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6NK7
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Electron Cryo-Microscopy of Chikungunya in Complex with Mouse Mxra8 Receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
著者Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-04
公開日2019-05-22
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.99 Å)
主引用文献Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
6NXJ
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Flavin Transferase ApbE from Vibrio cholerae, H257G mutant
分子名称: FAD:protein FMN transferase, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION
著者Osipiuk, J, Fang, X, Chakravarthy, S, Juarez, O, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-02-08
公開日2019-03-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Conserved residue His-257 ofVibrio choleraeflavin transferase ApbE plays a critical role in substrate binding and catalysis.
J.Biol.Chem., 294, 2019
5UXA
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Crystal structure of macrolide 2'-phosphotransferase MphB from Escherichia coli
分子名称: CALCIUM ION, Macrolide 2'-phosphotransferase II
著者Stogios, P.J, Evdokimova, E, Egorova, O, Di Leo, R, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-22
公開日2017-06-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.
Nat Commun, 9, 2018
5USD
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Crystal structure of MccF-like protein (BA_5613) in the complex with aspartyl sulfamoyl adenylate
分子名称: 5'-O-(L-alpha-aspartylsulfamoyl)adenosine, GLYCEROL, Peptidase S66
著者Nocek, B, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-13
公開日2017-03-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.095 Å)
主引用文献Crystal structure of MccF-like protein (BA_5613) in the complex with aspartyl sulfamoyl adenylate
To Be Published
5USX
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Crystal structure of thioredoxin-disulfide reductase from Vibrio vulnificus CMCP6 in complex with NADP and FAD
分子名称: 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Chang, C, Grimshaw, S, Maltseva, N, Mulligan, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-14
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Crystal structure of thioredoxin-disulfide reductase from Vibrio vulnificus CMCP6 in complex with NADP and FAD
To Be Published
6NK6
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BU of 6nk6 by Molmil
Electron Cryo-Microscopy Of Chikungunya VLP in complex with mouse Mxra8 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
著者Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-04
公開日2019-05-22
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
6NOZ
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X-ray structure of PEDV papain-like protease 2
分子名称: GLYCEROL, Polyprotein, ZINC ION
著者Clasman, J.C, Mesecar, A.D, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-16
公開日2020-01-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Evaluating ubiquitin specificity of papain-like protease 2 from alphacoronaviruses FIPV and PEDV using structure-guided engineering
To Be Published
5UXD
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Crystal structure of macrolide 2'-phosphotransferase MphH from Brachybacterium faecium in complex with azithromycin
分子名称: AZITHROMYCIN, CHLORIDE ION, Macrolide 2'-phosphotransferase MphH, ...
著者Stogios, P.J, Skarina, T, Wawrzak, Z, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-22
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.
Nat Commun, 9, 2018
5UTT
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SrtA sortase from Actinomyces oris
分子名称: CHLORIDE ION, Sortase
著者Osipiuk, J, Ma, X, Ton-That, H, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-15
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Cell-to-cell interaction requires optimal positioning of a pilus tip adhesin modulated by gram-positive transpeptidase enzymes.
Proc.Natl.Acad.Sci.USA, 116, 2019
6MXV
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The crystal structure of a rhodanese-like family protein from Francisella tularensis subsp. tularensis SCHU S4
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DODECAETHYLENE GLYCOL, ...
著者Tan, K, Skarina, T, Di Leo, R, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-10-31
公開日2018-11-21
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献The crystal structure of a rhodanese-like family protein from Francisella tularensis subsp. tularensis SCHU S4
To Be Published
5UTX
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Crystal structure of thioredoxin-disulfide reductase from Vibrio vulnificus CMCP6 - apo form
分子名称: PHOSPHATE ION, Thioredoxin reductase
著者Chang, C, Grimshaw, S, Maltseva, N, Mulligan, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-15
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Crystal structure of thioredoxin-disulfide reductase from Vibrio vulnificus CMCP6 - apo form
To Be Published
5UU6
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BU of 5uu6 by Molmil
The crystal structure of nitroreductase A from Vibrio parahaemolyticus RIMD 2210633
分子名称: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Tan, K, Zhou, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-16
公開日2017-03-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The crystal structure of nitroreductase A from Vibrio parahaemolyticus RIMD 2210633
To Be Published
5UXC
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BU of 5uxc by Molmil
Crystal structure of macrolide 2'-phosphotransferase MphH from Brachybacterium faecium in complex with GDP
分子名称: AZITHROMYCIN, CHLORIDE ION, GLYCEROL, ...
著者Stogios, P.J, Skarina, T, Wawrzak, Z, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-22
公開日2017-08-16
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.
Nat Commun, 9, 2018
5US1
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BU of 5us1 by Molmil
Crystal structure of aminoglycoside acetyltransferase AAC(2')-Ia in complex with N2'-acetylgentamicin C1A and coenzyme A
分子名称: (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-(acetylamino)-6-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside, ACETYL COENZYME *A, Aminoglycoside 2'-N-acetyltransferase, ...
著者Stogios, P.J, Evdokimova, E, Xu, Z, Wawrzak, Z, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-13
公開日2017-03-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes.
ACS Infect Dis, 4, 2018
5UXB
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BU of 5uxb by Molmil
Crystal structure of macrolide 2'-phosphotransferase MphH from Brachybacterium faecium, apoenzyme
分子名称: CHLORIDE ION, Macrolide 2'-phosphotransferase MphH
著者Stogios, P.J, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-22
公開日2017-07-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.794 Å)
主引用文献The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.
Nat Commun, 9, 2018
5UX9
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BU of 5ux9 by Molmil
The crystal structure of chloramphenicol acetyltransferase from Vibrio fischeri ES114
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, CHLORIDE ION, ...
著者Tan, K, Zhou, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-22
公開日2017-03-08
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of chloramphenicol acetyltransferase from Vibrio fischeri ES114
To Be Published
5UC7
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BU of 5uc7 by Molmil
Crystal structure of BioA / 7,8-diaminopelargonic acid aminotransferase / DAPA synthase from Citrobacter rodentium, PLP complex
分子名称: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, D(-)-TARTARIC ACID
著者Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-12-21
公開日2017-01-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.835 Å)
主引用文献Crystal structure of BioA / 7,8-diaminopelargonic acid aminotransferase / DAPA synthase from Citrobacter rodentium, PLP complex
To Be Published
5TCJ
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BU of 5tcj by Molmil
Crystal structure of tryptophan synthase from M. tuberculosis - aminoacrylate and BRD4592-bound form
分子名称: (2R,3S,4R)-3-(2'-fluoro[1,1'-biphenyl]-4-yl)-4-(hydroxymethyl)azetidine-2-carbonitrile, 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, CESIUM ION, ...
著者Michalska, K, Maltseva, N, Jedrzejczak, R, Wellington, S, Nag, P.P, Fisher, S.L, Schreiber, S.L, Hung, D.T, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-09-15
公開日2017-05-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Nat. Chem. Biol., 13, 2017
6ORT
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BU of 6ort by Molmil
Crystal Structure of Bos taurus Mxra8 Ectodomain
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Matrix remodeling-associated protein 8
著者Fremont, D.H, Kim, A.S, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-04-30
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis.
Cell Host Microbe, 27, 2020
6OYF
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The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo1 serine module
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FORMIC ACID, ...
著者Tan, K, Zhou, M, Jedrzejczak, R, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-05-14
公開日2019-05-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains.
Curr Res Struct Biol, 2, 2020
5T1V
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Crystal structure of Zika virus NS2B-NS3 protease in apo-form.
分子名称: NS2B-NS3 protease,NS2B-NS3 protease
著者Nocadello, S, Light, S.H, Minasov, G, Shuvalova, L, Cardona-Correa, A.A, Ojeda, I, Vargas, J, Johnson, M.E, Lee, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-08-22
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of Zika virus NS2B-NS3 protease in apo-form.
To Be Published
5VQB
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Crystal structure of rifampin monooxygenase from Streptomyces venezuelae, complex with FAD
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Cox, G, Kelso, J, Stogios, P.J, Savchenko, A, Anderson, W.F, Wright, G.D, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-05-08
公開日2017-08-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.391 Å)
主引用文献Rox, a Rifamycin Resistance Enzyme with an Unprecedented Mechanism of Action.
Cell Chem Biol, 25, 2018
5VGM
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Crystal structure of dihydroorotase pyrC from Vibrio cholerae in complex with zinc at 1.95 A resolution.
分子名称: ACETATE ION, CHLORIDE ION, Dihydroorotase, ...
著者Lipowska, J, Shabalin, I.G, Miks, C.D, Winsor, J, Cooper, D.R, Shuvalova, L, Kwon, K, Lewinski, K, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-04-11
公開日2017-04-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Pyrimidine biosynthesis in pathogens - Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae.
Int.J.Biol.Macromol., 136, 2019
5ULB
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Crystal structure of sugar ABC transporter from Yersinia enterocolitica subsp. enterocolitica 8081
分子名称: 5-Se-methyl-5-seleno-alpha-D-ribofuranose, 5-Se-methyl-5-seleno-beta-D-ribofuranose, Putative sugar ABC transporter
著者Nocek, B, Bigelow, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-01-24
公開日2018-09-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Crystal structure of sugar ABC transporter from Yersinia enterocolitica subsp. enterocolitica 8081
To Be Published
5V01
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Crystal structure of the competence damage-inducible protein A (ComA) from Klebsiella pneumoniae subsp. pneumoniae MGH 78578
分子名称: CHLORIDE ION, Competence damage-inducible protein A, SODIUM ION
著者Borek, D, Wawrzak, Z, Grimshaw, S, Sandoval, J, Evdokimova, E, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-28
公開日2017-03-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of the competence damage-inducible protein A (ComA) from Klebsiella pneumoniae subsp. pneumoniae MGH 78578
To Be Published

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件を2024-07-17に公開中

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