8DCM

Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab

This is a non-PDB format compatible entry.

Summary for 8DCM

• Entry DOI: 10.2210/pdb8dcm/pdb
• Descriptor: BINTOXB/22 Fab heavy chain, BINTOXB/22 Fab light chain, ADP-ribosylating binary toxin binding subunit CdtB, ... (6 entities in total)
• Functional Keywords: virulence, antibodies, neutralization, bacteria, toxin, toxin-immune system complex, toxin/immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 3
• Total formula weight: 128489.27

Authors

Goldsmith, J.A.,McLellan, J.S. (deposition date: 2022-06-16, release date: 2023-04-05, Last modification date: 2023-10-25)

• Primary citation: Goldsmith, J.A.,Dewar, V.,Hermand, P.,Blais, N.,McLellan, J.S.; Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.; J.Bacteriol., 205:e0045622-e0045622, 2023; PubMed: 36951574; DOI: 10.1128/jb.00456-22

Experimental method

X-RAY DIFFRACTION (2.5 Å)