8SLS

Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and ambient pressure (0.1 MPa)

Summary for 8SLS

Entry DOI	10.2210/pdb8sls/pdb
Descriptor	Tyrosine-protein phosphatase non-receptor type 5, SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	ptpn5, step, phosphatase, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	32802.21
Authors	Ebrahim, A.,Guerrero, L.,Riley, B.T.,Kim, M.,Huang, Q.,Finke, A.D.,Keedy, D.A. (deposition date: 2023-04-24, release date: 2023-06-21, Last modification date: 2023-09-27)
Primary citation	Guerrero, L.,Ebrahim, A.,Riley, B.T.,Kim, M.,Huang, Q.,Finke, A.D.,Keedy, D.A. Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase. Biorxiv, 2023 Cited by PubMed: 37205580 DOI: 10.1101/2023.05.02.538097 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.71 Å)

Structure validation