5VLL
Short PCSK9 delta-P' complex with peptide Pep3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proprotein convertase subtilisin/kexin type 9 | polymer | 460 | 49784.1 | 1 | UniProt (Q8NBP7) Pfam (PF05922) Pfam (PF00082) | Homo sapiens (Human) | Neural apoptosis-regulated convertase 1,NARC-1,Proprotein convertase 9,PC9,Subtilisin/kexin-like protease PC9 |
| 2 | B (Y) | CYS-PHE-ILE-PRO-TRP-ASN-LEU-GLN-ARG-ILE-GLY-LEU-LEU-CYS | polymer | 14 | 1677.1 | 1 | synthetic construct | ||
| 3 | C (Z) | ACE-THR-VAL-PHE-THR-SER-TRP-GLU-GLU-TYR-LEU-ASP-TRP-VAL-NH2 | polymer | 15 | 1698.8 | 1 | synthetic construct | ||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E, F, G (A, Y, Z) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A: 1 - 452 (UniProt: Q8NBP7)
| PDB | External Database | Details |
|---|---|---|
| Ser 167 | Arg 167 | engineered mutation |
| Asn 453 | - | expression tag |
| Ser 454 | - | expression tag |
| His 455 | - | expression tag |
| His 456 | - | expression tag |
| His 457 | - | expression tag |
| His 458 | - | expression tag |
| His 459 | - | expression tag |
| His 460 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 53160.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 53200.1 |
