8SLT
 
 | | Crystal structure of human STEP (PTPN5) at physiological temperature (310 K) and ambient pressure (0.1 MPa) | | 分子名称: | SULFATE ION, Tyrosine-protein phosphatase non-receptor type 5 | | 著者 | Ebrahim, A, Guerrero, L, Riley, B.T, Kim, M, Huang, Q, Finke, A.D, Keedy, D.A. | | 登録日 | 2023-04-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase.
Biorxiv, 2023
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8SLU
 | | Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and high pressure (205 MPa) | | 分子名称: | GLYCEROL, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 5 | | 著者 | Ebrahim, A, Guerrero, L, Riley, B.T, Kim, M, Huang, Q, Finke, A.D, Keedy, D.A. | | 登録日 | 2023-04-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase.
Biorxiv, 2023
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8SLS
 | | Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and ambient pressure (0.1 MPa) | | 分子名称: | GLYCEROL, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 5 | | 著者 | Ebrahim, A, Guerrero, L, Riley, B.T, Kim, M, Huang, Q, Finke, A.D, Keedy, D.A. | | 登録日 | 2023-04-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase.
Biorxiv, 2023
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1XWN
 | | solution structure of cyclophilin like 1(PPIL1) and insights into its interaction with SKIP | | 分子名称: | Peptidyl-prolyl cis-trans isomerase like 1 | | 著者 | Xu, C, Xu, Y, Tang, Y, Wu, J, Shi, Y, Huang, Q, Zhang, Q. | | 登録日 | 2004-11-01 | | 公開日 | 2005-10-18 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of human peptidyl prolyl isomerase like protein 1 and insights into its interaction with SKIP
J.Biol.Chem., 281, 2006
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1JW6
 | | Crystal Structure of the Complex of Concanavalin A and Hexapeptide | | 分子名称: | CALCIUM ION, Concanavalin A, ISOPROPYL ALCOHOL, ... | | 著者 | Zhang, Z, Qian, M, Huang, Q, Jia, Y, Tang, Y. | | 登録日 | 2001-09-02 | | 公開日 | 2001-09-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Crystal structure of the complex of concanavalin A and hexapeptide.
J.Protein Chem., 20, 2001
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6E31
 | | Crystal structure of RIAM in an autoinhibited configuration. | | 分子名称: | Rap1-interacting adapter molecule | | 著者 | Chang, Y.C, Su, W, Zhang, H, Huang, Q, Philips, M.R, Wu, J. | | 登録日 | 2018-07-12 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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1JIR
 | | Crystal Structure of Trypsin Complex with Amylamine in Cyclohexane | | 分子名称: | AMYLAMINE, CALCIUM ION, SULFATE ION, ... | | 著者 | Wu, G, Zhu, G, Huang, Q, Qian, M, Tang, Y. | | 登録日 | 2001-07-02 | | 公開日 | 2001-07-18 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of beta-Trypsin Complex with Amylamine in Cyclohexane
To be Published
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1KVV
 | | Solution Structure Of Protein SRP19 Of The Archaeoglobus fulgidus Signal Recognition Particle, Minimized Average Structure | | 分子名称: | SRP19 | | 著者 | Pakhomova, O.N, Deep, S, Huang, Q, Zwieb, C, Hinck, A.P. | | 登録日 | 2002-01-27 | | 公開日 | 2002-03-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of protein SRP19 of Archaeoglobus fulgidus signal recognition particle.
J.Mol.Biol., 317, 2002
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1OMY
 | | Crystal Structure of a Recombinant alpha-insect Toxin BmKaIT1 from the scorpion Buthus martensii Karsch | | 分子名称: | ACETIC ACID, Alpha-neurotoxin TX12, CHLORIDE ION | | 著者 | Huang, Y, Huang, Q, Chen, H, Tang, Y, Miyake, H, Kusunoki, M. | | 登録日 | 2003-02-26 | | 公開日 | 2003-09-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystallization and preliminary crystallographic study of rBmKalphaIT1, a recombinant alpha-insect toxin from the scorpion Buthus martensii Karsch.
Acta Crystallogr.,Sect.D, 59, 2003
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1KVN
 | | Solution Structure Of Protein SRP19 Of The Arhaeoglobus fulgidus Signal Recognition Particle, 10 Structures | | 分子名称: | SRP19 | | 著者 | Pakhomova, O.N, Deep, S, Huang, Q, Zwieb, C, Hinck, A.P. | | 登録日 | 2002-01-27 | | 公開日 | 2002-03-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of protein SRP19 of Archaeoglobus fulgidus signal recognition particle.
J.Mol.Biol., 317, 2002
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1OX1
 | | crystal structure of the bovine trypsin complex with a synthetic 11 peptide inhibitor | | 分子名称: | 11-mer peptide, CALCIUM ION, Trypsinogen, ... | | 著者 | Wu, G, Huang, Y, Zhu, G, Huang, Q, Tang, Y, Miyake, H, Kusunoki, M. | | 登録日 | 2003-03-31 | | 公開日 | 2004-05-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | crystal structure of the bovine trypsin complex with a synthetic 11 peptide inhibitor
To be published
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2MV6
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1T0L
 | | Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP, isocitrate, and calcium(2+) | | 分子名称: | CALCIUM ION, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, ... | | 著者 | Xu, X, Zhao, J, Peng, B, Huang, Q, Arnold, E, Ding, J. | | 登録日 | 2004-04-10 | | 公開日 | 2004-06-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity
J.Biol.Chem., 279, 2004
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1T09
 | | Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex NADP | | 分子名称: | Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Xu, X, Zhao, J, Peng, B, Huang, Q, Arnold, E, Ding, J. | | 登録日 | 2004-04-08 | | 公開日 | 2004-06-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity
J.Biol.Chem., 279, 2004
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1P0R
 | | Solution Structure of UBL5 a human Ubiquitin-Like Protein | | 分子名称: | ubiquitin-like 5 | | 著者 | McNally, T, Huang, Q, Janis, R.S, Liu, Z, Olejniczak, E.T, Reilly, R.M. | | 登録日 | 2003-04-10 | | 公開日 | 2003-10-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural analysis of UBL5, a novel ubiquitin-like modifier
Protein Sci., 12, 2003
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2ABO
 | | NMR structure of gamma herpesvirus 68 a viral Bcl-2 homolog | | 分子名称: | bcl-2 homolog | | 著者 | Loh, J, Huang, Q, Petros, A.M, Nettesheim, D, van Dyk, L.F, Labrada, L, Speck, S.H, Levine, B, Olejniczak, E.T, Virgin, H.W. | | 登録日 | 2005-07-15 | | 公開日 | 2006-05-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A surface groove essential for viral Bcl-2 function during chronic infection in vivo.
Plos Pathog., 1, 2005
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2L4R
 | | NMR solution structure of the N-terminal PAS domain of hERG | | 分子名称: | Potassium voltage-gated channel subfamily H member 2 | | 著者 | Gayen, N, Li, Q, Chen, A.S, Huang, Q, Raida, M, Kang, C. | | 登録日 | 2010-10-13 | | 公開日 | 2010-12-22 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of the N-terminal domain of hERG and its interaction with the S4-S5 linker.
Biochem.Biophys.Res.Commun., 403, 2010
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4HTX
 | | Crystal structure of PDE2 catalytic domain in complex with BAY60-7550 | | 分子名称: | 2-(3,4-dimethoxybenzyl)-7-[(2R,3R)-2-hydroxy-6-phenylhexan-3-yl]-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one, MAGNESIUM ION, ZINC ION, ... | | 著者 | Zhu, J, Huang, Q. | | 登録日 | 2012-11-02 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity.
J.Am.Chem.Soc., 135, 2013
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4HTZ
 | | Crystal structure of PDE2 catalytic domain in space group P1 | | 分子名称: | MAGNESIUM ION, ZINC ION, cGMP-dependent 3',5'-cyclic phosphodiesterase | | 著者 | Zhu, J, Huang, Q. | | 登録日 | 2012-11-02 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity.
J.Am.Chem.Soc., 135, 2013
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8W4F
 | | SARS-CoV-2 spike protein in complex with a trivalent nanobody | | 分子名称: | Spike glycoprotein, Tribody | | 著者 | Jiang, X.Y, Qian, J.Q, Zhu, H.X, Qin, Q, Huang, Q. | | 登録日 | 2023-08-24 | | 公開日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure-guided design of a trivalent nanobody cluster targeting SARS-CoV-2 spike protein.
Int.J.Biol.Macromol., 256, 2024
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7U3Q
 | | [4T7] Self-assembling tensegrity triangle with four turns of DNA per axis with R3 symmetry | | 分子名称: | DNA (29-MER), DNA (42-MER), DNA (5'-D(P*AP*CP*A)-3'), ... | | 著者 | Woloszyn, K, Vecchioni, S, Lu, B, Ma, Y, Seeman, N.C, Sha, R, Ohayon, Y.P, Huang, Q. | | 登録日 | 2022-02-28 | | 公開日 | 2022-09-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (9.32 Å) | | 主引用文献 | Augmented DNA Nanoarchitectures: A Structural Library of 3D Self-Assembling Tensegrity Triangle Variants.
Adv Mater, 34, 2022
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4MIW
 | | High-resolution structure of the N-terminal endonuclease domain of the Lassa virus L polymerase | | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L | | 著者 | Wallat, G.D, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C. | | 登録日 | 2013-09-02 | | 公開日 | 2014-03-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | High-resolution structure of the N-terminal endonuclease domain of the lassa virus L polymerase in complex with magnesium ions.
Plos One, 9, 2014
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2H40
 | | Crystal structure of the catalytic domain of unliganded PDE5 | | 分子名称: | MAGNESIUM ION, ZINC ION, cGMP-specific 3',5'-cyclic phosphodiesterase | | 著者 | Wang, H, Liu, Y, Huai, Q, Cai, J, Zoraghi, R, Francis, S.H, Corbin, J.D, Robinson, H, Xin, Z, Lin, G, Ke, H. | | 登録日 | 2006-05-23 | | 公開日 | 2006-06-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006
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3TKK
 | | Crystal Structure Analysis of a recombinant predicted acetamidase/ formamidase from the thermophile thermoanaerobacter tengcongensis | | 分子名称: | CALCIUM ION, Predicted acetamidase/formamidase, ZINC ION | | 著者 | Qian, M, Huang, Q, Wu, G, Lai, L, Tang, Y, Pei, J, Kusunoki, M. | | 登録日 | 2011-08-26 | | 公開日 | 2011-11-16 | | 最終更新日 | 2012-02-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Crystal Structure Analysis of a Recombinant Predicted Acetamidase/Formamidase from the Thermophile Thermoanaerobacter tengcongensis.
PROTEIN J., 31, 2012
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4GVE
 | | Tacaribe nucleoprotein structure | | 分子名称: | MAGNESIUM ION, Nucleoprotein, ZINC ION | | 著者 | Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C. | | 登録日 | 2012-08-30 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
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