfR) in complex with antagonist 6 | 分子名称: | 6-chloranyl-3-[(2-propan-2-yl-2,3-dihydro-1,3-thiazol-4-yl)methyl]quinazolin-4-one, Transcriptional regulator MvfR | 著者 | Richardson, W.K, Emsley, J. | 登録日 | 2020-05-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur.J.Med.Chem., 208, 2020
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6YZ3
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![BU of 6yz3 by Molmil](/molmil-images/mine/6yz3) | PqsR (MvfR) in complex with antagonist 19 | 分子名称: | 1,2-ETHANEDIOL, 6-chloranyl-3-[(2-hexyl-2,3-dihydro-1,3-thiazol-4-yl)methyl]quinazolin-4-one, LysR family transcriptional regulator | 著者 | Richardson, W.K, Emsley, J. | 登録日 | 2020-05-06 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur.J.Med.Chem., 208, 2020
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6Z07
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![BU of 6z07 by Molmil](/molmil-images/mine/6z07) | PqsR (MvfR) in complex with antagonist 12 | 分子名称: | 3-[(2-~{tert}-butyl-1,3-thiazol-4-yl)methyl]-6-chloranyl-quinazolin-4-one, GLYCEROL, Transcriptional regulator MvfR | 著者 | Richardson, W.K, Emsley, J. | 登録日 | 2020-05-07 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur.J.Med.Chem., 208, 2020
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6Z5K
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![BU of 6z5k by Molmil](/molmil-images/mine/6z5k) | PqsR (MvfR) in complex with antagonist 18 | 分子名称: | 6-chloranyl-3-[(2-pentyl-2,3-dihydro-1,3-thiazol-4-yl)methyl]quinazolin-4-one, Transcriptional regulator MvfR | 著者 | Richardson, W.K, Emsley, J. | 登録日 | 2020-05-26 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | 主引用文献 | Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur.J.Med.Chem., 208, 2020
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6KJL
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![BU of 6kjl by Molmil](/molmil-images/mine/6kjl) | Xylanase J from Bacillus sp. strain 41M-1 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Manami, S, Teisuke, T, Nakatani, K, Katano, K, Kojima, K, Saka, N, Mikami, B, Yatsunami, R, Nakamura, S, Yasukawa, K. | 登録日 | 2019-07-22 | 公開日 | 2019-09-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Increase in the thermostability of GH11 xylanase XynJ from Bacillus sp. strain 41M-1 using site saturation mutagenesis. Enzyme.Microb.Technol., 130, 2019
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2OUX
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![BU of 2oux by Molmil](/molmil-images/mine/2oux) | |
8GCY
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![BU of 8gcy by Molmil](/molmil-images/mine/8gcy) | Co-crystal structure of CBL-B in complex with N-Aryl isoindolin-1-one inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-{3-[(1s,3R)-3-methyl-1-(4-methyl-4H-1,2,4-triazol-3-yl)cyclobutyl]phenyl}-6-{[(3S)-3-methylpiperidin-1-yl]methyl}-4-(trifluoromethyl)-2,3-dihydro-1H-isoindol-1-one, E3 ubiquitin-protein ligase CBL-B, ... | 著者 | Kimani, S, Zeng, H, Dong, A, Li, Y, Santhakumar, V, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | 登録日 | 2023-03-03 | 公開日 | 2023-03-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition. Commun Biol, 6, 2023
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2KS6
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![BU of 2ks6 by Molmil](/molmil-images/mine/2ks6) | |