1KYN
Cathepsin-G
Summary for 1KYN
Entry DOI | 10.2210/pdb1kyn/pdb |
Descriptor | cathepsin G, (2-NAPHTHALEN-2-YL-1-NAPHTHALEN-1-YL-2-OXO-ETHYL)-PHOSPHONIC ACID (2 entities in total) |
Functional Keywords | serine protease, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cell surface: P08311 |
Total number of polymer chains | 2 |
Total formula weight | 54356.26 |
Authors | Greco, M.N.,Hawkins, M.J.,Powell, E.T.,Almond Jr., H.R.,Corcoran, T.W.,De Garavilla, L.,Kauffman, J.A.,Recacha, R.,Chattopadhyay, D.,Andrade-Gordon, P.,Maryanoff, B.E. (deposition date: 2002-02-05, release date: 2002-05-01, Last modification date: 2011-07-13) |
Primary citation | Greco, M.N.,Hawkins, M.J.,Powell, E.T.,Almond Jr., H.R.,Corcoran, T.W.,de Garavilla, L.,Kauffman, J.A.,Recacha, R.,Chattopadhyay, D.,Andrade-Gordon, P.,Maryanoff, B.E. Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design. J.Am.Chem.Soc., 124:3810-3811, 2002 Cited by PubMed: 11942800DOI: 10.1021/ja017506h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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