6ORT

Crystal Structure of Bos taurus Mxra8 Ectodomain

Summary for 6ORT

Entry DOI	10.2210/pdb6ort/pdb
Descriptor	Matrix remodeling-associated protein 8, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	receptor, chikungunya virus, cow, bovine, alphavirus, moo insertion, structural genomics, center for structural genomics of infectious diseases, csgid, membrane protein
Biological source	Bos taurus (Bovine)
Total number of polymer chains	1
Total formula weight	32711.65
Authors	Fremont, D.H.,Kim, A.S.,Nelson, C.A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2019-04-30, release date: 2020-03-04, Last modification date: 2023-10-11)
Primary citation	Kim, A.S.,Zimmerman, O.,Fox, J.M.,Nelson, C.A.,Basore, K.,Zhang, R.,Durnell, L.,Desai, C.,Bullock, C.,Deem, S.L.,Oppenheimer, J.,Shapiro, B.,Wang, T.,Cherry, S.,Coyne, C.B.,Handley, S.A.,Landis, M.J.,Fremont, D.H.,Diamond, M.S. An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis. Cell Host Microbe, 27:428-440.e9, 2020 Cited by PubMed: 32075743 DOI: 10.1016/j.chom.2020.01.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation