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5CYU
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BU of 5cyu by Molmil
Structure of the soluble domain of EccB1 from the Mycobacterium smegmatis ESX-1 secretion system.
分子名称: Conserved membrane protein
著者Arbing, M.A, Chan, S, Kahng, S, Kim, J, Eisenberg, D.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-07-30
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system.
Bmc Struct.Biol., 16, 2016
5DLB
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BU of 5dlb by Molmil
Crystal structure of chaperone EspG3 of ESX-3 type VII secretion system from Mycobacterium marinum M
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, PLATINUM (II) ION, ...
著者Chan, S, Arbing, M.A, Kim, J, Kahng, S, Sawaya, M.R, Eisenberg, D.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-09-04
公開日2015-09-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
4M5T
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BU of 4m5t by Molmil
Disulfide trapped human alphaB crystallin core domain in complex with C-terminal peptide
分子名称: Alpha-crystallin B chain, SULFATE ION
著者Laganowsky, A, Cascio, D, Hochberg, G, Sawaya, M.R, Benesch, J.L.P, Robinson, C.V, Eisenberg, D.
登録日2013-08-08
公開日2014-04-09
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MJH
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BU of 4mjh by Molmil
Human Hsp27 core domain in complex with C-terminal peptide
分子名称: Heat shock protein beta-1
著者Laganowsky, A, Cascio, D, Sawaya, M.R, Eisenberg, D.
登録日2013-09-03
公開日2014-04-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NIP
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BU of 4nip by Molmil
GVIGIAQ segment 147-153 from Human Superoxide Dismutase
分子名称: GVTGIAQ segment from Superoxide dismutase [Cu-Zn]
著者Sievers, S.A, Sawaya, M.R, Eisenberg, D, Ivanova, M.I.
登録日2013-11-06
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Proc.Natl.Acad.Sci.USA, 111, 2014
3G5O
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BU of 3g5o by Molmil
The crystal structure of the toxin-antitoxin complex RelBE2 (Rv2865-2866) from Mycobacterium tuberculosis
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
著者Miallau, L, Cascio, D, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
登録日2009-02-05
公開日2009-04-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Comparative proteomics identifies the cell-associated lethality of M. tuberculosis RelBE-like toxin-antitoxin complexes.
Structure, 21, 2013
4M5S
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BU of 4m5s by Molmil
Human alphaB crystallin core domain in complex with C-terminal peptide
分子名称: Alpha-crystallin B chain, SUCCINIC ACID
著者Laganowsky, A, Cascio, D, Sawaya, M.R, Eisenberg, D.
登録日2013-08-08
公開日2014-04-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NIN
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BU of 4nin by Molmil
DSVISLS segment 101-107 from Human Superoxide Dismutase
分子名称: DSVISLS segment from Superoxide dismutase [Cu-Zn], ZINC ION
著者Sievers, S.A, Sawaya, M.R, Eisenberg, D.
登録日2013-11-06
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NIO
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BU of 4nio by Molmil
GVTGIAQ segment 147-153 from Human Superoxide Dismutase with I149T mutation associated with a familial form of amyotrophic lateral sclerosis
分子名称: GVTGIAQ segment from Superoxide dismutase [Cu-Zn]
著者Sievers, S.A, Sawaya, M.R, Eisenberg, D, Ivanova, M.I.
登録日2013-11-06
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Proc.Natl.Acad.Sci.USA, 111, 2014
7N8R
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BU of 7n8r by Molmil
FGTGFG segment from the Nucleoporin p54, residues 63-68
分子名称: FGTGFG segment from the Nucleoporin p54, residues 63-68, trifluoroacetic acid
著者Hughes, M.P, Sawaya, M.R, Eisenberg, D.S.
登録日2021-06-15
公開日2022-02-16
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Extended beta-Strands Contribute to Reversible Amyloid Formation.
Acs Nano, 16, 2022
3OEI
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BU of 3oei by Molmil
Crystal structure of Mycobacterium tuberculosis RelJK (Rv3357-Rv3358-RelBE3)
分子名称: CITRATE ANION, RelJ (Antitoxin Rv3357), RelK (Toxin Rv3358)
著者Miallau, L, Cascio, D, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2010-08-12
公開日2011-03-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.145 Å)
主引用文献Comparative proteomics identifies the cell-associated lethality of M. tuberculosis RelBE-like toxin-antitoxin complexes.
Structure, 21, 2013
6UUR
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BU of 6uur by Molmil
Human prion protein fibril, M129 variant
分子名称: Major prion protein
著者Glynn, C, Sawaya, M.R, Ge, P, Zhou, Z.H, Rodriguez, J.A.
登録日2019-10-31
公開日2020-04-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.
Nat.Struct.Mol.Biol., 27, 2020
1I8F
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BU of 1i8f by Molmil
THE CRYSTAL STRUCTURE OF A HEPTAMERIC ARCHAEAL SM PROTEIN: IMPLICATIONS FOR THE EUKARYOTIC SNRNP CORE
分子名称: GLYCEROL, PUTATIVE SNRNP SM-LIKE PROTEIN
著者Mura, C, Cascio, D, Sawaya, M.R, Eisenberg, D.
登録日2001-03-14
公開日2001-05-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP core.
Proc.Natl.Acad.Sci.USA, 98, 2001
4ONK
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BU of 4onk by Molmil
[Leu-5]-Enkephalin mutant - YVVFL
分子名称: [Leu-5]-Enkephalin mutant - YVVFL
著者Sangwan, S, Eisenberg, D, Sawaya, M.R, Do, T.D, Bowers, M.T, Lapointe, N.E, Teplow, D.B, Feinstein, S.C.
登録日2014-01-28
公開日2014-07-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants.
J.Phys.Chem.B, 118, 2014
4OLR
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BU of 4olr by Molmil
[Leu-5]-Enkephalin mutant - YVVFV
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, [Leu-5]-Enkephalin mutant - YVVFV
著者Sangwan, S, Eisenberg, D, Sawaya, M.R, Do, T.D, Bowers, M.T, Lapointe, N.E, Teplow, D.B, Feinstein, S.C.
登録日2014-01-24
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants.
J.Phys.Chem.B, 118, 2014
4QXX
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BU of 4qxx by Molmil
Structure of the amyloid forming peptide GNLVS (residues 26-30) from the eosinophil major basic protein (EMBP)
分子名称: Bone marrow proteoglycan
著者Soriaga, A.B, Soragni, A, Sawaya, M.R, Eisenberg, D.
登録日2014-07-22
公開日2015-03-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.445 Å)
主引用文献Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation.
Mol.Cell, 57, 2015
4QX1
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BU of 4qx1 by Molmil
Cry3A Toxin structure obtained by Serial Femtosecond Crystallography from in vivo grown crystals isolated from Bacillus thuringiensis and data processed with the CrystFEL software suite
分子名称: Pesticidal crystal protein cry3Aa
著者Sawaya, M.R, Cascio, D, Gingery, M, Rodriguez, J, Goldschmidt, L, Colletier, J.-P, Messerschmidt, M, Boutet, S, Koglin, J.E, Williams, G.J, Brewster, A.S, Nass, K, Hattne, J, Botha, S, Doak, R.B, Shoeman, R.L, DePonte, D.P, Park, H.-W, Federici, B.A, Sauter, N.K, Schlichting, I, Eisenberg, D.
登録日2014-07-17
公開日2014-08-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
4QX2
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BU of 4qx2 by Molmil
Cry3A Toxin structure obtained by injecting Bacillus thuringiensis cells in an XFEL beam, collecting data by serial femtosecond crystallographic methods and processing data with the cctbx.xfel software suite
分子名称: Pesticidal crystal protein cry3Aa
著者Sawaya, M.R, Cascio, D, Gingery, M, Rodriguez, J, Goldschmidt, L, Colletier, J.-P, Messerschmidt, M, Boutet, S, Koglin, J.E, Williams, G.J, Brewster, A.S, Nass, K, Hattne, J, Botha, S, Doak, R.B, Shoeman, R.L, DePonte, D.P, Park, H.-W, Federici, B.A, Sauter, N.K, Schlichting, I, Eisenberg, D.
登録日2014-07-17
公開日2014-08-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
4QX3
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BU of 4qx3 by Molmil
Cry3A Toxin structure obtained by injecting Bacillus thuringiensis cells in an XFEL beam, collecting data by serial femtosecond crystallographic methods and processing data with the CrystFEL software suite
分子名称: Pesticidal crystal protein cry3Aa
著者Sawaya, M.R, Cascio, D, Gingery, M, Rodriguez, J, Goldschmidt, L, Colletier, J.-P, Messerschmidt, M, Boutet, S, Koglin, J.E, Williams, G.J, Brewster, A.S, Nass, K, Hattne, J, Botha, S, Doak, R.B, Shoeman, R.L, DePonte, D.P, Park, H.-W, Federici, B.A, Sauter, N.K, Schlichting, I, Eisenberg, D.
登録日2014-07-17
公開日2014-08-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
4QX0
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BU of 4qx0 by Molmil
Cry3A Toxin structure obtained by Serial Femtosecond Crystallography from in vivo grown crystals isolated from Bacillus thuringiensis and data processed with the cctbx.xfel software suite
分子名称: Pesticidal crystal protein cry3Aa
著者Sawaya, M.R, Cascio, D, Gingery, M, Rodriguez, J, Goldschmidt, L, Colletier, J.-P, Messerschmidt, M, Boutet, S, Koglin, J.E, Williams, G.J, Brewster, A.S, Nass, K, Hattne, J, Botha, S, Doak, R.B, Shoeman, R.L, DePonte, D.P, Park, H.-W, Federici, B.A, Sauter, N.K, Schlichting, I, Eisenberg, D.
登録日2014-07-17
公開日2014-08-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
4RP7
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BU of 4rp7 by Molmil
Structure of the amyloid-forming segment TIITLE from p53 (residues 253-258)
分子名称: TIITLE hexapeptide segment from p53, ZINC ION
著者Soriaga, A.B, Soragni, A, Eisenberg, D.
登録日2014-10-29
公開日2016-01-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.576 Å)
主引用文献A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Cancer Cell, 29, 2016
4RP6
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BU of 4rp6 by Molmil
Structure of the amyloid-forming segment LTIITLE from p53 (residues 252-258)
分子名称: LTIITLE heptapeptide segment from p53
著者Soriaga, A.B, Soragni, A, Eisenberg, D.
登録日2014-10-29
公開日2016-01-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.703 Å)
主引用文献A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Cancer Cell, 29, 2016
1A2W
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BU of 1a2w by Molmil
CRYSTAL STRUCTURE OF A 3D DOMAIN-SWAPPED DIMER OF BOVINE PANCREATIC RIBONUCLEASE A
分子名称: CHLORIDE ION, RIBONUCLEASE A, SULFATE ION
著者Liu, Y, Hart, P.J, Schlunegger, M.P, Eisenberg, D.S.
登録日1998-01-12
公開日1998-04-29
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of a 3D domain-swapped dimer of RNase A at a 2.1-A resolution.
Proc.Natl.Acad.Sci.USA, 95, 1998
1JCV
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BU of 1jcv by Molmil
REDUCED BRIDGE-BROKEN YEAST CU/ZN SUPEROXIDE DISMUTASE LOW TEMPERATURE (-180C) STRUCTURE
分子名称: COPPER (II) ION, CU/ZN SUPEROXIDE DISMUTASE, ZINC ION
著者Ogihara, N.L, Parge, H.E, Hart, P.J, Weiss, M.S, Valentine, J.S, Eisenberg, D.S, Tainer, J.A.
登録日1995-12-07
公開日1996-03-08
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Unusual trigonal-planar copper configuration revealed in the atomic structure of yeast copper-zinc superoxide dismutase.
Biochemistry, 35, 1996
8TDN
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BU of 8tdn by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient-3, wild-type morphology
分子名称: Transthyretin
著者Nguyen, B.A, Singh, V, Saelices, L.
登録日2023-07-04
公開日2023-12-13
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024

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