8F60

anti-BTLA monoclonal antibody r23C8 in complex with BTLA

Summary for 8F60

Entry DOI	10.2210/pdb8f60/pdb
Descriptor	r23C8 Fab heavy chain, r23C8 Fab light chain, B- and T-lymphocyte attenuator, ... (6 entities in total)
Functional Keywords	monoclonal antibody, immune system
Biological source	Oryctolagus cuniculus More
Total number of polymer chains	3
Total formula weight	61664.45
Authors	Hendle, J.,Atwell, S.,Lieu, R.,Hickey, M.,Weichert, K. (deposition date: 2022-11-15, release date: 2023-05-24, Last modification date: 2023-10-25)
Primary citation	Cheung, T.C.,Atwell, S.,Bafetti, L.,Cuenca, P.D.,Froning, K.,Hendle, J.,Hickey, M.,Ho, C.,Huang, J.,Lieu, R.,Lim, S.,Lippner, D.,Obungu, V.,Ward-Kavanagh, L.,Weichert, K.,Ware, C.F.,Vendel, A.C. Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA. Structure, 31:958-, 2023 Cited by PubMed: 37279757 DOI: 10.1016/j.str.2023.05.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.64 Å)

Structure validation