7UKZ
CDK11 in complex with small molecule inhibitor OTS964
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Cyclin-dependent kinase 11B | polymer | 319 | 36590.5 | 6 | UniProt (P21127) Pfam (PF00069) | Homo sapiens (human) | Cell division cycle 2-like protein kinase 1,CLK-1,Cell division protein kinase 11B,Galactosyltransferase-associated protein kinase p58/GTA,PITSLRE serine/threonine-protein kinase CDC2L1,p58 CLK-1 |
| 2 | G, I, K, M, O... (A, B, C, D, E...) | OTS964 | non-polymer | 392.5 | 6 | Chemie (NK3) | |||
| 3 | H, J, L, N, P... (A, B, C, D, E...) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) |
Sequence modifications
A, B, C, D, E, F: 72 - 380 (UniProt: P21127)
| PDB | External Database | Details |
|---|---|---|
| Gly 68 | - | expression tag |
| Ala 69 | - | expression tag |
| Met 70 | - | expression tag |
| Gly 71 | - | expression tag |
| Lys 381 | - | expression tag |
| Leu 382 | - | expression tag |
| Val 383 | - | expression tag |
| Glu 384 | - | expression tag |
| Lys 385 | - | expression tag |
| Tyr 386 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 219542.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2931.5 | |
| All* | Total formula weight | 222474.3 |
