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3O53
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Crystal Structure of LRIM1 leucine-rich repeat domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, ...
著者Baxter, R.H.G, Steinert, S, Chelliah, Y, Volohonsky, G, Levashina, E.A, Deisenhofer, J.
登録日2010-07-27
公開日2010-09-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae.
Proc.Natl.Acad.Sci.USA, 107, 2010
3O6N
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Crystal Structure of APL1 leucine-rich repeat domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, APL1
著者Baxter, R.H.G, Steinert, S, Chelliah, Y, Volohonsky, G, Levashina, E.A, Deisenhofer, J.
登録日2010-07-29
公開日2010-09-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XIM
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BU of 2xim by Molmil
ARGININE RESIDUES AS STABILIZING ELEMENTS IN PROTEINS
分子名称: D-XYLOSE ISOMERASE, MAGNESIUM ION, Xylitol
著者Mrabet, N.T, Van Denbroek, A, Van Den Brande, I, Stanssens, P, Laroche, Y, Lambeir, A.-M, Matthyssens, G, Jenkins, J, Chiadmi, M, Vantilbeurgh, H, Rey, F, Janin, J, Quax, W.J, Lasters, I, Demaeyer, M, Wodak, S.J.
登録日1991-05-29
公開日1993-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Arginine residues as stabilizing elements in proteins.
Biochemistry, 31, 1992
7C5D
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BU of 7c5d by Molmil
Crystal structure of TRF2 TRFH domain in complex with a MCPH1 peptide
分子名称: GLYCEROL, Microcephalin, Telomeric repeat-binding factor 2
著者Xiong, X, Chen, Y.
登録日2020-05-19
公開日2020-10-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly.
Nat Commun, 11, 2020
2ME4
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BU of 2me4 by Molmil
HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle
分子名称: Envelope glycoprotein gp160
著者Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME1
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BU of 2me1 by Molmil
HIV-1 gp41 clade B double alanine mutant Membrane Proximal External Region peptide in DPC micelle
分子名称: Gp41
著者Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME2
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BU of 2me2 by Molmil
HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle
分子名称: Envelope glycoprotein gp160
著者Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME3
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BU of 2me3 by Molmil
HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle
分子名称: Envelope glycoprotein gp160
著者Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
7E1A
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BU of 7e1a by Molmil
Human bile salt exporter ABCB11 in complex with taurocholate
分子名称: Bile salt export pump, TAUROCHOLIC ACID
著者Wang, L, How, W.T, Chen, Y.
登録日2021-02-01
公開日2022-02-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets.
Cell Res., 32, 2022
5TOP
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BU of 5top by Molmil
Atomic Resolution X-Ray Crystal Structure of a Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with CTX-M-14 S70G Beta-Lactamase
分子名称: Beta-lactamase, POTASSIUM ION, RUTHENIUM ION, ...
著者Lewandowski, E.M, Chen, Y.
登録日2016-10-18
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Mechanisms of proton relay and product release by Class A beta-lactamase at ultrahigh resolution.
FEBS J., 285, 2018
5TOY
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BU of 5toy by Molmil
X-Ray Crystal Structure of Ruthenocene Conjugated Penicilloate and Penilloate Products in Complex with CTX-M-14 E166A Beta-Lactamase
分子名称: Beta-lactamase, PHOSPHATE ION, POTASSIUM ION, ...
著者Lewandowski, E.M, Chen, Y.
登録日2016-10-19
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Mechanisms of proton relay and product release by Class A beta-lactamase at ultrahigh resolution.
FEBS J., 285, 2018
7EHW
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BU of 7ehw by Molmil
BRD4-BD1 in complex with LT-642-602
分子名称: 1-[4-ethyl-2-methyl-5-(6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4
著者Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y.
登録日2021-03-30
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献BRD4-BD1 in complex with LT-642-602
To Be Published
7EHY
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BU of 7ehy by Molmil
BRD4-BD1 in complex with LT-448-138
分子名称: 1-[2,4-dimethyl-5-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4
著者Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y.
登録日2021-03-30
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献BRD4-BD1 in complex with LT-642-602
To Be Published
7EIG
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BU of 7eig by Molmil
BRD4-BD1 in complex with LT-730-903
分子名称: 1-[5-(5-azanyl-1H-benzimidazol-2-yl)-2-methyl-4-phenyl-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4
著者Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y.
登録日2021-03-31
公開日2022-04-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献BRD4-BD1 in complex with LT-730-903
To Be Published
7EIK
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BU of 7eik by Molmil
RD4-BD1 in complex with LT-872-297
分子名称: 1-[2-methyl-5-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-4-(1-methylpyrazol-4-yl)-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4
著者Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y.
登録日2021-03-31
公開日2022-04-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献RD4-BD1 in complex with LT-872-297
To Be Published
7D4O
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BU of 7d4o by Molmil
cyclic trinucleotide synthase CdnD in complex with ATP and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-AMP-GMP synthase, ...
著者Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y.
登録日2020-09-24
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
Nucleic Acids Res., 49, 2021
7D48
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BU of 7d48 by Molmil
apo-form cyclic trinucleotide synthase CdnD
分子名称: Cyclic AMP-AMP-GMP synthase, SODIUM ION
著者Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y.
登録日2020-09-23
公開日2021-03-17
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
Nucleic Acids Res., 49, 2021
7D4J
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BU of 7d4j by Molmil
ddATP complex of cyclic trinucleotide synthase CdnD
分子名称: 2',3'-dideoxyadenosine triphosphate, Cyclic AMP-AMP-GMP synthase, MAGNESIUM ION
著者Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y.
登録日2020-09-24
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
Nucleic Acids Res., 49, 2021
7D4U
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BU of 7d4u by Molmil
ATP complex with double mutant cyclic trinucleotide synthase CdnD
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-AMP-GMP synthase
著者Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y.
登録日2020-09-24
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
Nucleic Acids Res., 49, 2021
7D4S
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BU of 7d4s by Molmil
apo-form cyclic trinucleotide synthase CdnD
分子名称: Cyclic AMP-AMP-GMP synthase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION
著者Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y.
登録日2020-09-24
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
Nucleic Acids Res., 49, 2021
5U4J
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BU of 5u4j by Molmil
Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S12, ...
著者Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H.
登録日2016-12-04
公開日2017-01-11
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
7DV5
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BU of 7dv5 by Molmil
Human bile salt exporter ABCB11 in complex with taurocholate
分子名称: Bile salt export pump, TAUROCHOLIC ACID
著者Wang, L, How, W.T, Chen, Y.
登録日2021-01-12
公開日2022-01-19
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets.
Cell Res., 32, 2022
5U4I
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BU of 5u4i by Molmil
Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H.
登録日2016-12-04
公開日2017-01-11
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
5UJ4
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BU of 5uj4 by Molmil
Crystal structure of the KPC-2 beta-lactamase complexed with hydrolyzed faropenem
分子名称: (2R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-5-[(2R)-oxolan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylic acid, Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL
著者Pemberton, O.A, Chen, Y.
登録日2017-01-16
公開日2017-04-26
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular Basis of Substrate Recognition and Product Release by the Klebsiella pneumoniae Carbapenemase (KPC-2).
J. Med. Chem., 60, 2017
5UM6
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BU of 5um6 by Molmil
Crystal Structure of S. pombe Uba1 in a closed conformation
分子名称: 2-(decylamino)ethane-1-thiol, N-(2-{[(4-chlorophenyl)methyl]disulfanyl}ethyl)decan-1-amine, SULFATE ION, ...
著者Lv, Z, Yuan, L, Aldana-Masangkay, G, Atkison, J.H, Chen, Y, Olsen, S.K.
登録日2017-01-26
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.794 Å)
主引用文献Domain alternation and active site remodeling are conserved structural features of ubiquitin E1.
J. Biol. Chem., 292, 2017

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