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8SAK
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BU of 8sak by Molmil
BtCoV-422 in complex with neutralizing antibody JC57-11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者McFadden, E, McLellan, J.S.
登録日2023-04-01
公開日2023-10-04
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.
Sci Transl Med, 15, 2023
8T7A
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BU of 8t7a by Molmil
Cryo-EM structure of RSV preF in complex with Fab 2.4K
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2.4K Fab Heavy Chain, 2.4K Fab Light Chain, ...
著者McCool, R.S, McLellan, J.S.
登録日2023-06-20
公開日2023-09-13
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein elicits antibodies targeting a membrane-proximal epitope.
J.Virol., 97, 2023
8U1R
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BU of 8u1r by Molmil
Prefusion-stabilized Langya virus F protein, variant G99C/I109C
分子名称: Fusion glycoprotein F
著者Byrne, P.O, McLellan, J.S.
登録日2023-09-01
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Prefusion-stabilized Langya virus F protein, variant G99C/I109C
To Be Published
8TMA
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BU of 8tma by Molmil
Antibody N3-1 bound to RBD in the up conformation
分子名称: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
著者Hsieh, C.-L, McLellan, J.S.
登録日2023-07-29
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
8TM1
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BU of 8tm1 by Molmil
Antibody N3-1 bound to RBDs in the up and down conformations
分子名称: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
著者Hsieh, C.-L, McLellan, J.S.
登録日2023-07-27
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
8U1G
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BU of 8u1g by Molmil
Prefusion-stabilized SARS-CoV-2 S2 subunit
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
著者Hsieh, C.-L, McLellan, J.S.
登録日2023-08-31
公開日2024-01-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of prefusion-stabilized SARS-CoV-2 S2-only antigen
To Be Published
8TW3
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BU of 8tw3 by Molmil
hMPV fusion protein complexed with single domain antibodies sdHMPV16 and sdHMPV12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein, Single domain antibody sdHMPV12, ...
著者Rush, S.A, McLellan, J.S.
登録日2023-08-19
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein.
Mbio, 15, 2024
8V62
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BU of 8v62 by Molmil
Structure of the Human Respirovirus 3 Fusion Protein Bound to Camelid Nanobodies 1D10 and 4C06
分子名称: Camelid nanobody 1D10, Camelid nanobody 4C06, Fusion glycoprotein F0
著者Johnson, N.J, Ramamohan, A.R, McLellan, J.S.
登録日2023-12-01
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for potent neutralization of human respirovirus type 3 by single-domain camelid antibodies
To Be Published
7LVW
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BU of 7lvw by Molmil
Structure of RSV F in Complex with VHH Cl184
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, F-VHH-Cl184, ...
著者Hsieh, C.-L, McLellan, J.S.
登録日2021-02-26
公開日2021-03-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody.
J.Virol., 95, 2021
7LVU
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BU of 7lvu by Molmil
Structure of RSV F-directed VHH Cl184
分子名称: F-VHH-Cl184
著者Hsieh, C.-L, McLellan, J.S.
登録日2021-02-26
公開日2021-03-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody.
J.Virol., 95, 2021
7LUC
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BU of 7luc by Molmil
Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B
分子名称: 01.4B Fab Heavy chain, 01.4B Fab Light chain, 32.4K Fab Heavy chain, ...
著者Wrapp, D, McLellan, J.S.
登録日2021-02-22
公開日2021-04-21
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
7M1C
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BU of 7m1c by Molmil
Crystal structure of the HCMV pentamer-specific antibody 1-32
分子名称: 1-32 Fab Heavy Chain, 1-32 Fab Light Chain
著者Wrapp, D, McLellan, J.S.
登録日2021-03-12
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7LYV
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BU of 7lyv by Molmil
Crystal structure of the HCMV pentamer-specific antibody 1-103
分子名称: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain
著者Wrapp, D, Jones, H.G, McLellan, J.S.
登録日2021-03-08
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7M22
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BU of 7m22 by Molmil
Cryo-EM structure of the HCMV pentamer bound by human neuropilin 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein UL130, ...
著者Wrapp, D, McLellan, J.S.
登録日2021-03-15
公開日2021-08-11
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7LYW
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BU of 7lyw by Molmil
Crystal structure of the HCMV pentamer-specific antibody 2-25
分子名称: 2-25 Fab Heavy Chain, 2-25 Fab Light Chain
著者Wrapp, D, Mishra, A.K, McLellan, J.S.
登録日2021-03-08
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7M30
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BU of 7m30 by Molmil
Cryo-EM structure of the HCMV pentamer bound by antibodies 1-103, 1-32 and 2-25
分子名称: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain, 1-32 Fab Heavy Chain, ...
著者Wrapp, D, McLellan, J.S.
登録日2021-03-17
公開日2021-08-11
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7M8J
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BU of 7m8j by Molmil
SARS-CoV-2 S-NTD + Fab CM25
分子名称: CM25 Fab - Heavy Chain, CM25 Fab - Light Chain, Spike protein S1
著者Johnson, N.V, Mclellan, J.S.
登録日2021-03-29
公開日2021-05-19
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes.
Science, 372, 2021
7KBB
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BU of 7kbb by Molmil
Cryo-EM structure of the HCMV pentamer bound by Fabs 2-18 and 8I21
分子名称: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain, 8I21 Fab Heavy Chain, ...
著者Wrapp, D, McLellan, J.S.
登録日2020-10-01
公開日2021-08-11
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7KBA
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BU of 7kba by Molmil
Crystal structure of the HCMV pentamer-specific Fab 2-18
分子名称: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain
著者Wrapp, D, McLellan, J.S.
登録日2020-10-01
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7L3N
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BU of 7l3n by Molmil
SARS-CoV 2 Spike Protein bound to LY-CoV555
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LY-CoV555 Fab heavy chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2020-12-18
公開日2021-02-03
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection.
Biorxiv, 2020
7LUE
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BU of 7lue by Molmil
Prefusion RSV F glycoprotein bound by neutralizing site V-directed antibody ADI-14442
分子名称: Fusion glycoprotein F0, Heavy chain of human antibody Fab ADI-14442, Light chain of human antibody Fab ADI-14442
著者Gilman, M.S.A, McLellan, J.S.
登録日2021-02-22
公開日2021-06-16
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
7LUD
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BU of 7lud by Molmil
Crystal structure of Fab ADI-14442
分子名称: ADI-14442 Fab Heavy chain, ADI-14442 Fab Light chain, SULFATE ION
著者Rush, S.A, McLellan, J.S.
登録日2021-02-22
公開日2021-06-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
7KX4
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BU of 7kx4 by Molmil
Anti-CCHFV ADI-36121 Fab
分子名称: ADI-36121 Fab heavy chain, ADI-36121 Fab light chain
著者Mishra, A.K, McLellan, J.S.
登録日2020-12-03
公開日2021-12-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.
Science, 375, 2022
7L7R
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BU of 7l7r by Molmil
CCHFV Gc prefusion monomer bound to ADI-36121 and ADI-37801 Fabs
分子名称: ADI-36121 Fab heavy chain, ADI-36121 Fab light chain, ADI-37801 Fab heavy chain, ...
著者Mishra, A.K, McLellan, J.S.
登録日2020-12-30
公開日2021-12-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.
Science, 375, 2022
6UOE
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BU of 6uoe by Molmil
3-25 Fab germline-reversion variant bound to an HCMV gB-derived peptide
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-25 Fab heavy chain, 3-25 Fab light chain, ...
著者Wrapp, D, McLellan, J.S.
登録日2019-10-14
公開日2020-07-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step.
Plos Pathog., 16, 2020

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件を2024-06-12に公開中

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