7JLM
Crystal structure of Bacillus subtilis UppS in complex with MAC-0547630
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004659 | molecular_function | prenyltransferase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0008834 | molecular_function | di-trans,poly-cis-undecaprenyl-diphosphate synthase activity |
| A | 0016094 | biological_process | polyprenol biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0045547 | molecular_function | dehydrodolichyl diphosphate synthase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004659 | molecular_function | prenyltransferase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0008834 | molecular_function | di-trans,poly-cis-undecaprenyl-diphosphate synthase activity |
| B | 0016094 | biological_process | polyprenol biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0045547 | molecular_function | dehydrodolichyl diphosphate synthase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CIT A 301 |
| Chain | Residue |
| A | ASN88 |
| A | LYS90 |
| A | ARG208 |
| A | ARG214 |
| A | SER216 |
| A | HOH435 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue V07 A 302 |
| Chain | Residue |
| A | GLY60 |
| A | MET61 |
| A | ALA83 |
| A | LEU99 |
| A | LEU102 |
| A | PRO103 |
| A | PHE106 |
| A | ILE123 |
| A | ILE138 |
| A | PHE155 |
| A | LEU157 |
| A | MET39 |
| A | ASN42 |
| A | HIS57 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue CIT B 301 |
| Chain | Residue |
| B | MET39 |
| B | ASP40 |
| B | GLY41 |
| B | ASN42 |
| B | GLY43 |
| B | ARG44 |
| B | HIS57 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | binding site for residue V07 B 302 |
| Chain | Residue |
| B | MET39 |
| B | ASN42 |
| B | HIS57 |
| B | MET61 |
| B | VAL64 |
| B | LEU99 |
| B | MET100 |
| B | LEU102 |
| B | PRO103 |
| B | PHE106 |
| B | LEU107 |
| B | ILE138 |
| B | PHE155 |
| B | LEU157 |
Functional Information from PROSITE/UniProt
| site_id | PS01066 |
| Number of Residues | 18 |
| Details | UPP_SYNTHASE Undecaprenyl pyrophosphate synthase family signature. ELLIRTSGeiRlSnFMLW |
| Chain | Residue | Details |
| A | GLU204-TRP221 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_01139 |
| Chain | Residue | Details |
| A | ASP40 | |
| B | ASP40 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_01139 |
| Chain | Residue | Details |
| A | ASN88 | |
| B | ASN88 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 22 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01139 |
| Chain | Residue | Details |
| A | ASP40 | |
| A | ARG214 | |
| A | GLU227 | |
| B | ASP40 | |
| B | GLY41 | |
| B | TRP45 | |
| B | ARG53 | |
| B | HIS57 | |
| B | SER85 | |
| B | TRP89 | |
| B | ARG91 | |
| A | GLY41 | |
| B | ARG208 | |
| B | ARG214 | |
| B | GLU227 | |
| A | TRP45 | |
| A | ARG53 | |
| A | HIS57 | |
| A | SER85 | |
| A | TRP89 | |
| A | ARG91 | |
| A | ARG208 |
