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5MRC
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BU of 5mrc by Molmil
Structure of the yeast mitochondrial ribosome - Class A
分子名称: 15S ribosomal RNA, 21S ribosomal RNA, GUANOSINE-5'-DIPHOSPHATE, ...
著者Desai, N, Brown, A, Amunts, A, Ramakrishnan, V.
登録日2016-12-22
公開日2017-02-15
最終更新日2018-02-07
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献The structure of the yeast mitochondrial ribosome.
Science, 355, 2017
5TB7
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BU of 5tb7 by Molmil
Structure of nitrite reductase AniA from Neisseria gonorrhoeae, space group P212121
分子名称: COPPER (II) ION, Nitrite reductase, PHOSPHATE ION
著者Hamza, A, Williamson, Z.A, Reed, R.W, Sikora, A.E, Korotkov, K.V.
登録日2016-09-11
公開日2017-02-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Peptide Inhibitors Targeting the Neisseria gonorrhoeae Pivotal Anaerobic Respiration Factor AniA.
Antimicrob. Agents Chemother., 61, 2017
5MRE
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BU of 5mre by Molmil
Structure of the yeast mitochondrial ribosome - Class B
分子名称: 15S ribosomal RNA, 21S ribosomal RNA, GUANOSINE-5'-DIPHOSPHATE, ...
著者Desai, N, Brown, A, Amunts, A, Ramakrishnan, V.
登録日2016-12-22
公開日2017-02-15
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献The structure of the yeast mitochondrial ribosome.
Science, 355, 2017
6PA6
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BU of 6pa6 by Molmil
ECAII(T89V,K162T) MUTANT IN COMPLEX WITH L-ASN AT PH 8.3 in space group C2
分子名称: ASPARAGINE, IMIDAZOLE, L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-06-11
公開日2019-09-04
最終更新日2019-10-02
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
1DY3
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BU of 1dy3 by Molmil
Ternary complex of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogue.
分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 7,8-DIHYDRO-6-HYDROXYMETHYL-7-METHYL-7-[2-PHENYLETHYL]-PTERIN, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Stammers, D.K, Achari, A, Somers, D.O, Bryant, P.K, Rosemond, J, Scott, D.L, Champness, J.N.
登録日2000-01-21
公開日2000-08-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献2.0A X-Ray Structure of the Ternary Complex of 7,8-Dihydro-6-Hydroxymethylpterinpyrophosphokinase from Escherichia Coli with ATP and a Substrate Analogue
FEBS Lett., 456, 1999
6SYP
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BU of 6syp by Molmil
Human DHODH bound to inhibitor IPP/CNRS-A017
分子名称: 2-[4-[2,6-bis(fluoranyl)phenoxy]-5-methyl-3-propan-2-yloxy-pyrazol-1-yl]-5-cyclopropyl-3-fluoranyl-pyridine, Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, ...
著者Kraemer, A, Janin, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2019-09-30
公開日2019-10-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor
Eur.J.Med.Chem., 208, 2020
1DZ1
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BU of 1dz1 by Molmil
Mouse HP1 (M31) C terminal (shadow chromo) domain
分子名称: MODIFIER 1 PROTEIN
著者Brasher, S.V, Smith, B.O, Fogh, R.H, Nietlispach, D, Thiru, A, Nielsen, P.R, Broadhurst, R.W, Ball, L.J, Murzina, N, Laue, E.D.
登録日2000-02-11
公開日2000-04-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Structure of Mouse Hp1 Suggests a Unique Mode of Single Peptide Recognition by the Shadow Chromo Domain Dimer
Embo J., 19, 2000
7R55
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BU of 7r55 by Molmil
B-trefoil lectin from Salpingoeca rosetta in complex with Gb3
分子名称: 1,2-ETHANEDIOL, Sarol-1, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
著者Notova, S, Varrot, A.
登録日2022-02-10
公開日2022-09-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3.
Commun Biol, 5, 2022
6PAA
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BU of 6paa by Molmil
E. coli L-asparaginase II mutant (T12V) in complex with L-Asp at pH 5.5
分子名称: ASPARTIC ACID, L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-06-11
公開日2019-09-04
最終更新日2019-10-02
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
1DZC
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BU of 1dzc by Molmil
High resolution structure of acidic fibroblast growth factor. Mutant FGF-4-ALA-(24-154), 24 NMR structures
分子名称: FIBROBLAST GROWTH FACTOR 1
著者Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G.
登録日2000-02-24
公開日2000-03-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor
Biochemistry, 39, 2000
8PFU
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BU of 8pfu by Molmil
X-ray structure of the adduct formed upon reaction of Lysozyme with K3[Ru2(CO3)4] in condition A
分子名称: 6,8-bis(4-fluorophenyl)-1,5-bis(oxidanyl)-2,4-dioxa-6,8-diaza-1$l^{4},5$l^{4}-diruthenabicyclo[3.3.0]octan-3-one, CARBONATE ION, Lysozyme C, ...
著者Teran, A, Ferraro, G, Merlino, A.
登録日2023-06-16
公開日2023-07-19
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Charge effect in protein metalation reactions by diruthenium complexes
Inorg Chem Front, 2023
3UY9
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BU of 3uy9 by Molmil
Bovine trypsin variant X(tripleGlu217Phe227) in complex with small molecule inhibitor
分子名称: BENZAMIDINE, CALCIUM ION, CHLORIDE ION, ...
著者Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T.
登録日2011-12-06
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues.
Biol.Chem., 395, 2014
3SMR
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BU of 3smr by Molmil
Crystal structure of human WD repeat domain 5 with compound
分子名称: 1,2-ETHANEDIOL, 2-chloro-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide, UNKNOWN ATOM OR ION, ...
著者Dong, A, Dombrovski, L, Wasney, G.A, Tempel, W, Senisterra, G, Bolshan, Y, Smil, D, Nguyen, K.T, Hajian, T, Poda, G, Al-Awar, R, Bountra, C, Weigelt, J, Edwards, A.M, Brown, P.J, Schapira, M, Arrowsmith, C.H, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC)
登録日2011-06-28
公開日2011-08-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5.
Biochem. J., 449, 2013
6ON3
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BU of 6on3 by Molmil
A substrate bound structure of L-DOPA dioxygenase from Streptomyces sclerotialus
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,4-DIHYDROXYPHENYLALANINE, FE (II) ION, ...
著者Wang, Y, Shin, I, Fu, Y, Colabroy, K, Liu, A.
登録日2019-04-19
公開日2019-06-26
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal Structures of L-DOPA Dioxygenase fromStreptomyces sclerotialus.
Biochemistry, 58, 2019
5T80
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BU of 5t80 by Molmil
Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2 and phosphatidic acid (06:0 PA)
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, ...
著者Irimia, A, Wilson, I.A.
登録日2016-09-06
公開日2017-03-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
1M70
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BU of 1m70 by Molmil
Crystal structure of oxidized recombinant cytochrome c4 from Pseudomonas stutzeri
分子名称: Cytochrome c4, GLYCEROL, HEME C
著者Noergaard, A, Harris, P, Larsen, S, Christensen, H.E.M.
登録日2002-07-18
公開日2003-09-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural comparison of recombinant Pseudomonas stutzeri cytochrome c4 in two oxidation states
To be Published
8PFV
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BU of 8pfv by Molmil
X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(DAniF)(O2CCH3)3] in condition A
分子名称: 9,11-bis(4-methoxyphenyl)-3,7-dimethyl-2,4,6,8-tetraoxa-9,11-diaza-1$l^{4},5$l^{4}-diruthenatricyclo[3.3.3.0^{1,5}]undecane, CHLORIDE ION, Lysozyme C, ...
著者Teran, A, Ferraro, G, Merlino, A.
登録日2023-06-16
公開日2023-07-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Charge effect in protein metalation reactions by diruthenium complexes
Inorg Chem Front, 2023
1E0A
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BU of 1e0a by Molmil
Cdc42 complexed with the GTPase binding domain of p21 activated kinase
分子名称: Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Morreale, A, Venkatesan, M, Mott, H.R, Owen, D, Nietlispach, D, Lowe, P.N, Laue, E.D.
登録日2000-03-16
公開日2000-04-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of Cdc42 Bound to the Gtpase Binding Domian of Pak
Nat.Struct.Biol., 7, 2000
8PFT
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BU of 8pft by Molmil
X-ray structure of the adduct formed upon reaction of Lysozyme with K2[Ru2(D-p-FPhF)(CO3)3] in condition A
分子名称: 6,8-bis(4-fluorophenyl)-1,5-bis(oxidanyl)-2,4-dioxa-6,8-diaza-1$l^{4},5$l^{4}-diruthenabicyclo[3.3.0]octan-3-one, CHLORIDE ION, Lysozyme C, ...
著者Teran, A, Ferraro, G, Merlino, A.
登録日2023-06-16
公開日2023-07-19
実験手法X-RAY DIFFRACTION (1.304 Å)
主引用文献Charge effect in protein metalation reactions by diruthenium complexes
Inorg Chem Front, 2023
6SEZ
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BU of 6sez by Molmil
X-ray structure of the gold/lysozyme adduct formed upon 24h exposure of protein crystals to compound 1
分子名称: 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ...
著者Ferraro, G, Giorgio, A, Merlino, A.
登録日2019-07-30
公開日2019-09-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Protein-mediated disproportionation of Au(i): insights from the structures of adducts of Au(iii) compounds bearing N,N-pyridylbenzimidazole derivatives with lysozyme.
Dalton Trans, 48, 2019
6ONO
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BU of 6ono by Molmil
Complex structure of WhiB1 and region 4 of SigA in C2221 space group
分子名称: DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, RNA polymerase sigma factor SigA, ...
著者Wan, T, Li, S.R, Beltran, D.G, Schacht, A, Becker, D.C, Zhang, L.M.
登録日2019-04-22
公開日2019-11-27
最終更新日2020-01-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis of non-canonical transcriptional regulation by the sigma A-bound iron-sulfur protein WhiB1 in M. tuberculosis.
Nucleic Acids Res., 48, 2020
8PFY
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BU of 8pfy by Molmil
X-ray structure of the adduct formed upon reaction of Lysozyme with K2[Ru2(DAniF)(CO3)3] in condition B
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Lysozyme C, ...
著者Teran, A, Ferraro, G, Merlino, A.
登録日2023-06-16
公開日2023-07-19
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Charge effect in protein metalation reactions by diruthenium complexes
Inorg Chem Front, 2023
8PKP
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BU of 8pkp by Molmil
Cryo-EM structure of the apo Anaphase-promoting complex/cyclosome (APC/C) at 3.2 Angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D.
登録日2023-06-27
公開日2023-07-19
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1
To Be Published
1M8O
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BU of 1m8o by Molmil
Platelet integrin alfaIIb-beta3 cytoplasmic domain
分子名称: platelet integrin alfaIIb subunit: cytoplasmic domain, platelet integrin beta3 subunit: cytoplasmic domain
著者Vinogradova, O, Velyvis, A, Velyviene, A, Hu, B, Haas, T, Plow, E.F, Qin, J.
登録日2002-07-25
公開日2002-09-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A Structural mechanism of integrin alfaiib beta3 "Inside-out" Activation as regulated by its cytoplasmic face.
Cell(Cambridge,Mass.), 110, 2002
8PFW
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BU of 8pfw by Molmil
X-ray structure of the adduct formed upon reaction of Lysozyme with K2[Ru2(DAniF)(CO3)3] in condition A
分子名称: CHLORIDE ION, K2[Ru2(DAniF)(CO3)3], Lysozyme C, ...
著者Teran, A, Ferraro, G, Merlino, A.
登録日2023-06-16
公開日2023-07-19
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Charge effect in protein metalation reactions by diruthenium complexes
Inorg Chem Front, 2023

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