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6SJU
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BU of 6sju by Molmil
Human kallikrein 7 with aromatic coumarinic ester compound 3 covalently bound to H57
分子名称: (3-iodanylphenyl) 6-methyl-2-oxidanylidene-chromene-3-carboxylate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Kallikrein-7, ...
著者Hanke, S, Straeter, N.
登録日2019-08-13
公開日2020-05-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7.
J.Med.Chem., 63, 2020
6SHI
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BU of 6shi by Molmil
Human kallikrein 7 with aromatic coumarinic ester compound 2 covalently bound to H57
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-methyl-2-oxidanylidene-chromene-3-carboxylic acid, Kallikrein-7, ...
著者Hanke, S, Straeter, N.
登録日2019-08-06
公開日2020-05-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7.
J.Med.Chem., 63, 2020
6SHH
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BU of 6shh by Molmil
Human kallikrein 7 with aromatic coumarinic ester compound 1 covalently bound to H57
分子名称: (3-chlorophenyl) 6-methyl-2-oxidanylidene-chromene-3-carboxylate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Kallikrein-7, ...
著者Hanke, S, Straeter, N.
登録日2019-08-06
公開日2020-05-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7.
J.Med.Chem., 63, 2020
7ZL3
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BU of 7zl3 by Molmil
Signal peptide mimicry primes Sec61 for client-selective inhibition
分子名称: Cyclic depsipeptide signal peptide mimic, Protein transport protein Sec61 subunit alpha, Protein transport protein Sec61 subunit beta, ...
著者Rehan, S, Paavilainen O, V.
登録日2022-04-13
公開日2023-03-22
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Signal peptide mimicry primes Sec61 for client-selective inhibition.
Nat.Chem.Biol., 19, 2023
6Y4S
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BU of 6y4s by Molmil
Human kallikrein-related peptidase 7 (KLK7) in the unliganded state
分子名称: Kallikrein-7, SULFATE ION, TRIETHYLENE GLYCOL
著者Hanke, S, Strater, N.
登録日2020-02-23
公開日2020-05-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7.
J.Med.Chem., 63, 2020
5VF4
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BU of 5vf4 by Molmil
Thermus aquaticus variable protein (TaqVP) from diversity-generating retroelements (DGR)
分子名称: ACETATE ION, CALCIUM ION, Uncharacterized protein
著者Handa, S, Ghosh, P.
登録日2017-04-06
公開日2017-05-24
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystal structure of a Thermus aquaticus diversity-generating retroelement variable protein.
PLoS ONE, 14, 2019
7ZLO
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BU of 7zlo by Molmil
Crystal structure of SOCS2:ElonginB:ElonginC in complex with compound 12
分子名称: Elongin-B, Elongin-C, Suppressor of cytokine signaling 2, ...
著者Ramachandran, S, Ciulli, A, Makukhin, N.
登録日2022-04-15
公開日2023-04-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2.
Nat Commun, 14, 2023
7ZLP
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BU of 7zlp by Molmil
Crystal structure of SOCS2:ElonginB:ElonginC in complex with compound 9
分子名称: Elongin-B, Elongin-C, PHOSPHATE ION, ...
著者Ramachandran, S, Ciulli, A, Makukhin, N.
登録日2022-04-15
公開日2023-04-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2.
Nat Commun, 14, 2023
7ZLN
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BU of 7zln by Molmil
Crystal structure of SOCS2:ElonginB:ElonginC in complex with compound 11
分子名称: Elongin-B, Elongin-C, Suppressor of cytokine signaling 2, ...
著者Ramachandran, S, Ciulli, A, Makukhin, N.
登録日2022-04-15
公開日2023-04-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2.
Nat Commun, 14, 2023
7ZLS
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BU of 7zls by Molmil
co-crystal structure of SOCS2:ElonginB:ElonginC in complex with compound 13
分子名称: 1,2-ETHANEDIOL, Elongin-B, Elongin-C, ...
著者Ramachandran, S, Ciulli, A, Makukhin, N.
登録日2022-04-15
公開日2023-04-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2.
Nat Commun, 14, 2023
7ZLR
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BU of 7zlr by Molmil
Crystal structure of SOCS2:ElonginB:ElonginC in complex with compound 13
分子名称: Elongin-B, Elongin-C, Suppressor of cytokine signaling 2, ...
著者Ramachandran, S, Ciulli, A, Makukhin, N.
登録日2022-04-15
公開日2023-04-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2.
Nat Commun, 14, 2023
7ZLM
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BU of 7zlm by Molmil
Crystal structure of SOCS2:ElonginB:ElonginC in complex with compound MN551
分子名称: Elongin-B, Elongin-C, Suppressor of cytokine signaling 2, ...
著者Ramachandran, S, Ciulli, A, Makukhin, N.
登録日2022-04-15
公開日2023-04-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2.
Nat Commun, 14, 2023
5C6T
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BU of 5c6t by Molmil
Crystal structure of HCMV glycoprotein B in complex with 1G2 Fab
分子名称: 1G2 Fab heavy chain, 1G2 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chandramouli, S, Ciferri, C, Settembre, E.C, Carfi, A.
登録日2015-06-23
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody.
Nat Commun, 6, 2015
6LKB
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BU of 6lkb by Molmil
Crystal Structure of the peptidylprolyl isomerase domain of Arabidopsis thaliana CYP71.
分子名称: COBALT (II) ION, GLYCEROL, PHOSPHATE ION, ...
著者Lakhanpal, S, Jobichen, C, Swaminathan, K.
登録日2019-12-18
公開日2020-12-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献Structural and functional analyses of the PPIase domain of Arabidopsis thaliana CYP71 reveal its catalytic activity toward histone H3.
Febs Lett., 595, 2021
5GOU
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BU of 5gou by Molmil
Structure of a 16-mer protein nanocage fabricated from its 24-mer analogue by subunit interface redesign
分子名称: Ferritin heavy chain
著者Zhang, S, Zang, J, Wang, W, Wang, H, Zhao, G.
登録日2016-07-29
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Conversion of the Native 24-mer Ferritin Nanocage into Its Non-Native 16-mer Analogue by Insertion of Extra Amino Acid Residues.
Angew. Chem. Int. Ed. Engl., 55, 2016
5H32
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BU of 5h32 by Molmil
Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0
分子名称: C10 IgG heavy chain variable region, C10 IgG light chain variable region, structural protein E
著者Zhang, S, Kostyuchenko, V, Ng, T.-S, Lok, S.-M.
登録日2016-10-20
公開日2016-11-30
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
5H37
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BU of 5h37 by Molmil
Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, C10 IgG light chain variable region, ...
著者Zhang, S, Kostyuchenko, V, Ng, T.-S, Lim, X.-N, Ooi, J.S.G, Lambert, S, Tan, T.Y, Widman, D, Shi, J, Baric, R.S, Lok, S.-M.
登録日2016-10-20
公開日2016-11-30
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
5H30
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BU of 5h30 by Molmil
Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5
分子名称: IgG C10 heavy chain, IgG C10 light chain, structural protein E, ...
著者Zhang, S, Kostyuchenko, V, Ng, T.-S, Lok, S.-M.
登録日2016-10-19
公開日2016-11-30
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
5GN8
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BU of 5gn8 by Molmil
Structure of a 48-mer protein nanocage fabricated from its 24-mer analogue by subunit interface redesign
分子名称: CALCIUM ION, Ferritin heavy chain
著者Zhang, S, Zang, J, Zhao, G, Mikami, B.
登録日2016-07-19
公開日2016-12-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献"Silent" Amino Acid Residues at Key Subunit Interfaces Regulate the Geometry of Protein Nanocages
ACS Nano, 10, 2016
1HZ3
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BU of 1hz3 by Molmil
ALZHEIMER'S DISEASE AMYLOID-BETA PEPTIDE (RESIDUES 10-35)
分子名称: A-BETA AMYLOID
著者Zhang, S, Iwata, K, Lachenmann, M.J, Peng, J.W, Li, S, Stimson, E.R, Lu, Y, Felix, A.M, Maggio, J.E, Lee, J.P.
登録日2001-01-23
公開日2001-01-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The Alzheimer's peptide a beta adopts a collapsed coil structure in water.
J.Struct.Biol., 130, 2000
5AEI
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BU of 5aei by Molmil
Designed Armadillo repeat protein YIIIM5AII in complex with peptide (KR)5
分子名称: ACETATE ION, CALCIUM ION, DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII, ...
著者Hansen, S, Tremmel, D, Madhurantakam, C, Reichen, C, Mittl, P, Plueckthun, A.
登録日2015-08-31
公開日2016-03-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structure and Energetic Contributions of a Designed Modular Peptide-Binding Protein with Picomolar Affinity.
J.Am.Chem.Soc., 138, 2016
2WGU
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BU of 2wgu by Molmil
Structure of human adenovirus serotype 37 fibre head in complex with a sialic acid derivative, O-Methyl 5-N- methoxycarbonyl -3,5-dideoxy- D-glycero-a-D-galacto-2-nonulopyranosylonic acid
分子名称: 3,5-dideoxy-5-[(methoxycarbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, FIBER PROTEIN, ZINC ION
著者Johansson, S, Nilsson, E, Qian, W, Guilligay, D, Crepin, T, Cusack, S, Arnberg, N, Elofsson, M.
登録日2009-04-27
公開日2009-11-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design, Synthesis, and Evaluation of N-Acyl Modified Sialic Acids as Inhibitors of Adenoviruses Causing Epidemic Keratoconjunctivitis.
J.Med.Chem., 52, 2009
5IOO
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BU of 5ioo by Molmil
Accommodation of massive sequence variation in Nanoarchaeota by the C-type lectin fold
分子名称: AvpA, MAGNESIUM ION
著者Handa, S, Paul, B, Miller, J, Valentine, D, Ghosh, P.
登録日2016-03-08
公開日2016-11-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.521 Å)
主引用文献Conservation of the C-type lectin fold for accommodating massive sequence variation in archaeal diversity-generating retroelements.
Bmc Struct.Biol., 16, 2016
5BN4
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BU of 5bn4 by Molmil
Structure of a unique ATP synthase NeqA-NeqB in complex with ANP from Nanoarcheaum equitans
分子名称: MAGNESIUM ION, NEQ263, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J.
登録日2015-05-25
公開日2015-09-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.699 Å)
主引用文献Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015
5BN3
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BU of 5bn3 by Molmil
Structure of a unique ATP synthase NeqA-NeqB in complex with ADP from Nanoarcheaum equitans
分子名称: 1,4-DIETHYLENE DIOXIDE, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
著者Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J.
登録日2015-05-25
公開日2015-09-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015

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