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7P6A
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Limbic-predominant neuronal inclusion body 4R tauopathy type 1a tau filament
分子名称: Microtubule-associated protein tau
著者Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
登録日2021-07-15
公開日2021-09-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (1.9 Å)
主引用文献Structure-based classification of tauopathies.
Nature, 598, 2021
8OT9
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CTE typeIII tau filament from Guam ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTD
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TMEM106B Fold1-s filament from Guam ALS/PDC
分子名称: Transmembrane protein 106B
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTG
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BU of 8otg by Molmil
CTE typeI tau filament from Kii ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTH
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BU of 8oth by Molmil
TypeII tau filament from Kii ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTF
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Ab typeII filament from Guam ALS/PDC
分子名称: Amyloid-beta precursor protein
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTC
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BU of 8otc by Molmil
CTE typeII tau filament from Guam ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTJ
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BU of 8otj by Molmil
PHF tau filament from Kii ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OT6
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BU of 8ot6 by Molmil
CTE typeI tau filament from Guam ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTE
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BU of 8ote by Molmil
TMEM106B Fold I-d filament from Guam ALS/PDC
分子名称: Transmembrane protein 106B
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTI
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BU of 8oti by Molmil
CTE typeIII tau filament
分子名称: Microtubule-associated protein tau
著者Tetter, S, Qi, C, Ryskeldi-Falcon, B, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8PPO
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BU of 8ppo by Molmil
First Intermediate Amyloid (FIA) - Tau
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W, Goedert, M, Li, D.
登録日2023-07-07
公開日2023-08-02
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q2J
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BU of 8q2j by Molmil
Tau - AD-MIA2
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-02
公開日2023-08-30
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (2.23 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q27
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BU of 8q27 by Molmil
Tau: AD-MIA1
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W, Goedert, M, Li, D.
登録日2023-08-01
公開日2023-08-30
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (2.02 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q2K
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BU of 8q2k by Molmil
Tau - AD-MIA3
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-02
公開日2023-08-30
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q2L
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BU of 8q2l by Molmil
Tau - AD-MIA4
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-02
公開日2023-09-20
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8ORF
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BU of 8orf by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from corticobasal degeneration extracts
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-13
公開日2023-04-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
8ORE
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BU of 8ore by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from Alzheimer's Disease
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-13
公開日2023-04-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
8ORG
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BU of 8org by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from corticobasal degeneration extracts (Type II)
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-13
公開日2023-04-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
8P34
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BU of 8p34 by Molmil
Tau filaments extracted from human brain with the DeltaK281 mutation in MAPT
分子名称: Microtubule-associated protein tau
著者Schweighauser, M, Garringer, H.J, Klingstedt, T, Masuda-Suzukake, M, Murrell, J.R, Vidal, R, Scheres, S.H.W, Goedert, M, Ghetti, B, Newell, K.L.
登録日2023-05-17
公開日2023-07-05
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Mutation ∆K281 in MAPT causes Pick's disease.
Acta Neuropathol, 146, 2023
8Q7M
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BU of 8q7m by Molmil
Tau - AD-MIA7 (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-16
公開日2023-08-30
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q8D
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BU of 8q8d by Molmil
Tau - AD-LIA6 (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-18
公開日2023-08-30
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q8C
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BU of 8q8c by Molmil
Tau - AD-MIA10 (intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-18
公開日2023-09-06
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (1.92 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q7F
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BU of 8q7f by Molmil
Tau - AD-MIA5
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-16
公開日2023-08-30
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q9F
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BU of 8q9f by Molmil
Tau - CTE-LIA3 (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-20
公開日2023-09-06
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (1.91 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024

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件を2024-10-30に公開中

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