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4MAT
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E.COLI METHIONINE AMINOPEPTIDASE HIS79ALA MUTANT
分子名称: PROTEIN (METHIONINE AMINOPEPTIDASE), SODIUM ION
著者Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W.
登録日1999-03-29
公開日1999-06-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis.
Biochemistry, 38, 1999
2MAT
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BU of 2mat by Molmil
E.COLI METHIONINE AMINOPEPTIDASE AT 1.9 ANGSTROM RESOLUTION
分子名称: COBALT (II) ION, PROTEIN (METHIONINE AMINOPEPTIDASE), SODIUM ION
著者Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W.
登録日1999-03-29
公開日1999-06-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis.
Biochemistry, 38, 1999
7ROV
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BU of 7rov by Molmil
KRAS G12D Mutant in complex with GMPPCP and cyclic peptide MP-9903
分子名称: Cyclic peptide MP-9903, GLYCEROL, Isoform 2B of GTPase KRas, ...
著者Orth, P.
登録日2021-08-02
公開日2021-09-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling.
Chem Sci, 12, 2021
6JPV
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Structural analysis of AIMP2-DX2 and HSP70 interaction
分子名称: Heat shock 70 kDa protein 1A,Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
著者Cho, H.Y, Son, S.Y, Jeon, Y.H.
登録日2019-03-28
公開日2019-10-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.15000653 Å)
主引用文献Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.
Nat.Chem.Biol., 16, 2020
6K39
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Structural analysis of AIMP2-DX2 and HSP70 interaction
分子名称: Heat shock 70 kDa protein 1A,Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
著者Cho, H.Y, Son, S.Y, Jeon, Y.H.
登録日2019-05-16
公開日2019-10-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.3981427 Å)
主引用文献Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.
Nat.Chem.Biol., 16, 2020
8W1L
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BU of 8w1l by Molmil
Structure of CSF1R kinase domain in complex with Cpd 32
分子名称: GLYCEROL, Macrophage colony-stimulating factor 1 receptor,CSF1R, SULFATE ION, ...
著者Kothe, M, Chodaparambil, J.
登録日2024-02-16
公開日2024-05-29
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Identification of Selective Imidazopyridine CSF1R Inhibitors.
Acs Med.Chem.Lett., 15, 2024
3KX9
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BU of 3kx9 by Molmil
Engineering a closed form of the Archaeoglobus fulgidus ferritin by site directed mutagenesis
分子名称: Ferritin, GLYCEROL
著者Johnson, E, Cascio, D, Sawaya, M.R.
登録日2009-12-02
公開日2010-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献The role of nonconserved residues of Archaeoglobus fulgidus ferritin on its unique structure and biophysical properties.
J.Biol.Chem., 288, 2013
8F6O
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anti-BTLA monoclonal antibody h22B3 in complex with BTLA
分子名称: B- and T-lymphocyte attenuator, h22B3 Fab heavy chain, h22B3 Fab light chain
著者Hendle, J, Atwell, S, Lieu, R, Hickey, M, Weichert, K.
登録日2022-11-16
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA.
Structure, 31, 2023
8F60
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anti-BTLA monoclonal antibody r23C8 in complex with BTLA
分子名称: ACETATE ION, B- and T-lymphocyte attenuator, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hendle, J, Atwell, S, Lieu, R, Hickey, M, Weichert, K.
登録日2022-11-15
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA.
Structure, 31, 2023
8F6L
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anti-BTLA monoclonal antibody h25F7 in complex with BTLA
分子名称: B- and T-lymphocyte attenuator, h25F7 Fab heavy chain, h25F7 Fab light chain
著者Hendle, J, Atwell, S, Lieu, R, Hickey, M, Weichert, K.
登録日2022-11-16
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA.
Structure, 31, 2023
3NB9
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Crystal structure of radical H88Q Synechocystis sp. PCYA
分子名称: 1,2-ETHANEDIOL, BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase
著者Gae, D.D.
登録日2010-06-03
公開日2010-10-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for hydration dynamics in radical stabilization of bilin reductase mutants.
Biochemistry, 49, 2010
3NB8
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Crystal structure of oxidized H88Q Synechocystis sp. PCYA
分子名称: 1,2-ETHANEDIOL, BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase
著者Gae, D.D.
登録日2010-06-03
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural basis for hydration dynamics in radical stabilization of bilin reductase mutants.
Biochemistry, 49, 2010
6AAW
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BU of 6aaw by Molmil
Mdm2 in complex with a D amino Acid Containing Stapled Peptide
分子名称: ACE-LEU-THR-PHE-STQ-GLU-TYR-DTR-GLN-LEU-CBA-MK8-SER-ALA-ALA, E3 ubiquitin-protein ligase Mdm2
著者Brown, C.J, Partridge, A.W.
登録日2018-07-19
公開日2019-07-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Model System to Explore Macrocyclic Peptide Structural and Chirality Relationships: Tolerance of helix-breaking residues within the context of a stapled peptide.
To Be Published
3F0M
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BU of 3f0m by Molmil
Crystal structure of radical D105N Synechocystis sp. PcyA
分子名称: 1,2-ETHANEDIOL, BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase
著者Kohler, A.C, Gae, D.D.
登録日2008-10-25
公開日2009-10-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for hydration dynamics in radical stabilization of bilin reductase mutants.
Biochemistry, 49, 2010
3F0L
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BU of 3f0l by Molmil
Crystal structure of oxidized D105N Synechocystis sp. PcyA
分子名称: 1,2-ETHANEDIOL, BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase
著者Kohler, A.C, Gae, D.D.
登録日2008-10-25
公開日2009-10-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural basis for hydration dynamics in radical stabilization of bilin reductase mutants.
Biochemistry, 49, 2010
7VWX
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BU of 7vwx by Molmil
CryoEM structure of football-shaped GroEL:ES2 with RuBisCO
分子名称: Chaperonin GroEL, Co-chaperonin GroES, Ribulose bisphosphate carboxylase
著者Kim, H, Roh, S.H.
登録日2021-11-12
公開日2022-01-12
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Cryo-EM structures of GroEL:ES 2 with RuBisCO visualize molecular contacts of encapsulated substrates in a double-cage chaperonin.
Iscience, 25, 2022
7E65
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The crystal structure of peptidoglycan peptidase in complex with inhibitor 3
分子名称: (2S)-2-acetamido-N-[(2R)-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]-3-(4-sulfamoylphenyl)propanamide, Peptidase M23, ZINC ION
著者Choi, Y, Min, K.J, Yoon, H.J, Lee, H.H.
登録日2021-02-21
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
7E60
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The crystal structure of peptidoglycan peptidase in complex with inhibitor 1
分子名称: (2~{R},6~{S})-2,6-diacetamido-7-[[(2~{R})-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]amino]-7-oxidanylidene-heptanoic acid, Peptidase M23, ZINC ION
著者Min, K, Yoon, H.J, Choi, Y, Lee, H.H.
登録日2021-02-21
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
7E69
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The crystal structure of peptidoglycan peptidase in complex with inhibitor 3-3
分子名称: N-oxidanyl-4-[(4-sulfamoylphenyl)methyl]benzamide, Peptidase M23, ZINC ION
著者Choi, Y, Min, K.J, Yoon, H.J, Lee, H.H.
登録日2021-02-21
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
7E61
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The crystal structure of peptidoglycan peptidase in complex with inhibitor 2
分子名称: 2-[[(3S)-3-acetamido-4-[[(2R)-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]amino]-4-oxidanylidene-butyl]-(phenylmethyl)amino]ethanoic acid, Peptidase M23, ZINC ION
著者Min, K.J, Yoon, H.J, Choi, Y, Lee, H.H.
登録日2021-02-21
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
7E64
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The crystal structure of peptidoglycan peptidase in complex with inhibitor 2-2
分子名称: 2-[[(3S)-3-acetamido-4-[[(2R)-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]amino]-4-oxidanylidene-butyl]amino]ethanoic acid, Peptidase M23, ZINC ION
著者Choi, Y, Min, K.J, Yoon, H.J, Lee, H.H.
登録日2021-02-21
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
7E67
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The crystal structure of peptidoglycan peptidase in complex with inhibitor 3-2
分子名称: N-oxidanyl-2-[4-(4-sulfamoylphenyl)phenyl]ethanamide, Peptidase M23, ZINC ION
著者Choi, Y, Min, K.J, Yoon, H.J, Lee, H.H.
登録日2021-02-21
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
7E66
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The crystal structure of peptidoglycan peptidase in complex with inhibitor 3-1
分子名称: N-[2-(oxidanylamino)-2-oxidanylidene-ethyl]-2-(4-sulfamoylphenyl)ethanamide, Peptidase M23, ZINC ION
著者Choi, Y, Min, K.J, Yoon, H.J, Lee, H.H.
登録日2021-02-21
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
7E63
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The crystal structure of peptidoglycan peptidase in complex with inhibitor 2-1
分子名称: 2-[[(3S)-3-acetamido-4-[[(2R)-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]amino]-4-oxidanylidene-butyl]-(cyclopentylmethyl)amino]ethanoic acid, Peptidase M23, ZINC ION
著者Choi, Y, Min, K.J, Yoon, H.J, Lee, H.H.
登録日2021-02-21
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
8RQU
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Structure of TEM1 beta-lactamase variant 70.a
分子名称: Beta-lactamase TEM-1, MAGNESIUM ION
著者Napie, E, Fram, B.F, Gauthier, N.P, Sander, C, Khan, A.R.
登録日2024-01-19
公開日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Simultaneous enhancement of multiple functional properties using evolution-informed protein design.
Biorxiv, 2023

221051

件を2024-06-12に公開中

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