3ENH
 
 | | Crystal structure of Cgi121/Bud32/Kae1 complex | | 分子名称: | HEXATANTALUM DODECABROMIDE, Putative O-sialoglycoprotein endopeptidase, Uncharacterized protein MJ0187 | | 著者 | Neculai, D. | | 登録日 | 2008-09-25 | | 公開日 | 2008-10-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Atomic Structure of the KEOPS Complex: An Ancient Protein Kinase-Containing Molecular Machine
Mol.Cell, 32, 2008
|
|
8T7F
 | | Structure of the S1 variant of Fab F1 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, S1 variant of Fab F1 heavy chain, S1 variant of Fab F1 light chain, ... | | 著者 | Singer, A.U, Bruce, H.A, Enderle, L, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. | | 登録日 | 2023-06-20 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
|
|
8T58
 | |
8TS5
 | | Structure of the apo FabS1C_C1 | | 分子名称: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | | 著者 | Singer, A.U, Bruce, H.A, Blazer, L.L, Adams, J.J, Sicheri, F, Sidhu, S.S. | | 登録日 | 2023-08-10 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
|
|
8TRT
 | | Structure of the EphA2 CRD bound to FabS1CE_C1, monoclinic form | | 分子名称: | CHLORIDE ION, Ephrin type-A receptor 2, S1CE variant of Fab C1 heavy chain, ... | | 著者 | Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. | | 登録日 | 2023-08-10 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
|
|
8TRS
 | | Structure of the EphA2 CRD bound to FabS1CE_C1, trigonal form | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. | | 登録日 | 2023-08-10 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
|
|
3ENC
 | |
3ENP
 | | Crystal structure of human cgi121 | | 分子名称: | TP53RK-binding protein | | 著者 | Haffani, Y.Z, Ceccarelli, D.F, Neculai, D, Mao, D.Y, Sicheri, F. | | 登録日 | 2008-09-25 | | 公開日 | 2008-11-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Mol.Cell, 32, 2008
|
|
3EN9
 | |
3ENO
 | |
7MM1
 | | PTP1B in complex with TCS401 by Native S-SAD at Room Temperature | | 分子名称: | 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Greisman, J.B, Dalton, K.M, Hekstra, D.R. | | 登録日 | 2021-04-29 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Native SAD phasing at room temperature.
Acta Crystallogr D Struct Biol, 78, 2022
|
|
7LUO
 | | N-terminus of Skp2 bound to Cyclin A | | 分子名称: | S-phase kinase-associated protein 2,Cyclin-A2, Skp2 Motif 1 uncharacterized fragment 1, Skp2 Motif 1 uncharacterized fragment 2 | | 著者 | Kelso, S, Ceccarelli, D.F, Sicheri, F. | | 登録日 | 2021-02-22 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Bipartite binding of the N terminus of Skp2 to cyclin A.
Structure, 29, 2021
|
|
7L84
 | |
6B0T
 | |
6C16
 | |
7UKZ
 | |
6BVA
 | |
7U3G
 | | GID4 in complex with compound 67 | | 分子名称: | (1R)-1-phenyl-1,2,3,4-tetrahydroisoquinolin-5-amine, Glucose-induced degradation protein 4 homolog | | 著者 | Chana, C.K, Sicheri, F. | | 登録日 | 2022-02-27 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.244 Å) | | 主引用文献 | Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
J.Med.Chem., 65, 2022
|
|
7U3K
 | | GID4 in complex with compound 89 | | 分子名称: | GLYCEROL, Glucose-induced degradation protein 4 homolog, N-butylglycyl-4-tert-butyl-D-phenylalanyl-3-methoxy-N-methyl-L-phenylalaninamide | | 著者 | Chana, C.K, Sicheri, F. | | 登録日 | 2022-02-27 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
J.Med.Chem., 65, 2022
|
|
7U3I
 | | GID4 in complex with compound 16 | | 分子名称: | 3-{[(5S)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]amino}phenol, GLYCEROL, Glucose-induced degradation protein 4 homolog | | 著者 | Chana, C.K, Sicheri, F. | | 登録日 | 2022-02-27 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.991 Å) | | 主引用文献 | Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
J.Med.Chem., 65, 2022
|
|
7U3J
 | | GID4 in complex with compound 88 | | 分子名称: | (2S)-2-{[(2S)-2-({N-[(2,4-dimethoxyphenyl)methyl]glycyl}amino)-2-(thiophen-2-yl)acetyl]amino}-N-methyl-4-phenylbutanamide, GLYCEROL, Glucose-induced degradation protein 4 homolog | | 著者 | Chana, C.K, Sicheri, F. | | 登録日 | 2022-02-27 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.642 Å) | | 主引用文献 | Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
J.Med.Chem., 65, 2022
|
|
7U3E
 | | GID4 in complex with compound 1 | | 分子名称: | Glucose-induced degradation protein 4 homolog, tert-butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate | | 著者 | Chana, C.K, Sicheri, F. | | 登録日 | 2022-02-27 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.852 Å) | | 主引用文献 | Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
J.Med.Chem., 65, 2022
|
|
7U3F
 | | GID4 in complex with compound 4 | | 分子名称: | (4R)-4-(4-methoxyphenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine, GLYCEROL, Glucose-induced degradation protein 4 homolog | | 著者 | Chana, C.K, Sicheri, F. | | 登録日 | 2022-02-27 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
J.Med.Chem., 65, 2022
|
|
7U3H
 | | GID4 in complex with compound 7 | | 分子名称: | (5R)-N-(4-fluorophenyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-amine, Glucose-induced degradation protein 4 homolog | | 著者 | Chana, C.K, Sicheri, F. | | 登録日 | 2022-02-27 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | | 主引用文献 | Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
J.Med.Chem., 65, 2022
|
|
7U3L
 | | GID4 in complex with compound 91 | | 分子名称: | GLYCEROL, Glucose-induced degradation protein 4 homolog, Nalpha-{(2R,4E)-2-[(N-benzylglycyl)amino]-5-phenylpent-4-enoyl}-N,4-dimethyl-L-phenylalaninamide | | 著者 | Chana, C.K, Sicheri, F. | | 登録日 | 2022-02-27 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | | 主引用文献 | Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
J.Med.Chem., 65, 2022
|
|
