5C9E
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![BU of 5c9e by Molmil](/molmil-images/mine/5c9e) | SepL | 分子名称: | BROMIDE ION, SepL | 著者 | Burkinshaw, B.J, Strynadka, N.C.J. | 登録日 | 2015-06-26 | 公開日 | 2015-10-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Structural analysis of SepL, an enteropathogenic Escherichia coli type III secretion system gatekeeper protein Acta Crystallogr.,Sect.F, 71, 2015
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5CXY
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![BU of 5cxy by Molmil](/molmil-images/mine/5cxy) | Structure of a Glycosyltransferase in Complex with Inhibitor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Volkers, G, Strynadka, N.C.J. | 登録日 | 2015-07-29 | 公開日 | 2016-09-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | To be published. To be published
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1Q16
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![BU of 1q16 by Molmil](/molmil-images/mine/1q16) | Crystal structure of Nitrate Reductase A, NarGHI, from Escherichia coli | 分子名称: | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, FE3-S4 CLUSTER, ... | 著者 | Bertero, M.G, Strynadka, N.C.J. | 登録日 | 2003-07-18 | 公開日 | 2003-10-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Insights into the respiratory electron transfer pathway from the structure of nitrate reductase A Nat.Struct.Biol., 10, 2003
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1K0W
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![BU of 1k0w by Molmil](/molmil-images/mine/1k0w) | CRYSTAL STRUCTURE OF L-RIBULOSE-5-PHOSPHATE 4-EPIMERASE | 分子名称: | L-RIBULOSE 5 PHOSPHATE 4-EPIMERASE, ZINC ION | 著者 | Luo, Y, Samuel, J, Mosimann, S.C, Lee, J.E, Strynadka, N.C.J. | 登録日 | 2001-09-21 | 公開日 | 2003-01-28 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The structure of L-ribulose-5-phosphate 4-epimerase: an aldolase-like platform for epimerization Biochemistry, 40, 2001
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5TW4
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![BU of 5tw4 by Molmil](/molmil-images/mine/5tw4) | |
5TY7
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![BU of 5ty7 by Molmil](/molmil-images/mine/5ty7) | Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with nafcillin | 分子名称: | (2R,4S)-2-[(1R)-1-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Penicillin-binding protein 4, SODIUM ION, ... | 著者 | Alexander, J.A.N, Strynadka, N.C.J. | 登録日 | 2016-11-18 | 公開日 | 2018-06-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.894 Å) | 主引用文献 | Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 2018
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5TX9
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![BU of 5tx9 by Molmil](/molmil-images/mine/5tx9) | Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftobiprole | 分子名称: | (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Penicillin-binding protein 4, SODIUM ION, ... | 著者 | Alexander, J.A.N, Strynadka, N.C.J. | 登録日 | 2016-11-16 | 公開日 | 2018-05-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 2018
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5TW8
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![BU of 5tw8 by Molmil](/molmil-images/mine/5tw8) | |
7KCX
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![BU of 7kcx by Molmil](/molmil-images/mine/7kcx) | Crystal structure of S. aureus penicillin-binding protein 4 (PBP4) mutant (R200L) in complex with cefoxitin | 分子名称: | (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, GLYCEROL, Penicillin-binding protein 4, ... | 著者 | Alexander, J.A.N, Strynadka, N.C.J. | 登録日 | 2020-10-07 | 公開日 | 2021-06-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | PBP4-mediated beta-lactam resistance among clinical strains of Staphylococcus aureus. J.Antimicrob.Chemother., 76, 2021
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7KCV
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![BU of 7kcv by Molmil](/molmil-images/mine/7kcv) | |
7KCY
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![BU of 7kcy by Molmil](/molmil-images/mine/7kcy) | Crystal structure of S. aureus penicillin-binding protein 4 (PBP4) with cefoxitin | 分子名称: | (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, GLYCEROL, Penicillin-binding protein 4, ... | 著者 | Alexander, J.A.N, Strynadka, N.C.J. | 登録日 | 2020-10-07 | 公開日 | 2021-06-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | PBP4-mediated beta-lactam resistance among clinical strains of Staphylococcus aureus. J.Antimicrob.Chemother., 76, 2021
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7JLR
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![BU of 7jlr by Molmil](/molmil-images/mine/7jlr) | |
7JLJ
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![BU of 7jlj by Molmil](/molmil-images/mine/7jlj) | |
7JLI
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![BU of 7jli by Molmil](/molmil-images/mine/7jli) | |
5TY2
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![BU of 5ty2 by Molmil](/molmil-images/mine/5ty2) | Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with nafcillin | 分子名称: | (2R,4S)-2-[(1R)-1-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, Penicillin-binding protein 4, ... | 著者 | Alexander, J.A.N, Strynadka, N.C.J. | 登録日 | 2016-11-18 | 公開日 | 2018-06-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 2018
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7KGM
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![BU of 7kgm by Molmil](/molmil-images/mine/7kgm) | C. rodentium YcbB - ertapenem complex | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Putative exported protein | 著者 | Caveney, N.A, Strynadka, N.C.J. | 登録日 | 2020-10-17 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and Cellular Insights into the l,d-Transpeptidase YcbB as a Therapeutic Target in Citrobacter rodentium, Salmonella Typhimurium, and Salmonella Typhi Infections. Antimicrob.Agents Chemother., 65, 2021
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7JP1
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![BU of 7jp1 by Molmil](/molmil-images/mine/7jp1) | |
7JOY
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![BU of 7joy by Molmil](/molmil-images/mine/7joy) | |
7K7K
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![BU of 7k7k by Molmil](/molmil-images/mine/7k7k) | |
7K08
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![BU of 7k08 by Molmil](/molmil-images/mine/7k08) | |
7JLM
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![BU of 7jlm by Molmil](/molmil-images/mine/7jlm) | |
7KGN
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![BU of 7kgn by Molmil](/molmil-images/mine/7kgn) | S. Typhi YcbB - ertapenem complex | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, L,D-transpeptidase | 著者 | Caveney, N.A, Strynadka, N.C.J. | 登録日 | 2020-10-18 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structural and Cellular Insights into the l,d-Transpeptidase YcbB as a Therapeutic Target in Citrobacter rodentium, Salmonella Typhimurium, and Salmonella Typhi Infections. Antimicrob.Agents Chemother., 65, 2021
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7KHP
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![BU of 7khp by Molmil](/molmil-images/mine/7khp) | Acyl-enzyme intermediate structure of SARS-CoV-2 Mpro in complex with its C-terminal autoprocessing sequence. | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE | 著者 | Lee, J, Worrall, L.J, Paetzel, M, Strynadka, N.C.J. | 登録日 | 2020-10-21 | 公開日 | 2020-10-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site. Nat Commun, 11, 2020
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5TXI
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![BU of 5txi by Molmil](/molmil-images/mine/5txi) | Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftobiprole | 分子名称: | (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ... | 著者 | Alexander, J.A.N, Strynadka, N.C.J. | 登録日 | 2016-11-16 | 公開日 | 2018-05-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 2018
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6XBF
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![BU of 6xbf by Molmil](/molmil-images/mine/6xbf) | Structure of NDM-1 in complex with macrocycle inhibitor NDM1i-1G | 分子名称: | BlaNDM-4_1_JQ348841, ZINC ION, macrocycle inhibitor NDM1i-1G | 著者 | Worrall, L.J, Sun, T, Mulligan, V.K, Strynadka, N.C.J. | 登録日 | 2020-06-05 | 公開日 | 2021-03-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Computationally designed peptide macrocycle inhibitors of New Delhi metallo-beta-lactamase 1. Proc.Natl.Acad.Sci.USA, 118, 2021
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