7UKZ
CDK11 in complex with small molecule inhibitor OTS964
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Cyclin-dependent kinase 11B | polymer | 319 | 36590.5 | 6 | UniProt (P21127) Pfam (PF00069) In PDB | Homo sapiens (human) | Cell division cycle 2-like protein kinase 1,CLK-1,Cell division protein kinase 11B,Galactosyltransferase-associated protein kinase p58/GTA,PITSLRE serine/threonine-protein kinase CDC2L1,p58 CLK-1 |
2 | A, B, C, D, E... | OTS964 | non-polymer | 392.5 | 6 | Chemie (NK3) | |||
3 | A, B, C, D, E... | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) |
Sequence modifications
A, B, C, D, E, F: 72 - 380 (UniProt: P21127)
PDB | External Database | Details |
---|---|---|
Gly 68 | - | expression tag |
Ala 69 | - | expression tag |
Met 70 | - | expression tag |
Gly 71 | - | expression tag |
Lys 381 | - | expression tag |
Leu 382 | - | expression tag |
Val 383 | - | expression tag |
Glu 384 | - | expression tag |
Lys 385 | - | expression tag |
Tyr 386 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 219542.9 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 2931.5 | |
All* | Total formula weight | 222474.3 |