7JLM
Crystal structure of Bacillus subtilis UppS in complex with MAC-0547630
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0004659 | molecular_function | prenyltransferase activity |
A | 0005829 | cellular_component | cytosol |
A | 0008834 | molecular_function | di-trans,poly-cis-undecaprenyl-diphosphate synthase activity |
A | 0016094 | biological_process | polyprenol biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
A | 0030145 | molecular_function | manganese ion binding |
A | 0045547 | molecular_function | dehydrodolichyl diphosphate synthase activity |
A | 0046872 | molecular_function | metal ion binding |
B | 0000287 | molecular_function | magnesium ion binding |
B | 0004659 | molecular_function | prenyltransferase activity |
B | 0005829 | cellular_component | cytosol |
B | 0008834 | molecular_function | di-trans,poly-cis-undecaprenyl-diphosphate synthase activity |
B | 0016094 | biological_process | polyprenol biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
B | 0030145 | molecular_function | manganese ion binding |
B | 0045547 | molecular_function | dehydrodolichyl diphosphate synthase activity |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue CIT A 301 |
Chain | Residue |
A | ASN88 |
A | LYS90 |
A | ARG208 |
A | ARG214 |
A | SER216 |
A | HOH435 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue V07 A 302 |
Chain | Residue |
A | GLY60 |
A | MET61 |
A | ALA83 |
A | LEU99 |
A | LEU102 |
A | PRO103 |
A | PHE106 |
A | ILE123 |
A | ILE138 |
A | PHE155 |
A | LEU157 |
A | MET39 |
A | ASN42 |
A | HIS57 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue CIT B 301 |
Chain | Residue |
B | MET39 |
B | ASP40 |
B | GLY41 |
B | ASN42 |
B | GLY43 |
B | ARG44 |
B | HIS57 |
site_id | AC4 |
Number of Residues | 14 |
Details | binding site for residue V07 B 302 |
Chain | Residue |
B | MET39 |
B | ASN42 |
B | HIS57 |
B | MET61 |
B | VAL64 |
B | LEU99 |
B | MET100 |
B | LEU102 |
B | PRO103 |
B | PHE106 |
B | LEU107 |
B | ILE138 |
B | PHE155 |
B | LEU157 |
Functional Information from PROSITE/UniProt
site_id | PS01066 |
Number of Residues | 18 |
Details | UPP_SYNTHASE Undecaprenyl pyrophosphate synthase family signature. ELLIRTSGeiRlSnFMLW |
Chain | Residue | Details |
A | GLU204-TRP221 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_01139 |
Chain | Residue | Details |
A | ASP40 | |
B | ASP40 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_01139 |
Chain | Residue | Details |
A | ASN88 | |
B | ASN88 |
site_id | SWS_FT_FI3 |
Number of Residues | 22 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01139 |
Chain | Residue | Details |
A | ASP40 | |
A | ARG214 | |
A | GLU227 | |
B | ASP40 | |
B | GLY41 | |
B | TRP45 | |
B | ARG53 | |
B | HIS57 | |
B | SER85 | |
B | TRP89 | |
B | ARG91 | |
A | GLY41 | |
B | ARG208 | |
B | ARG214 | |
B | GLU227 | |
A | TRP45 | |
A | ARG53 | |
A | HIS57 | |
A | SER85 | |
A | TRP89 | |
A | ARG91 | |
A | ARG208 |