7JLM
Crystal structure of Bacillus subtilis UppS in complex with MAC-0547630
Summary for 7JLM
Entry DOI | 10.2210/pdb7jlm/pdb |
Related | 7JLI |
Descriptor | Isoprenyl transferase, CITRIC ACID, 7-(azepan-1-yl)-3-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidine, ... (4 entities in total) |
Functional Keywords | undecaprenyl, cis-prenyltransferase, carrier lipid, mac-0547630, transferase |
Biological source | Bacillus subtilis |
Total number of polymer chains | 2 |
Total formula weight | 60661.27 |
Authors | Workman, S.D.,Strynadka, N.C.J. (deposition date: 2020-07-29, release date: 2021-08-04, Last modification date: 2023-10-18) |
Primary citation | Workman, S.D.,Day, J.,Farha, M.A.,El Zahed, S.S.,Bon, C.,Brown, E.D.,Organ, M.G.,Strynadka, N.C.J. Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria. J.Med.Chem., 64:13540-13550, 2021 Cited by PubMed: 34473495DOI: 10.1021/acs.jmedchem.1c00941 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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