6Y4S
Human kallikrein-related peptidase 7 (KLK7) in the unliganded state
Summary for 6Y4S
Entry DOI | 10.2210/pdb6y4s/pdb |
Descriptor | Kallikrein-7, TRIETHYLENE GLYCOL, SULFATE ION, ... (4 entities in total) |
Functional Keywords | kallikrein 7, hk7, serine protease, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 74938.53 |
Authors | Hanke, S.,Strater, N. (deposition date: 2020-02-23, release date: 2020-05-20, Last modification date: 2024-01-24) |
Primary citation | Hanke, S.,Tindall, C.A.,Pippel, J.,Ulbricht, D.,Pirotte, B.,Reboud-Ravaux, M.,Heiker, J.T.,Strater, N. Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7. J.Med.Chem., 63:5723-5733, 2020 Cited by PubMed: 32374603DOI: 10.1021/acs.jmedchem.9b01806 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.23 Å) |
Structure validation
Download full validation report