8DCM

Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	BINTOXB/22 Fab heavy chain	polymer	229	24863.0	1		Mus musculus
2	B	BINTOXB/22 Fab light chain	polymer	212	23441.7	1		Mus musculus
3	C	ADP-ribosylating binary toxin binding subunit CdtB	polymer	711	80041.3	1	UniProt (A8DS70) Pfam (PF07691) Pfam (PF03495) Pfam (PF17475) Pfam (PF17476) In PDB	Clostridioides difficile	ADP-ribosyltransferase binding component,CdtB, proCDTb
4	C	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
5	C	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
6		water	water		18.0	259	Chemie (HOH)

Sequence modifications

C: 43 - 746 (UniProt: A8DS70)

PDB	External Database	Details
Met 42	-	initiating methionine
His 747	-	expression tag
His 748	-	expression tag
His 749	-	expression tag
His 750	-	expression tag
His 751	-	expression tag
His 752	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	128346.0
Non-Polymers*	Number of molecules	4
	Total formula weight	143.2
All*	Total formula weight	128489.3

*Water molecules are not included.