5UM6

Crystal Structure of S. pombe Uba1 in a closed conformation

Summary for 5UM6

Entry DOI	10.2210/pdb5um6/pdb
Descriptor	Ubiquitin-activating enzyme E1 1, SULFATE ION, N-(2-{[(4-chlorophenyl)methyl]disulfanyl}ethyl)decan-1-amine, ... (4 entities in total)
Functional Keywords	rossmann-like fold, ubiquitin-like fold, ubiquitin activating enzyme, atp binding, ligase activity, atp/mg binding, ubiquitin e2 binding, ligase, transferase, ligase-ligase inhibitor complex, ligase/ligase inhibitor
Biological source	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Total number of polymer chains	1
Total formula weight	112332.43
Authors	Lv, Z.,Yuan, L.,Aldana-Masangkay, G.,Atkison, J.H.,Chen, Y.,Olsen, S.K. (deposition date: 2017-01-26, release date: 2017-06-14, Last modification date: 2023-10-04)
Primary citation	Lv, Z.,Yuan, L.,Atkison, J.H.,Aldana-Masangkay, G.,Chen, Y.,Olsen, S.K. Domain alternation and active site remodeling are conserved structural features of ubiquitin E1. J. Biol. Chem., 292:12089-12099, 2017 Cited by PubMed: 28572513 DOI: 10.1074/jbc.M117.787622 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.794 Å)

Structure validation