8F60
anti-BTLA monoclonal antibody r23C8 in complex with BTLA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | r23C8 Fab heavy chain | polymer | 221 | 23285.1 | 1 | Oryctolagus cuniculus | ||
2 | B | r23C8 Fab light chain | polymer | 218 | 23035.4 | 1 | Oryctolagus cuniculus | ||
3 | C | B- and T-lymphocyte attenuator | polymer | 126 | 14536.3 | 1 | UniProt (Q7Z6A9) In PDB | Homo sapiens (human) | B- and T-lymphocyte-associated protein |
4 | K | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
5 | B | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
6 | water | water | 18.0 | 476 | Chemie (HOH) |
Sequence modifications
C: 31 - 150 (UniProt: Q7Z6A9)
PDB | External Database | Details |
---|---|---|
His 47 | Ser 47 | engineered mutation |
Glu 151 | - | expression tag |
Phe 152 | - | expression tag |
Ile 153 | - | expression tag |
Asp 154 | - | expression tag |
Gly 155 | - | expression tag |
Arg 156 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 60856.7 | |
Branched | Number of molecules | 1 |
Total formula weight | 748.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 59.0 | |
All* | Total formula weight | 61664.5 |