1M8O
Platelet integrin alfaIIb-beta3 cytoplasmic domain
Summary for 1M8O
Entry DOI | 10.2210/pdb1m8o/pdb |
Descriptor | platelet integrin alfaIIb subunit: cytoplasmic domain, platelet integrin beta3 subunit: cytoplasmic domain (2 entities in total) |
Functional Keywords | alfa helix, platelet, membrane protein |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P08514 P05106 |
Total number of polymer chains | 2 |
Total formula weight | 7981.85 |
Authors | Vinogradova, O.,Velyvis, A.,Velyviene, A.,Hu, B.,Haas, T.,Plow, E.F.,Qin, J. (deposition date: 2002-07-25, release date: 2002-09-18, Last modification date: 2024-05-22) |
Primary citation | Vinogradova, O.,Velyvis, A.,Velyviene, A.,Hu, B.,Haas, T.A.,Plow, E.F.,Qin, J. A Structural mechanism of integrin alfaiib beta3 "Inside-out" Activation as regulated by its cytoplasmic face. Cell(Cambridge,Mass.), 110:587-597, 2002 Cited by PubMed: 12230976DOI: 10.1016/S0092-8674(02)00906-6 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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