5CYI
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![BU of 5cyi by Molmil](/molmil-images/mine/5cyi) | CDK2/Cyclin A covalent complex with 6-(cyclohexylmethoxy)-N-(4-(vinylsulfonyl)phenyl)-9H-purin-2-amine (NU6300) | 分子名称: | 6-(cyclohexylmethoxy)-N-[4-(ethylsulfonyl)phenyl]-9H-purin-2-amine, Cyclin-A2, Cyclin-dependent kinase 2 | 著者 | Anscombe, E, Meschini, E, Vidal, R.M, Martin, M.P, Staunton, D, Geitmann, M, Danielson, U.H, Stanley, W.A, Wang, L.Z, Reuillon, T, Golding, B.T, Cano, C, Newell, D.R, Noble, M.E.M, Wedge, S.R, Endicott, J.A, Griffin, R.J. | 登録日 | 2015-07-30 | 公開日 | 2015-09-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification and Characterization of an Irreversible Inhibitor of CDK2. Chem.Biol., 22, 2015
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5D11
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![BU of 5d11 by Molmil](/molmil-images/mine/5d11) | Kinase domain of cSrc in complex with RL235 | 分子名称: | GLYCEROL, N-[3-({4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}oxy)phenyl]prop-2-enamide, Proto-oncogene tyrosine-protein kinase Src | 著者 | Becker, C, Gruetter, C, Engel, J, Rauh, D. | 登録日 | 2015-08-03 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach. J.Med.Chem., 58, 2015
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1JR6
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5D4O
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![BU of 5d4o by Molmil](/molmil-images/mine/5d4o) | Structure of CPII, a nitrogen regulatory PII-like protein from Thiomonas intermedia K12, bound to ADP, AMP and bicarbonate. | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, ... | 著者 | Wheatley, N.M, Ngo, J, Cascio, D, Sawaya, M.R, Yeates, T.O. | 登録日 | 2015-08-08 | 公開日 | 2016-09-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A PII-Like Protein Regulated by Bicarbonate: Structural and Biochemical Studies of the Carboxysome-Associated CPII Protein. J.Mol.Biol., 428, 2016
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1JTQ
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![BU of 1jtq by Molmil](/molmil-images/mine/1jtq) | E. coli TS Complex with dUMP and the Pyrrolo(2,3-d)pyrimidine-based Antifolate LY341770 | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-4-(2H-TETRAZOL-5-YL)-BUTYRIC ACID, THYMIDYLATE SYNTHASE | 著者 | Sayre, P.H, Finer-Moore, J.S, Fritz, T.A, Biermann, D, Gates, S.B, MacKellar, W.C, Patel, V.F, Stroud, R.M. | 登録日 | 2001-08-21 | 公開日 | 2001-09-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases. J.Mol.Biol., 313, 2001
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4JDD
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1JYI
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![BU of 1jyi by Molmil](/molmil-images/mine/1jyi) | CONCANAVALIN A/12-MER PEPTIDE COMPLEX | 分子名称: | 12-mer peptide, CALCIUM ION, Concanavalin-Br, ... | 著者 | Jain, D, Kaur, K.J, Sundaravadivel, B, Salunke, D.M. | 登録日 | 2001-09-12 | 公開日 | 2002-09-12 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural and Functional Consequences of Peptide-carbohydrate Mimicry. Crystal Structure of a Carbohydrate-mimicking Peptide Bound to Concanavalin A. J.Biol.Chem., 275, 2000
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1L5I
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![BU of 1l5i by Molmil](/molmil-images/mine/1l5i) | 30-CONFORMER NMR ENSEMBLE OF THE N-TERMINAL, DNA-BINDING DOMAIN OF THE REPLICATION INITIATION PROTEIN FROM A GEMINIVIRUS (TOMATO YELLOW LEAF CURL VIRUS-SARDINIA) | 分子名称: | Rep protein | 著者 | Campos-Olivas, R, Louis, J.M, Clerot, D, Gronenborn, B, Gronenborn, A.M. | 登録日 | 2002-03-07 | 公開日 | 2002-09-18 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of a replication initiator unites diverse aspects of nucleic acid metabolism Proc.Natl.Acad.Sci.USA, 99, 2002
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5DFN
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![BU of 5dfn by Molmil](/molmil-images/mine/5dfn) | Structure of Tetrahymena Telomerase P45 C-terminal domain | 分子名称: | Telomerase associated protein p45 | 著者 | Chan, H, Cascio, D, Sawaya, M.R, Feigon, J. | 登録日 | 2015-08-27 | 公開日 | 2015-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.382 Å) | 主引用文献 | Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science, 350, 2015
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5DB5
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![BU of 5db5 by Molmil](/molmil-images/mine/5db5) | Crystal structure of PLP-bound E. coli SufS (cysteine persulfide intermediate) in space group P21 | 分子名称: | 1,2-ETHANEDIOL, CITRIC ACID, CYSTEINE, ... | 著者 | Arbing, M.A, Shin, A, Koo, C.W, Medrano-Soto, A, Eisenberg, D. | 登録日 | 2015-08-20 | 公開日 | 2016-08-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal structure of PLP-bound E. coli SufS (cysteine persulfide intermediate) in space group P21 To Be Published
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1LOK
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![BU of 1lok by Molmil](/molmil-images/mine/1lok) | The 1.20 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica Complexed with Tris: A Tale of Buffer Inhibition | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bacterial leucyl aminopeptidase, SODIUM ION, ... | 著者 | Desmarais, W.T, Bienvenue, D.L, Bzymek, K.P, Holz, R.C, Petsko, G.A, Ringe, D. | 登録日 | 2002-05-06 | 公開日 | 2002-11-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | The 1.20 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica Complexed with Tris A tale of Buffer Inhibition Structure, 10, 2002
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4JJ3
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1LF5
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1KYN
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![BU of 1kyn by Molmil](/molmil-images/mine/1kyn) | Cathepsin-G | 分子名称: | (2-NAPHTHALEN-2-YL-1-NAPHTHALEN-1-YL-2-OXO-ETHYL)-PHOSPHONIC ACID, cathepsin G | 著者 | Greco, M.N, Hawkins, M.J, Powell, E.T, Almond Jr, H.R, Corcoran, T.W, De Garavilla, L, Kauffman, J.A, Recacha, R, Chattopadhyay, D, Andrade-Gordon, P, Maryanoff, B.E. | 登録日 | 2002-02-05 | 公開日 | 2002-05-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design. J.Am.Chem.Soc., 124, 2002
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5DH7
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![BU of 5dh7 by Molmil](/molmil-images/mine/5dh7) | Two divalent metal ions and conformational changes play roles in the hammerhead ribozyme cleavage reaction-G12A mutant in Mn2+ | 分子名称: | 5'-R(*GP*GP*GP*CP*GP*UP*DC*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', MANGANESE (II) ION, RNA (48-MER) | 著者 | Mir, A, Chen, J, Neau, D, Golden, B.L. | 登録日 | 2015-08-29 | 公開日 | 2015-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.064 Å) | 主引用文献 | Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction. Biochemistry, 54, 2015
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5CPT
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![BU of 5cpt by Molmil](/molmil-images/mine/5cpt) | Disproportionating enzyme 1 from Arabidopsis - beta cyclodextrin soak | 分子名称: | 1,2-ETHANEDIOL, 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic, ... | 著者 | O'Neill, E.C, Stevenson, C.E.M, Tantanarat, K, Latousakis, D, Donaldson, M.I, Rejzek, M, Limpaseni, T, Smith, A.M, Field, R.A, Lawson, D.M. | 登録日 | 2015-07-21 | 公開日 | 2015-11-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1). J.Biol.Chem., 290, 2015
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1L2M
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![BU of 1l2m by Molmil](/molmil-images/mine/1l2m) | Minimized Average Structure of the N-terminal, DNA-binding domain of the replication initiation protein from a geminivirus (Tomato yellow leaf curl virus-Sardinia) | 分子名称: | Rep protein | 著者 | Campos-Olivas, R, Louis, J.M, Clerot, D, Gronenborn, B, Gronenborn, A.M. | 登録日 | 2002-02-22 | 公開日 | 2002-09-18 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of a replication initiator unites diverse aspects of nucleic acid metabolism Proc.Natl.Acad.Sci.USA, 99, 2002
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1L0A
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![BU of 1l0a by Molmil](/molmil-images/mine/1l0a) | DOWNSTREAM REGULATOR TANK BINDS TO THE CD40 RECOGNITION SITE ON TRAF3 | 分子名称: | TNF receptor associated factor 3, TRAF family member-associated NF-kappa-b activator | 著者 | Li, C, Ni, C.-Z, Havert, M.L, Cabezas, E, He, J, Kaiser, D, Reed, J.C, Satterthwait, A.C, Cheng, G, Ely, K.R. | 登録日 | 2002-02-08 | 公開日 | 2002-04-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Downstream regulator TANK binds to the CD40 recognition site on TRAF3. Structure, 10, 2002
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1L7Y
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![BU of 1l7y by Molmil](/molmil-images/mine/1l7y) | Solution NMR Structure of C. elegans Protein ZK652.3. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET WR41. | 分子名称: | HYPOTHETICAL PROTEIN ZK652.3 | 著者 | Cort, J.R, Chiang, Y, Zheng, D, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2002-03-18 | 公開日 | 2002-08-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of conserved eukaryotic protein ZK652.3 from C. elegans: a ubiquitin-like fold. Proteins, 48, 2002
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5D4L
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![BU of 5d4l by Molmil](/molmil-images/mine/5d4l) | Structure of the apo form of CPII from Thiomonas intermedia K12, a nitrogen regulatory PII-like protein | 分子名称: | Nitrogen regulatory protein P-II | 著者 | Wheatley, N.M, Ngo, J, Cascio, D, Sawaya, M.R, Yeates, T.O. | 登録日 | 2015-08-08 | 公開日 | 2016-09-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A PII-Like Protein Regulated by Bicarbonate: Structural and Biochemical Studies of the Carboxysome-Associated CPII Protein. J.Mol.Biol., 428, 2016
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5D9D
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![BU of 5d9d by Molmil](/molmil-images/mine/5d9d) | Luciferin-regenerating enzyme solved by SAD using synchrotron radiation at room temperature | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Luciferin regenerating enzyme, MAGNESIUM ION, ... | 著者 | Yamashita, K, Pan, D, Okuda, T, Murai, T, Kodan, A, Yamaguchi, T, Gomi, K, Kajiyama, N, Kato, H, Ago, H, Yamamoto, M, Nakatsu, T. | 登録日 | 2015-08-18 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | 主引用文献 | An isomorphous replacement method for efficient de novo phasing for serial femtosecond crystallography. Sci Rep, 5, 2015
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5D6S
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![BU of 5d6s by Molmil](/molmil-images/mine/5d6s) | Structure of epoxyqueuosine reductase from Streptococcus thermophilus. | 分子名称: | COBALAMIN, Epoxyqueuosine reductase, IRON/SULFUR CLUSTER | 著者 | Payne, K.A.P, Fisher, K, Dunstan, M.S, Sjuts, H, Leys, D. | 登録日 | 2015-08-12 | 公開日 | 2015-09-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Epoxyqueuosine Reductase Structure Suggests a Mechanism for Cobalamin-dependent tRNA Modification. J.Biol.Chem., 290, 2015
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5D8I
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1HK9
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1HUR
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![BU of 1hur by Molmil](/molmil-images/mine/1hur) | HUMAN ADP-RIBOSYLATION FACTOR 1 COMPLEXED WITH GDP, FULL LENGTH NON-MYRISTOYLATED | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, HUMAN ADP-RIBOSYLATION FACTOR 1, MAGNESIUM ION | 著者 | Amor, J.C, Harrison, D.H, Kahn, R.A, Ringe, D. | 登録日 | 1995-04-19 | 公開日 | 1995-07-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the human ADP-ribosylation factor 1 complexed with GDP. Nature, 372, 1994
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