7UKZ
CDK11 in complex with small molecule inhibitor OTS964
Summary for 7UKZ
| Entry DOI | 10.2210/pdb7ukz/pdb |
| Descriptor | Cyclin-dependent kinase 11B, OTS964, SULFATE ION (3 entities in total) |
| Functional Keywords | kinase, inhibitor, transferase, transferase-inhibitor complex, transferase/inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 6 |
| Total formula weight | 222474.34 |
| Authors | Kelso, S.,Sicheri, F. (deposition date: 2022-04-03, release date: 2022-10-26, Last modification date: 2023-10-25) |
| Primary citation | Kelso, S.,O'Brien, S.,Kurinov, I.,Angers, S.,Sicheri, F. Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964. Structure, 30:1615-, 2022 Cited by PubMed: 36327972DOI: 10.1016/j.str.2022.10.003 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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