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8SLS

Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and ambient pressure (0.1 MPa)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase non-receptor type 5polymer28232518.01UniProt (P54829)
Pfam (PF00102)
Homo sapiens (human)Neural-specific protein-tyrosine phosphatase,Striatum-enriched protein-tyrosine phosphatase,STEP
2B, D
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4E
(A)
waterwater18.0149Chemie (HOH)
Sequence modifications
A: 256 - 537 (UniProt: P54829)
PDBExternal DatabaseDetails
Met 257Ala 281conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32518.0
Non-Polymers*Number of molecules3
Total formula weight284.2
All*Total formula weight32802.2
*Water molecules are not included.

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PDB entries from 2025-06-25

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