7R55

B-trefoil lectin from Salpingoeca rosetta in complex with Gb3

This is a non-PDB format compatible entry.

Summary for 7R55

• Entry DOI: 10.2210/pdb7r55/pdb
• Descriptor: Sarol-1, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: lectin, gb3, b-trefoil, pore forming lectin, sugar binding protein
• Biological source: Salpingoeca rosetta
• Total number of polymer chains: 2
• Total formula weight: 75115.39

Authors

Notova, S.,Varrot, A. (deposition date: 2022-02-10, release date: 2022-09-14, Last modification date: 2024-01-31)

• Primary citation: Notova, S.,Bonnardel, F.,Rosato, F.,Siukstaite, L.,Schwaiger, J.,Lim, J.H.,Bovin, N.,Varrot, A.,Ogawa, Y.,Romer, W.,Lisacek, F.,Imberty, A.; The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3.; Commun Biol, 5:954-954, 2022; PubMed: 36097056; DOI: 10.1038/s42003-022-03869-w

Experimental method

X-RAY DIFFRACTION (1.84 Å)