4HK2

U7Ub25.2540

Summary for 4HK2

• Entry DOI: 10.2210/pdb4hk2/pdb
• Related: 4HJK
• Descriptor: Ubiquitin, SULFATE ION (3 entities in total)
• Functional Keywords: computationally designed ubiquitin, usp7, signaling protein-inhibitor complex, signaling protein/inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Ubiquitin: Cytoplasm (By similarity): P0CG48
• Total number of polymer chains: 4
• Total formula weight: 35736.80

Authors

Murray, J.M.,Rouge, L. (deposition date: 2012-10-14, release date: 2012-11-21, Last modification date: 2023-09-20)

• Primary citation: Zhang, Y.,Zhou, L.,Rouge, L.,Phillips, A.H.,Lam, C.,Liu, P.,Sandoval, W.,Helgason, E.,Murray, J.M.,Wertz, I.,Corn, J.E.; Potent and selective inhibitors of USP7/HAUSP activity by protein conformational stabilization; to be published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)