8F60
anti-BTLA monoclonal antibody r23C8 in complex with BTLA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | r23C8 Fab heavy chain | polymer | 221 | 23285.1 | 1 | Oryctolagus cuniculus | ||
| 2 | B (B) | r23C8 Fab light chain | polymer | 218 | 23035.4 | 1 | Oryctolagus cuniculus | ||
| 3 | C (C) | B- and T-lymphocyte attenuator | polymer | 126 | 14536.3 | 1 | UniProt (Q7Z6A9) | Homo sapiens (human) | B- and T-lymphocyte-associated protein |
| 4 | D (K) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 5 | E (B) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | F, G, H (A, B, C) | water | water | 18.0 | 476 | Chemie (HOH) |
Sequence modifications
C: 31 - 150 (UniProt: Q7Z6A9)
| PDB | External Database | Details |
|---|---|---|
| His 47 | Ser 47 | engineered mutation |
| Glu 151 | - | expression tag |
| Phe 152 | - | expression tag |
| Ile 153 | - | expression tag |
| Asp 154 | - | expression tag |
| Gly 155 | - | expression tag |
| Arg 156 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 60856.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 748.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 59.0 | |
| All* | Total formula weight | 61664.5 |
