8U1R
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8TMA
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8U1G
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8TM1
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8TW3
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8V5K
| Structure of the Human Respirovirus 3 Fusion Protein Bound to Camelid Nanobodies 4C03 and 4C06 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Camelid Nanobody 4C03, Camelid Nanobody 4C06, ... | 著者 | Johnson, N.V, Ramamohan, A.R, McLellan, J.S. | 登録日 | 2023-11-30 | 公開日 | 2024-05-22 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies. Nat Commun, 15, 2024
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8V62
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5W24
| Crystal Structure of 5C4 Fab | 分子名称: | (R,R)-2,3-BUTANEDIOL, 5C4 Fab Heavy Chain, 5C4 Fab Light Chain | 著者 | Battles, M.B, McLellan, J.S, Taher, N.M. | 登録日 | 2017-06-05 | 公開日 | 2017-12-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein. Nat Commun, 8, 2017
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8TCO
| HCMV Trimer in complex with CS2it1p2_F7K Fab and CS4tt1p1_E3K Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CS2it1p2_F7K Fab heavy chain, ... | 著者 | Goldsmith, J.A, McLellan, J.S. | 登録日 | 2023-07-02 | 公開日 | 2023-08-09 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer. Immunity, 56, 2023
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8TEA
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7L3N
| SARS-CoV 2 Spike Protein bound to LY-CoV555 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LY-CoV555 Fab heavy chain, ... | 著者 | Goldsmith, J.A, McLellan, J.S. | 登録日 | 2020-12-18 | 公開日 | 2021-02-03 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection. Biorxiv, 2020
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7KX4
| Anti-CCHFV ADI-36121 Fab | 分子名称: | ADI-36121 Fab heavy chain, ADI-36121 Fab light chain | 著者 | Mishra, A.K, McLellan, J.S. | 登録日 | 2020-12-03 | 公開日 | 2021-12-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies. Science, 375, 2022
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7LVW
| Structure of RSV F in Complex with VHH Cl184 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, F-VHH-Cl184, ... | 著者 | Hsieh, C.-L, McLellan, J.S. | 登録日 | 2021-02-26 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody. J.Virol., 95, 2021
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7LVU
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7LYV
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7LYW
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7M8J
| SARS-CoV-2 S-NTD + Fab CM25 | 分子名称: | CM25 Fab - Heavy Chain, CM25 Fab - Light Chain, Spike protein S1 | 著者 | Johnson, N.V, Mclellan, J.S. | 登録日 | 2021-03-29 | 公開日 | 2021-05-19 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes. Science, 372, 2021
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7L7R
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7LUE
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7LUD
| Crystal structure of Fab ADI-14442 | 分子名称: | ADI-14442 Fab Heavy chain, ADI-14442 Fab Light chain, SULFATE ION | 著者 | Rush, S.A, McLellan, J.S. | 登録日 | 2021-02-22 | 公開日 | 2021-06-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021
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7M1C
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7M30
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7M22
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7LUC
| Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B | 分子名称: | 01.4B Fab Heavy chain, 01.4B Fab Light chain, 32.4K Fab Heavy chain, ... | 著者 | Wrapp, D, McLellan, J.S. | 登録日 | 2021-02-22 | 公開日 | 2021-04-21 | 最終更新日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021
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5EA6
| Crystal Structure of Inhibitor BTA-9881 in Complex with Prefusion RSV F Glycoprotein | 分子名称: | (9~{b}~{R})-9~{b}-(4-chlorophenyl)-1-pyridin-3-ylcarbonyl-2,3-dihydroimidazo[5,6]pyrrolo[1,2-~{a}]pyridin-5-one, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Fusion glycoprotein F0, ... | 著者 | Battles, M.B, McLellan, J.S, Arnoult, E, Roymans, D, Langedijk, J.P. | 登録日 | 2015-10-15 | 公開日 | 2015-12-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Molecular mechanism of respiratory syncytial virus fusion inhibitors. Nat.Chem.Biol., 12, 2016
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