2WGU

Structure of human adenovirus serotype 37 fibre head in complex with a sialic acid derivative, O-Methyl 5-N- methoxycarbonyl -3,5-dideoxy- D-glycero-a-D-galacto-2-nonulopyranosylonic acid

Summary for 2WGU

Entry DOI	10.2210/pdb2wgu/pdb
Related	1UXA 1UXB 1UXE 2J12 2WGT
Descriptor	FIBER PROTEIN, 3,5-dideoxy-5-[(methoxycarbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, ZINC ION, ... (4 entities in total)
Functional Keywords	sialic acid, viral protein, conjunctivitis, daf, ad37, cd46, receptor, neuraminic acid
Biological source	HUMAN ADENOVIRUS 37
Total number of polymer chains	3
Total formula weight	66321.64
Authors	Johansson, S.,Nilsson, E.,Qian, W.,Guilligay, D.,Crepin, T.,Cusack, S.,Arnberg, N.,Elofsson, M. (deposition date: 2009-04-27, release date: 2009-11-24, Last modification date: 2023-12-13)
Primary citation	Johansson, S.,Nilsson, E.,Qian, W.,Guilligay, D.,Crepin, T.,Cusack, S.,Arnberg, N.,Elofsson, M. Design, Synthesis, and Evaluation of N-Acyl Modified Sialic Acids as Inhibitors of Adenoviruses Causing Epidemic Keratoconjunctivitis. J.Med.Chem., 52:3666-, 2009 Cited by PubMed: 19456100 DOI: 10.1021/JM801609S PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation