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5YHQ
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BU of 5yhq by Molmil
Cryo-EM Structure of CVA6 VLP
分子名称: Capsid protein VP1, Capsid protein VP3, capsid protein VP0
著者Chen, J, Zhang, C, Huang, Z, Cong, Y.
登録日2017-09-29
公開日2017-10-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A 3.0-Angstrom Resolution Cryo-Electron Microscopy Structure and Antigenic Sites of Coxsackievirus A6-Like Particles.
J. Virol., 92, 2018
5XS7
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BU of 5xs7 by Molmil
Structure of Coxsackievirus A6 (CVA6) virus A-particle in complex with the neutralizing antibody fragment 1D5
分子名称: Genome polyprotein, Heavy chain of Fab 1D5, Light chain of Fab 1D5
著者Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Li, S.W, Cheng, T.
登録日2017-06-12
公開日2017-09-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
Nat Commun, 8, 2017
7ZHF
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BU of 7zhf by Molmil
GPN-loop GTPase from Sulfolobus acidocaldarius closed state (GppNHp)
分子名称: CHLORIDE ION, GLYCEROL, GTPase, ...
著者Korf, L, Essen, L.-O.
登録日2022-04-06
公開日2023-10-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Archaeal GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis.
Mbio, 14, 2023
7ZHK
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BU of 7zhk by Molmil
GPN-loop GTPase from Sulfolobus acidocaldarius open state (GDP)
分子名称: GTPase, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Korf, L, Essen, L.-O.
登録日2022-04-06
公開日2023-10-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Archaeal GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis.
Mbio, 14, 2023
8QBJ
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BU of 8qbj by Molmil
Structure of mBaoJin at pH 4.6
分子名称: CHLORIDE ION, mBaoJin
著者Samygina, V.R, Vlaskina, A.V, Gabdulkhakov, A, Subach, O.M, Subach, F.V.
登録日2023-08-24
公開日2023-12-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bright and stable monomeric green fluorescent protein derived from StayGold.
Nat.Methods, 21, 2024
4O8S
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BU of 4o8s by Molmil
Crystal structure of JHP933 from Helicobacter pylori
分子名称: Putative
著者Zhao, Y.H, Su, Y.T, Sun, L.F, Wu, Y.
登録日2013-12-30
公開日2014-09-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure Confirmation of JHP933 as a Nucleotidyltransferase Superfamily Protein from Helicobacter pylori Strain J99
Plos One, 9, 2014
8QDD
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BU of 8qdd by Molmil
Structure of mBaoJin at pH 8.5
分子名称: CHLORIDE ION, SULFATE ION, mBaoJin
著者Samygina, V.R, Vlaskina, A.V, Gabdulkhakov, A, Subach, O.M, Subach, F.V.
登録日2023-08-28
公開日2023-12-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Bright and stable monomeric green fluorescent protein derived from StayGold.
Nat.Methods, 21, 2024
8Q79
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BU of 8q79 by Molmil
Structure of mBaoJin at pH 6.5
分子名称: CHLORIDE ION, mBaoJin
著者Samygina, V.R, Subach, O.M, Vlaskina, A.V, Nikolaeva, A.Y, Borshchevsky, V, Qin, W, Subach, F.V.
登録日2023-08-15
公開日2023-12-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Bright and stable monomeric green fluorescent protein derived from StayGold.
Nat.Methods, 21, 2024
7KBB
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BU of 7kbb by Molmil
Cryo-EM structure of the HCMV pentamer bound by Fabs 2-18 and 8I21
分子名称: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain, 8I21 Fab Heavy Chain, ...
著者Wrapp, D, McLellan, J.S.
登録日2020-10-01
公開日2021-08-11
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7KBA
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BU of 7kba by Molmil
Crystal structure of the HCMV pentamer-specific Fab 2-18
分子名称: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain
著者Wrapp, D, McLellan, J.S.
登録日2020-10-01
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
6LGN
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BU of 6lgn by Molmil
The atomic structure of varicella zoster virus C-capsid
分子名称: Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ...
著者Li, S, Zheng, Q.
登録日2019-12-05
公開日2020-07-29
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids.
Nat Microbiol, 5, 2020
6LGL
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BU of 6lgl by Molmil
The atomic structure of varicella-zoster virus A-capsid
分子名称: Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ...
著者Zheng, Q, Li, S.
登録日2019-12-05
公開日2020-07-29
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids.
Nat Microbiol, 5, 2020
8UN5
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BU of 8un5 by Molmil
KRAS-G13D-GDP in complex with Cpd38 ((E)-1-((3S)-4-(7-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-2-methylenetetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)-3-(1,2,3,4-tetrahydroisoquinolin-8-yl)prop-2-en-1-one)
分子名称: (2E)-1-{(3S)-4-[(7M)-7-[6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl]-6-chloro-8-fluoro-2-{[(4R,7aS)-2-methylidenetetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}quinazolin-4-yl]-3-methylpiperazin-1-yl}-3-(1,2,3,4-tetrahydroisoquinolin-8-yl)prop-2-en-1-one, GLYCEROL, GTPase KRas, ...
著者Ultsch, M.H.
登録日2023-10-18
公開日2023-12-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors.
Acs Med.Chem.Lett., 15, 2024
8UN3
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BU of 8un3 by Molmil
KRAS-G13D-GDP in complex with Cpd5 (1-((S)-10-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-11-chloro-7-(((2S,4R)-4-fluoro-1-methylpyrrolidin-2-yl)methoxy)-3,4,13,13a-tetrahydropyrazino[2',1':3,4][1,4]oxazepino[5,6,7-de]quinazolin-2(1H)-yl)prop-2-en-1-one)
分子名称: 1,2-ETHANEDIOL, 1-[(5M,8aS,13R)-5-[6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl]-6-chloro-2-{[(2S,4R)-4-fluoro-1-methylpyrrolidin-2-yl]methoxy}-8a,9,11,12-tetrahydropyrazino[2',1':3,4][1,4]oxazepino[5,6,7-de]quinazolin-10(8H)-yl]prop-2-en-1-one, CHLORIDE ION, ...
著者Ultsch, M.H.
登録日2023-10-18
公開日2023-12-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors.
Acs Med.Chem.Lett., 15, 2024
8UN4
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BU of 8un4 by Molmil
KRAS-G13D-GDP in complex with Cpd36 ((E)-1-((3S)-4-(7-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-2-methylenetetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)-3-(4-((dimethylamino)methyl)-5-methylpyridin-2-yl)prop-2-en-1-one)
分子名称: (2E)-1-{(3S)-4-[(7M)-7-[6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl]-6-chloro-8-fluoro-2-{[(4R,7aS)-2-methylidenetetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}quinazolin-4-yl]-3-methylpiperazin-1-yl}-3-{4-[(dimethylamino)methyl]-5-methylpyridin-2-yl}prop-2-en-1-one, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Ultsch, M.H.
登録日2023-10-18
公開日2023-12-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors.
Acs Med.Chem.Lett., 15, 2024
9B94
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BU of 9b94 by Molmil
Cryo-EM structure of the E396A mutant of human TRPM4 in complex with calcium at 37 degrees Celsius
分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B91
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BU of 9b91 by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and ATP at 37 degrees Celsius
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B90
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BU of 9b90 by Molmil
Cryo-EM structure of the human TRPM4 channel in complex with calcium and ATP at 37 degrees Celsius
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B93
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BU of 9b93 by Molmil
Cryo-EM structure of the human TRPM4 channel in the presence of EDTA at 37 degrees Celsius
分子名称: Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
7W6L
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BU of 7w6l by Molmil
The crystal structure of MLL3-RBBP5-ASH2L in complex with H3K4me0 peptide
分子名称: Histone H3.3C, Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, ...
著者Zhao, L, Li, Y, Chen, Y.
登録日2021-12-01
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
7W6A
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BU of 7w6a by Molmil
Crystal structure of the MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L complex
分子名称: Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Zhao, L, Li, Y, Chen, Y.
登録日2021-12-01
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
7W6I
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BU of 7w6i by Molmil
The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me1 peptide
分子名称: Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ...
著者Zhao, L, Li, Y, Chen, Y.
登録日2021-12-01
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
9B8Z
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BU of 9b8z by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and decavanadate at 37 degrees Celsius
分子名称: CALCIUM ION, DECAVANADATE, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B92
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BU of 9b92 by Molmil
Cryo-EM structure of the human TRPM4 in complex with calcium at 18 degrees Celsius
分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
7W67
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BU of 7w67 by Molmil
The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me0 peptide
分子名称: Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ...
著者Zhao, L, Li, Y, Chen, Y.
登録日2021-12-01
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.194 Å)
主引用文献Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022

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