3T5T
 
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6F7A
 | | Gloeobacter Ligand-gated Ion Channel (GLIC) closed state crystallized in an ultra-swollen lipidic mesophase | | 分子名称: | Proton-gated ion channel | | 著者 | Martiel, I, Zabara, A, Chong, J.Y.T, Stark, L, Cromer, B, Dummond, C.J, Mezzenga, R. | | 登録日 | 2017-12-07 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (6 Å) | | 主引用文献 | Design of ultra-swollen lipidic mesophases for the crystallization of membrane proteins with large extracellular domains.
Nat Commun, 9, 2018
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3T7D
 | | Vall from streptomyces hygroscopicus in complex with trehalose | | 分子名称: | IMIDAZOLE, MAGNESIUM ION, Putative glycosyltransferase, ... | | 著者 | Zhang, H, Zheng, L, Qian, H, Chen, J. | | 登録日 | 2011-07-29 | | 公開日 | 2012-08-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for the substrate specificity of ValL
To be Published
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8RBQ
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4CBK
 | | The c-ring ion binding site of the ATP synthase from Bacillus pseudofirmus OF4 is adapted to alkaliphilic cell physiology | | 分子名称: | ATP SYNTHASE SUBUNIT C, DODECYL-BETA-D-MALTOSIDE, SODIUM ION, ... | | 著者 | Preiss, L, Yildiz, O, Meier, T. | | 登録日 | 2013-10-14 | | 公開日 | 2014-04-23 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | The C-Ring Ion-Binding Site of the ATP Synthase from Bacillus Pseudofirmus of4 is Adapted to Alkaliphilic Lifestyle.
Mol.Microbiol., 92, 2014
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8RGZ
 | | Trimeric HSV-1F gB ectodomain in postfusion conformation with three bound HDIT101 Fab molecules. | | 分子名称: | Envelope glycoprotein B, HDIT101 Fab heavy chain, HDIT101 Fab light chain | | 著者 | Kalbermatter, D, Seyfizadeh, N, Imhof, T, Ries, M, Mueller, C, Jenner, L, Blumenschein, E, Yendrzheyevskiy, A, Moog, K, Eckert, D, Engel, R, Diebolder, P, Chami, M, Krauss, J, Schaller, T, Arndt, M. | | 登録日 | 2023-12-14 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus.
J.Biomed.Sci., 31, 2024
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8UTT
 | | KIF1A[1-393] P305L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | | 登録日 | 2023-10-31 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM unveils kinesin KIF1A's processivity mechanism and the impact of its pathogenic variant P305L.
Nat Commun, 15, 2024
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8V6T
 | | Crystal structure of EcThsB2 | | 分子名称: | BROMIDE ION, Molecular chaperone Tir | | 著者 | Shi, Y, Masic, V, Mosaiab, T, Goulart, C.C, Hartley-Tassell, L, Sorbello, M, Vasquez, E, Mishra, B.P, Holt, S, Gu, W, Kobe, B, Ve, T. | | 登録日 | 2023-12-02 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structural characterization of macro domain-containing Thoeris antiphage defense systems.
Sci Adv, 10, 2024
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5MT3
 | | Human insulin in complex with serotonin and arginine | | 分子名称: | ARGININE, CHLORIDE ION, Insulin, ... | | 著者 | Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. | | 登録日 | 2017-01-06 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.
J. Biol. Chem., 292, 2017
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1P7C
 | | Crystal Structure of HSV1-TK complexed with TP5A | | 分子名称: | P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, SULFATE ION, THYMIDINE, ... | | 著者 | Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. | | 登録日 | 2003-05-01 | | 公開日 | 2003-11-04 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases.
Structure, 11, 2003
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5Y61
 | | YfiB-YfiR complexed with GMP | | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, YfiB, YfiR | | 著者 | Zhou, L, Xu, M, Jiang, T. | | 登録日 | 2017-08-10 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Structural insights into the functional role of GMP in modulating the YfiBNR system
Biochem. Biophys. Res. Commun., 493, 2017
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5MT9
 | | Human insulin in complex with serotonin and arginine | | 分子名称: | ARGININE, CHLORIDE ION, Insulin, ... | | 著者 | Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. | | 登録日 | 2017-01-07 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.
J. Biol. Chem., 292, 2017
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5MTL
 | | Crystal structure of an amyloidogenic light chain | | 分子名称: | light chain dimer,IGL@ protein,IGL@ protein | | 著者 | Oberti, L, Rognoni, P, Russo, R, Bacarizo, J, Bolognesi, M, Ricagno, S. | | 登録日 | 2017-01-10 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
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1F3L
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1F4L
 | | CRYSTAL STRUCTURE OF THE E.COLI METHIONYL-TRNA SYNTHETASE COMPLEXED WITH METHIONINE | | 分子名称: | METHIONINE, METHIONYL-TRNA SYNTHETASE, ZINC ION | | 著者 | Serre, L, Verdon, G, Chonowski, T, Hervouet, N, Zelwer, C. | | 登録日 | 2000-06-08 | | 公開日 | 2001-03-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | How methionyl-tRNA synthetase creates its amino acid recognition pocket upon L-methionine binding.
J.Mol.Biol., 306, 2001
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8BJT
 | | Structure of human PLK1 in complex with 2-Allyl-1-[6-(1-hydroxy-1-methyl-ethyl)-pyridin-2-yl]-6-[4-(4-methyl-piperazin-1-yl)-phenylamino]-1,2-dihydro-pyrazolo[3,4-d]pyrimidin-3-one | | 分子名称: | 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, ACETATE ION, Serine/threonine-protein kinase PLK1, ... | | 著者 | Musil, D, Liu-Bujalski, L. | | 登録日 | 2022-11-06 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.188 Å) | | 主引用文献 | Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with Myelosuppression.
Acs Med.Chem.Lett., 14, 2023
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8RH0
 | | Trimeric HSV-1F gB ectodomain in postfusion conformation with three bound HDIT102 Fab molecules. | | 分子名称: | Envelope glycoprotein B, HDIT102 Fab heavy chain | | 著者 | Kalbermatter, D, Seyfizadeh, N, Imhof, T, Ries, M, Mueller, C, Jenner, L, Blumenschein, E, Yendrzheyevskiy, A, Moog, K, Eckert, D, Engel, R, Diebolder, P, Chami, M, Krauss, J, Schaller, T, Arndt, M. | | 登録日 | 2023-12-14 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus.
J.Biomed.Sci., 31, 2024
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5Y7N
 | | Crystal structure of AKR1B10 in complex with NADP+ and Androst-4-ene-3-beta-6-alpha-diol | | 分子名称: | (3S,6S,8S,9S,10R,13S,14R)-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6-diol, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Hong, Z, Liping, Z, Cuiyun, L, Wei, Z. | | 登録日 | 2017-08-17 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural determinants for the inhibition of AKR1B10 by steroids
To Be Published
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5MVO
 | | FoxE P43212 crystal structure of Rhodopseudomonas ferrooxidans SW2 putative iron oxidase | | 分子名称: | COPPER (II) ION, FoxE, HEME C, ... | | 著者 | Pereira, L, Saraiva, I.H, Oliveira, A.S, Soares, C, Gomes, R.O, Frazao, C. | | 登録日 | 2017-01-17 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.668 Å) | | 主引用文献 | Crystallization and preliminary crystallographic studies of FoxE from Rhodobacter ferrooxidans SW2, an Fe(II) oxidoreductase involved in photoferrotrophy.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 68, 2012
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1F57
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8B4H
 | | IstA transposase cleaved donor complex | | 分子名称: | DNA (55-MER) / right IS21 transposon end (insertion sequence IS5376), DNA (57-MER) / right IS21 transposon end (insertion sequence IS5376), MAGNESIUM ION, ... | | 著者 | Spinola-Amilibia, M, de la Gandara, A, Araujo-Bazan, L, Berger, J.M, Arias-Palomo, E. | | 登録日 | 2022-09-20 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | IS21 family transposase cleaved donor complex traps two right-handed superhelical crossings.
Nat Commun, 14, 2023
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8UTY
 | | KIF1A[1-393] P364L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | | 登録日 | 2023-10-31 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM unveils kinesin KIF1A's processivity mechanism and the impact of its pathogenic variant P305L.
Nat Commun, 15, 2024
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8V6R
 | | Crystal structure of EcThsA in complex with ADPR | | 分子名称: | Thoeris protein ThsA Macro domain-containing protein, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | | 著者 | Shi, Y, Masic, V, Mosaiab, T, Goulart, C.C, Hartley-Tassell, L, Sorbello, M, Vasquez, E, Mishra, B.P, Holt, S, Gu, W, Kobe, B, Ve, T. | | 登録日 | 2023-12-02 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Structural characterization of macro domain-containing Thoeris antiphage defense systems.
Sci Adv, 10, 2024
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8S1P
 | | YlmH bound to PtRNA-50S | | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | | 登録日 | 2024-02-15 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (1.96 Å) | | 主引用文献 | A role for the S4-domain containing protein YlmH in ribosome-associated quality control in Bacillus subtilis.
Nucleic Acids Res., 52, 2024
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5MWI
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