1M8O

Platelet integrin alfaIIb-beta3 cytoplasmic domain

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005178	molecular_function	integrin binding
B	0007155	biological_process	cell adhesion
B	0007229	biological_process	integrin-mediated signaling pathway
B	0008305	cellular_component	integrin complex
B	0070527	biological_process	platelet aggregation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	46
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
B	LYS21-THR67

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:O54890

Chain	Residue	Details
B	THR46

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:19141530, ECO:0007744|PubMed:18088087

Chain	Residue	Details
B	TYR52

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by PDPK1 and PKB/AKT1; in vitro => ECO:0000269|PubMed:10896934

Chain	Residue	Details
B	THR58

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:8631894

Chain	Residue	Details
B	TYR64

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