7Y78
 
 | | Crystal structure of Cry78Aa | | 分子名称: | 1,2-ETHANEDIOL, AMMONIUM ION, Toxin | | 著者 | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | | 登録日 | 2022-06-21 | | 公開日 | 2022-08-31 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity.
Commun Biol, 5, 2022
|
|
7Y79
 | | Crystal structure of Cry78Aa | | 分子名称: | Toxin | | 著者 | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | | 登録日 | 2022-06-21 | | 公開日 | 2022-08-31 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity.
Commun Biol, 5, 2022
|
|
7YIM
 | | Cryo-EM structure of human Alpha-fetoprotein | | 分子名称: | Alpha-fetoprotein | | 著者 | Liu, N, Liu, K, Wu, C, Liu, Z, Li, M, Wang, J, Wang, H.W. | | 登録日 | 2022-07-17 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM.
Nat.Methods, 20, 2023
|
|
7YGW
 | | Crystal structure of the Zn2+-bound EFhd1/Swiprosin-2 | | 分子名称: | EF-hand domain-containing protein D1, GLYCEROL, ZINC ION | | 著者 | Mun, S.A, Park, J, Kang, J.Y, Park, T, Jin, M, Yang, J, Eom, S.H. | | 登録日 | 2022-07-12 | | 公開日 | 2023-03-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2.
Iucrj, 10, 2023
|
|
7YGY
 | | Crystal structure of the Zn2+-bound EFhd2/Swiprosin-1 | | 分子名称: | EF-hand domain-containing protein D2, ZINC ION | | 著者 | Mun, S.A, Park, J, Kang, J.Y, Park, T, Jin, M, Yang, J, Eom, S.H. | | 登録日 | 2022-07-12 | | 公開日 | 2023-03-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2.
Iucrj, 10, 2023
|
|
6KY4
 | | Crystal structure of Sulfiredoxin from Arabidopsis thaliana | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, Sulfiredoxin, ... | | 著者 | Liu, M, Wang, J, Li, X, Li, M, Sylvanno, M.J, Zhang, M, Wang, M. | | 登録日 | 2019-09-16 | | 公開日 | 2019-10-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The crystal structure of sulfiredoxin from Arabidopsis thaliana revealed a more robust antioxidant mechanism in plants.
Biochem.Biophys.Res.Commun., 520, 2019
|
|
1MP5
 | | Y177F VARIANT OF S. ENTERICA RmlA | | 分子名称: | URIDINE-5'-DIPHOSPHATE-GLUCOSE, Y177F VARIANT OF S. ENTERICA RmlA BOUND TO UDP-GLUCOSE | | 著者 | Barton, W.A, Biggins, J.B, Jiang, J, Thorson, J.S, Nikolov, D.B. | | 登録日 | 2002-09-11 | | 公開日 | 2002-10-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
1MP4
 | | W224H VARIANT OF S. ENTERICA RmlA | | 分子名称: | URIDINE-5'-DIPHOSPHATE-GLUCOSE, W224H Variant of S. Enterica RmlA Bound to UDP-Glucose | | 著者 | Barton, W.A, Biggins, J.B, Jiang, J, Thorson, J.S, Nikolov, D.B. | | 登録日 | 2002-09-11 | | 公開日 | 2002-10-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
1MHK
 | | Crystal Structure Analysis of a 26mer RNA molecule, representing a new RNA motif, the hook-turn | | 分子名称: | BROMIDE ION, RNA 12-mer BCh12, RNA 14-mer BCh12 | | 著者 | Szep, S, Wang, J, Moore, P.B. | | 登録日 | 2002-08-20 | | 公開日 | 2002-09-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structure of a 26-nucleotide RNA containing a hook-turn
RNA, 9, 2003
|
|
1MP3
 | | L89T VARIANT OF S. ENTERICA RmlA | | 分子名称: | GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, THYMIDINE-5'-TRIPHOSPHATE | | 著者 | Barton, W.A, Biggins, J.B, Jiang, J, Thorson, J.T, Nikolov, D.B. | | 登録日 | 2002-09-11 | | 公開日 | 2002-10-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
1MIY
 | | Crystal structure of Bacillus stearothermophilus CCA-adding enzyme in complex with CTP | | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tRNA CCA-adding enzyme | | 著者 | Li, F, Xiong, Y, Wang, J, Cho, H.D, Weiner, A.M, Steitz, T.A. | | 登録日 | 2002-08-23 | | 公開日 | 2002-12-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | | 主引用文献 | Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and
its complexes with ATP or CTP
Cell(Cambridge,Mass.), 111, 2002
|
|
6DDT
 | | mouse beta-mannosidase (MANBA) | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gytz, H, Liang, J, Liang, Y, Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2018-05-10 | | 公開日 | 2019-01-09 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The structure of mammalian beta-mannosidase provides insight into beta-mannosidosis and nystagmus.
FEBS J., 286, 2019
|
|
8EHK
 | |
8EHM
 | |
8EHL
 | |
8EHJ
 | |
7YGF
 | | Crystal structure of YggS from Fusobacterium nucleatum | | 分子名称: | Pyridoxal phosphate homeostasis protein, SULFATE ION | | 著者 | He, S.R, Chan, Y.Y, Wang, L.L, Bai, X, Bu, T.T, Zhang, J, Xu, Y.B. | | 登録日 | 2022-07-11 | | 公開日 | 2022-10-12 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Structural and Functional Analysis of the Pyridoxal Phosphate Homeostasis Protein YggS from Fusobacterium nucleatum.
Molecules, 27, 2022
|
|
5CTY
 | | Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-[2-(pyridin-3-yl)-1,3-thiazol-5-yl]-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, CHLORIDE ION, ... | | 著者 | Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D. | | 登録日 | 2015-07-24 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Bioorg.Med.Chem.Lett., 26, 2016
|
|
6DU8
 | | Human Polycsytin 2-l1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystic kidney disease 2-like 1 protein | | 著者 | Hulse, R.E, Clapham, D.E, Li, Z, Huang, R.K, Zhang, J. | | 登録日 | 2018-06-20 | | 公開日 | 2018-07-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | Cryo-EM structure of the polycystin 2-l1 ion channel.
Elife, 7, 2018
|
|
8GOU
 | | Omicron BA.4/5 SARS-CoV-2 S in complex with TH003 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH003 Fab heavy chain, ... | | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | | 登録日 | 2022-08-25 | | 公開日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection.
Nat Commun, 14, 2023
|
|
6QLD
 | | Structure of inner kinetochore CCAN-Cenp-A complex | | 分子名称: | DNA (125-MER), Histone H2A.1, Histone H2B.1, ... | | 著者 | Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D. | | 登録日 | 2019-01-31 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.15 Å) | | 主引用文献 | Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
|
|
6QLF
 | | Structure of inner kinetochore CCAN complex with mask1 | | 分子名称: | Inner kinetochore subunit AME1, Inner kinetochore subunit CHL4, Inner kinetochore subunit CTF19, ... | | 著者 | Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D. | | 登録日 | 2019-01-31 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
|
|
4OI7
 | | RAGE recognizes nucleic acids and promotes inflammatory responses to DNA | | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*CP*AP*CP*GP*TP*TP*CP*GP*TP*AP*GP*CP*AP*TP*CP*GP*TP*TP*GP*CP*AP*G)-3', 5'-D(*CP*TP*GP*CP*AP*AP*CP*GP*AP*TP*GP*CP*TP*AP*CP*GP*AP*AP*CP*GP*TP*G)-3', ... | | 著者 | Jin, T, Jiang, J, Xiao, T. | | 登録日 | 2014-01-19 | | 公開日 | 2014-04-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.104 Å) | | 主引用文献 | RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
J.Exp.Med., 210, 2013
|
|
4FLH
 | | Crystal structure of human PI3K-gamma in complex with AMG511 | | 分子名称: | 4-(2-[(5-fluoro-6-methoxypyridin-3-yl)amino]-5-{(1R)-1-[4-(methylsulfonyl)piperazin-1-yl]ethyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | | 著者 | Whittington, D.A, Tang, J, Yakowec, P. | | 登録日 | 2012-06-14 | | 公開日 | 2012-08-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511.
J.Med.Chem., 55, 2012
|
|
4OCZ
 | | Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-isobutyrylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea | | 分子名称: | 1-[1-(2-methylpropanoyl)piperidin-4-yl]-3-[4-(trifluoromethyl)phenyl]urea, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... | | 著者 | Lee, K.S.S, Liu, J, Wagner, K.M, Pakhomova, S, Dong, H, Morriseau, C, Fu, S.H, Yang, J, Wang, P, Ulu, A, Mate, C, Nguyen, L, Wullf, H, Eldin, M.L, Mara, A.A, Newcomer, M.E, Zeldin, D.C, Hammock, B.D. | | 登録日 | 2014-01-09 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy.
J.Med.Chem., 57, 2014
|
|
