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3CC0
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BU of 3cc0 by Molmil
The Dvl2 PDZ Domain in Complex with the N3 Inhibitory Peptide
分子名称: Dishevelled-2
著者Appleton, B.A, Wiesmann, C.
登録日2008-02-23
公開日2009-03-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Inhibition of Wnt signaling by Dishevelled PDZ peptides
Nat.Chem.Biol., 5, 2009
6LL9
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BU of 6ll9 by Molmil
Crystal structure of D-alanine-D-alanine ligase from Aeromonas hydrophila
分子名称: D-ALANINE, D-alanine--D-alanine ligase
著者Zhang, H.
登録日2019-12-22
公開日2020-07-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Insights into the Inhibition ofAeromonas hydrophilad-Alanine-d-Alanine Ligase by Integration of Kinetics and Structural Analysis.
J.Agric.Food Chem., 68, 2020
2ZEU
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BU of 2zeu by Molmil
S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with BPH-715
分子名称: 3-(DECYLOXY)-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM, Geranylgeranyl pyrophosphate synthetase
著者Guo, R.T, Chen, C.K.-M, Cao, R, Oldfield, E, Wang, A.H.-J.
登録日2007-12-17
公開日2008-12-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation
J.Am.Chem.Soc., 131, 2009
2ZEV
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BU of 2zev by Molmil
S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Magnesium, IPP and BPH-715
分子名称: 3-(DECYLOXY)-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, ...
著者Guo, R.T, Chen, C.K.-M, Cao, R, Oldfield, E, Wang, A.H.-J.
登録日2007-12-17
公開日2008-12-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation
J.Am.Chem.Soc., 131, 2009
5VL7
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BU of 5vl7 by Molmil
PCSK9 complex with Fab33
分子名称: Fab33 heavy chain, Fab33 light chain, Proprotein convertase subtilisin/kexin type 9
著者Eigenbrot, C, Shia, S.
登録日2017-04-25
公開日2017-08-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists.
Nat. Struct. Mol. Biol., 24, 2017
5VLK
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BU of 5vlk by Molmil
Short PCSK9 delta-P' complex with shrunken peptide bearing homo-Arginine
分子名称: ACE-THR-VAL-PHE-THR-SER-TRP-GLU-GLU-TYR-LEU-ASP-TRP-VAL-NH2 peptide, ACE-TRP-ASN-LEU-VAL-HRG-ILE-GLY-LEU-LEU peptide, CALCIUM ION, ...
著者Eigenbrot, C, Ultsch, M.
登録日2017-04-25
公開日2017-08-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists.
Nat. Struct. Mol. Biol., 24, 2017
5VLP
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BU of 5vlp by Molmil
PCSK9 complex with LDLR antagonist peptide and Fab7G7
分子名称: Fab7G7 heavy chain, Fab7G7 light chain, LDLR antagonist peptide, ...
著者Eigenbrot, C, Ultsch, M.
登録日2017-04-25
公開日2017-08-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists.
Nat. Struct. Mol. Biol., 24, 2017
5VLA
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BU of 5vla by Molmil
Short PCSK9 delta-P' complex with Fusion2 peptide
分子名称: CALCIUM ION, Proprotein convertase subtilisin/kexin type 9, THR-VAL-PHE-THR-SER-TRP-GLU-GLU-TYR-LEU-ASP-TRP-VAL-MET-PRO-TRP-ASN-LEU-VAL-ARG-ILE-GLY-LEU-LEU
著者Eigenbrot, C, Ultsch, M.
登録日2017-04-25
公開日2017-08-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists.
Nat. Struct. Mol. Biol., 24, 2017
7VWP
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BU of 7vwp by Molmil
Structure of the flavin-dependent monooxygenase FlsO1 from the biosynthesis of fluostatinsin
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, FlsO1, PHOSPHATE ION, ...
著者Zhang, Y, Yang, C, Zhang, L, Zhang, C.
登録日2021-11-11
公開日2022-09-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Biochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation
Nat Commun, 13, 2022
5VLH
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BU of 5vlh by Molmil
Short PCSK9 delta-P' complex with peptide Pep1
分子名称: ACE-THR-VAL-PHE-THR-SER-TRP-GLU-GLU-TYR-LEU-ASP-TRP-VAL-NH2, CALCIUM ION, CYS-ARG-LEU-PRO-TRP-ASN-LEU-GLN-ARG-ILE-GLY-LEU-PRO-CYS, ...
著者Eigenbrot, C, Ultsch, M.
登録日2017-04-25
公開日2017-08-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists.
Nat. Struct. Mol. Biol., 24, 2017
5VLL
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BU of 5vll by Molmil
Short PCSK9 delta-P' complex with peptide Pep3
分子名称: ACE-THR-VAL-PHE-THR-SER-TRP-GLU-GLU-TYR-LEU-ASP-TRP-VAL-NH2, CALCIUM ION, CYS-PHE-ILE-PRO-TRP-ASN-LEU-GLN-ARG-ILE-GLY-LEU-LEU-CYS, ...
著者Eigenbrot, C, Ultsch, M.
登録日2017-04-25
公開日2017-08-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists.
Nat. Struct. Mol. Biol., 24, 2017
6A9Y
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BU of 6a9y by Molmil
The crystal structure of Mu homology domain of SGIP1
分子名称: SH3-containing GRB2-like protein 3-interacting protein 1
著者Feng, Y, Liu, X.
登録日2018-07-16
公開日2018-09-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献SGIP1 dimerizes via intermolecular disulfide bond in mu HD domain during cellular endocytosis.
Biochem. Biophys. Res. Commun., 505, 2018
6J2R
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BU of 6j2r by Molmil
Crystal structure of Striga hermonthica HTL8 (ShHTL8)
分子名称: GLYCEROL, Hyposensitive to light 8
著者Zhang, Y.Y, Xi, Z.
登録日2019-01-02
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure and biochemical characterization of Striga hermonthica HYPO-SENSITIVE TO LIGHT 8 (ShHTL8) in strigolactone signaling pathway.
Biochem.Biophys.Res.Commun., 523, 2020
6VPT
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BU of 6vpt by Molmil
Crystal structure and mechanistic molecular modeling studies of Rv3377c: the Mycobacterium tuberculosis diterpene cyclase
分子名称: Cyclase
著者Zhang, T, Prach, L, DiMaio, F, Siegel, J.
登録日2020-02-04
公開日2020-12-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.718 Å)
主引用文献Crystal Structure and Mechanistic Molecular Modeling Studies of Mycobacterium tuberculosis Diterpene Cyclase Rv3377c.
Biochemistry, 59, 2020
6GFM
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BU of 6gfm by Molmil
Crystal structure of the Escherichia coli nucleosidase PpnN (pppGpp-form)
分子名称: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate)
著者Zhang, Y, Baerentsen, R.L, Gerdes, K, Brodersen, D.E.
登録日2018-05-01
公開日2019-04-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch.
Mol.Cell, 74, 2019
6GFL
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BU of 6gfl by Molmil
Crystal structure of the Escherichia coli nucleosidase PpnN (apo form)
分子名称: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase
著者Zhang, Y, Baerentsen, R.L, Gerdes, K, Brodersen, D.E.
登録日2018-05-01
公開日2019-04-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch.
Mol.Cell, 74, 2019
4HK2
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BU of 4hk2 by Molmil
U7Ub25.2540
分子名称: SULFATE ION, Ubiquitin
著者Murray, J.M, Rouge, L.
登録日2012-10-14
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Potent and selective inhibitors of USP7/HAUSP activity by protein conformational stabilization
to be published
4HJK
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BU of 4hjk by Molmil
U7Ub7 Disulfide variant
分子名称: PHOSPHATE ION, Ubiquitin
著者Murray, J.M, Rouge, L.
登録日2012-10-12
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.784 Å)
主引用文献Potent and selective inhibitors of USP7/HAUSP activity by protein conformational stabilization
to be published
4NMX
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BU of 4nmx by Molmil
PCSK9(deltaCRD) in complex with phage-derived inhibitory peptide 2-8
分子名称: Proprotein convertase subtilisin/kexin type 9, peptide 2-8
著者Eigenbrot, C, Shia, S.
登録日2013-11-15
公開日2013-12-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Identification of a Small Peptide That Inhibits PCSK9 Protein Binding to the Low Density Lipoprotein Receptor.
J.Biol.Chem., 289, 2014
8JD9
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BU of 8jd9 by Molmil
Cyro-EM structure of the Na+/H+ antipoter SOS1 from Arabidopsis thaliana,class1
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Sodium/hydrogen exchanger 7
著者Yang, G.H, Zhang, Y.M, Zhou, J.Q, Jia, Y.T, Xu, X, Fu, P, Wu, H.Y.
登録日2023-05-13
公開日2023-11-08
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Structural basis for the activity regulation of Salt Overly Sensitive 1 in Arabidopsis salt tolerance.
Nat.Plants, 9, 2023
8JDA
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BU of 8jda by Molmil
Cyro-EM structure of the Na+/H+ antipoter SOS1 from Arabidopsis thaliana,class2
分子名称: Sodium/hydrogen exchanger 7
著者Yang, G.H, Zhang, Y.M, Zhou, J.Q, Jia, Y.T, Xu, X, Fu, P, Wu, H.Y.
登録日2023-05-13
公開日2023-11-08
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Structural basis for the activity regulation of Salt Overly Sensitive 1 in Arabidopsis salt tolerance.
Nat.Plants, 9, 2023
8H97
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BU of 8h97 by Molmil
GH86 agarase Aga86A_Wa
分子名称: Beta-agarase, CALCIUM ION, HEXAETHYLENE GLYCOL
著者Zhang, Y.Y, Dong, S, Feng, Y.G, Chang, Y.G.
登録日2022-10-25
公開日2023-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.194 Å)
主引用文献Structural characterization on a beta-agarase Aga86A_Wa from Wenyingzhuangia aestuarii reveals the prevalent methyl-galactose accommodation capacity of GH86 enzymes at subsite -1.
Carbohydr Polym, 306, 2023
5TIG
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BU of 5tig by Molmil
CRYSTAL STRUCTURE OF 4-OXALOCROTONATE TAUTOMERASE INACTIVATED BY BrHPD
分子名称: (3E)-5-hydroxy-2-oxopent-3-enoic acid, 2-hydroxymuconate tautomerase
著者Zhang, Y, Li, W, Stack, T.
登録日2016-10-02
公開日2018-02-21
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates.
Biochemistry, 57, 2018
6BGN
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BU of 6bgn by Molmil
Crystal Structure of 4-Oxalocrotonate Tautomerase After Incubation with 5-Fluoro-2-hydroxy-2,4-pentadienoate
分子名称: 2-hydroxymuconate tautomerase, 5-fluoranyl-2-oxidanylidene-pentanoic acid, GLYCEROL, ...
著者Zhang, Y, Li, W, Stack, T.
登録日2017-10-29
公開日2018-02-21
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates.
Biochemistry, 57, 2018
6JJI
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BU of 6jji by Molmil
Crystal structure of a two-quartet RNA parallel G-quadruplex complexed with the porphyrin TMPyP4 (1:1)
分子名称: (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, POTASSIUM ION, RNA (5'-R(*GP*GP*CP*UP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3')
著者Zhang, Y.S, Parkinson, G.N, Wei, D.G.
登録日2019-02-25
公開日2020-02-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Res., 48, 2020

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