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5CXY

Structure of a Glycosyltransferase in Complex with Inhibitor

Summary for 5CXY
Entry DOI10.2210/pdb5cxy/pdb
Related5BO6
DescriptorSia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywordssialyltransferase, inhibitor, polysialyltransferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (Human)
Cellular locationGolgi apparatus membrane ; Single-pass type II membrane protein : O43173
Total number of polymer chains2
Total formula weight80235.83
Authors
Volkers, G.,Strynadka, N.C.J. (deposition date: 2015-07-29, release date: 2016-09-07, Last modification date: 2023-09-27)
Primary citationVolkers, G.,Strynadka, N.C.J.
To be published.
To be published,
Experimental method
X-RAY DIFFRACTION (2.15 Å)
Structure validation

217705

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