7E63

The crystal structure of peptidoglycan peptidase in complex with inhibitor 2-1

Summary for 7E63

• Entry DOI: 10.2210/pdb7e63/pdb
• Related: 7E60 7E61
• Descriptor: Peptidase M23, ZINC ION, 2-[[(3S)-3-acetamido-4-[[(2R)-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]amino]-4-oxidanylidene-butyl]-(cyclopentylmethyl)amino]ethanoic acid, ... (4 entities in total)
• Functional Keywords: hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Campylobacter jejuni
• Total number of polymer chains: 2
• Total formula weight: 57444.76

Authors

Choi, Y.,Min, K.J.,Yoon, H.J.,Lee, H.H. (deposition date: 2021-02-21, release date: 2022-02-23, Last modification date: 2023-11-29)

• Primary citation: Choi, Y.,Park, J.S.,Kim, J.,Min, K.,Mahasenan, K.,Kim, C.,Yoon, H.J.,Lim, S.,Cheon, D.H.,Lee, Y.,Ryu, S.,Mobashery, S.,Kim, B.M.,Lee, H.H.; Structure-based inhibitor design for reshaping bacterial morphology; Commun Biol, 5:395-, 2022; DOI: 10.1038/s42003-022-03355-3

Experimental method

X-RAY DIFFRACTION (2.4 Å)