5VLL
Short PCSK9 delta-P' complex with peptide Pep3
Summary for 5VLL
Entry DOI | 10.2210/pdb5vll/pdb |
Related | 5VL7 5VLA 5VLH 5VLK 5VLP |
Descriptor | Proprotein convertase subtilisin/kexin type 9, CYS-PHE-ILE-PRO-TRP-ASN-LEU-GLN-ARG-ILE-GLY-LEU-LEU-CYS, ACE-THR-VAL-PHE-THR-SER-TRP-GLU-GLU-TYR-LEU-ASP-TRP-VAL-NH2, ... (5 entities in total) |
Functional Keywords | proprotein convertase, subtilisin, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 53200.12 |
Authors | Eigenbrot, C.,Ultsch, M. (deposition date: 2017-04-25, release date: 2017-08-16, Last modification date: 2023-10-04) |
Primary citation | Zhang, Y.,Ultsch, M.,Skelton, N.J.,Burdick, D.J.,Beresini, M.H.,Li, W.,Kong-Beltran, M.,Peterson, A.,Quinn, J.,Chiu, C.,Wu, Y.,Shia, S.,Moran, P.,Di Lello, P.,Eigenbrot, C.,Kirchhofer, D. Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists. Nat. Struct. Mol. Biol., 24:848-856, 2017 Cited by PubMed: 28825733DOI: 10.1038/nsmb.3453 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.37 Å) |
Structure validation
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