8AYY
| Poliovirus type 3 (strain Saukett) stabilised virus-like particle (PV3 SC8) in complex with GSH and Pleconaril | 分子名称: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, Capsid protein, VP0, ... | 著者 | Bahar, M.W, Fry, E.E, Stuart, D.I. | 登録日 | 2022-09-04 | 公開日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation. Commun Biol, 5, 2022
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8AYX
| Poliovirus type 3 (strain Saukett) stabilised virus-like particle (PV3 SC8) in complex with GSH and GPP3 | 分子名称: | 1-[(3S)-5-[4-[(E)-ETHOXYIMINOMETHYL]PHENOXY]-3-METHYL-PENTYL]-3-PYRIDIN-4-YL-IMIDAZOLIDIN-2-ONE, Capsid protein, VP0, ... | 著者 | Bahar, M.W, Fry, E.E, Stuart, D.I. | 登録日 | 2022-09-04 | 公開日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation. Commun Biol, 5, 2022
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8AYZ
| Poliovirus type 2 (strain MEF-1) virus-like particle in complex with capsid binder compound 17 | 分子名称: | 4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid, Capsid protein, VP0, ... | 著者 | Bahar, M.W, Fry, E.E, Stuart, D.I. | 登録日 | 2022-09-04 | 公開日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (1.88 Å) | 主引用文献 | A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation. Commun Biol, 5, 2022
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8CII
| Delta-RBD complex with BA.2-07 fab, SARS1-34 fab and C1 nanobody | 分子名称: | BA.2-07 fab Heavy Chain, BA.2-07 fab Light Chain, C1 nanobody, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I, Fry, E.E. | 登録日 | 2023-02-09 | 公開日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Potent cross-reactive mAbs from BA.4/5 breakthrough infection To Be Published
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8CIN
| BA.4/5-5 FAB IN COMPLEX WITH SARS-COV-2 BA.4 SPIKE GLYCOPROTEIN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA.4/5-5 fab HEAVY CHAIN, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I, Fry, E.E. | 登録日 | 2023-02-10 | 公開日 | 2024-02-21 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86. Nat Commun, 15, 2024
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7QNY
| The receptor binding domain of SARS-CoV-2 spike glycoprotein in complex with COVOX-58 and COVOX-158 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COVOX-158 heavy chain, COVOX-158 light chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2021-12-23 | 公開日 | 2022-01-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses. Cell, 185, 2022
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1BBT
| METHODS USED IN THE STRUCTURE DETERMINATION OF FOOT AND MOUTH DISEASE VIRUS | 分子名称: | FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1), FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP2), FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP3), ... | 著者 | Acharya, K.R, Fry, E.E, Logan, D.T, Stuart, D.I. | 登録日 | 1992-05-18 | 公開日 | 1994-01-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Methods used in the structure determination of foot-and-mouth disease virus. Acta Crystallogr.,Sect.A, 49, 1993
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7QNW
| The receptor binding domain of SARS-CoV-2 Omicron variant spike glycoprotein in complex with Beta-55 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Beta-55 heavy chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2021-12-23 | 公開日 | 2022-01-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses. Cell, 185, 2022
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7QNX
| The receptor binding domain of SARS-CoV-2 spike glycoprotein in complex with Beta-55 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-55 heavy chain, Beta-55 light chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2021-12-23 | 公開日 | 2022-01-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses. Cell, 185, 2022
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7NX6
| Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, COVOX-222 Fab Heavy chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D. | 登録日 | 2021-03-17 | 公開日 | 2021-04-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Antibody evasion by the P.1 strain of SARS-CoV-2. Cell, 184, 2021
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7NX7
| Crystal structure of the K417N mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CITRIC ACID, ... | 著者 | Zhou, D, Ren, J, Stuart, D. | 登録日 | 2021-03-17 | 公開日 | 2021-04-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Antibody evasion by the P.1 strain of SARS-CoV-2. Cell, 184, 2021
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7NXA
| Crystal structure of the receptor binding domain of SARS-CoV-2 B.1.351 variant Spike glycoprotein in complex with COVOX-222 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COVOX-222 Fab heavy chain, COVOX-222 Fab light chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D. | 登録日 | 2021-03-17 | 公開日 | 2021-04-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Antibody evasion by the P.1 strain of SARS-CoV-2. Cell, 184, 2021
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7NX8
| Crystal structure of the K417T mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CITRIC ACID, ... | 著者 | Zhou, D, Ren, J, Stuart, D. | 登録日 | 2021-03-17 | 公開日 | 2021-04-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Antibody evasion by the P.1 strain of SARS-CoV-2. Cell, 184, 2021
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7NXB
| Crystal structure of the receptor binding domain of SARS-CoV-2 P.1 variant Spike glycoprotein in complex with COVOX-222 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COVOX-222 Fab heavy chain, COVOX-222 Fab light chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D. | 登録日 | 2021-03-17 | 公開日 | 2021-04-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Antibody evasion by the P.1 strain of SARS-CoV-2. Cell, 184, 2021
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7NXC
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7NX9
| Crystal structure of the N501Y mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, COVOX-222 Fab heavy chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D. | 登録日 | 2021-03-17 | 公開日 | 2021-04-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Antibody evasion by the P.1 strain of SARS-CoV-2. Cell, 184, 2021
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4Q4F
| Crystal structure of LIMP-2 (space group C2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-beta-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Y, Ren, J, Padilla-Parra, S, Fry, L.E, Stuart, D.I. | 登録日 | 2014-04-14 | 公開日 | 2014-07-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Lysosome sorting of beta-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor. Nat Commun, 5, 2014
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4Q4B
| Crystal structure of LIMP-2 (space group C2221) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosome membrane protein 2, ... | 著者 | Zhao, Y, Ren, J, Padilla-Parra, S, Fry, L.E, Stuart, D.I. | 登録日 | 2014-04-14 | 公開日 | 2014-07-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Lysosome sorting of beta-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor. Nat Commun, 5, 2014
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5OYI
| FMDV A10 dissociated pentamer | 分子名称: | Genome polyprotein | 著者 | Kotecha, A, Malik, N, Stuart, D.I. | 登録日 | 2017-09-09 | 公開日 | 2017-09-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (8.2 Å) | 主引用文献 | Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation. PLoS Pathog., 13, 2017
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8CBD
| SARS-CoV-2 Delta-RBD complexed with BA.4/5-1 and EY6A Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BA.4/5-1 heavy chain, BA.4/5-1 light chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2023-01-25 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | 主引用文献 | Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection. Nat Commun, 15, 2024
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8CBF
| SARS-CoV-2 Delta-RBD complexed with Omi-42 and Beta-49 Fabs | 分子名称: | Beta-49 heavy chain, Beta-49 light chain, CHLORIDE ION, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2023-01-25 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection. Nat Commun, 15, 2024
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8CBE
| SARS-CoV-2 Delta-RBD complexed with BA.4/5-2 and Beta-49 Fabs | 分子名称: | BA.4/5-2 heavy chain, BA.4/5-2 light chain, Beta-49 heavy chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2023-01-25 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | 主引用文献 | Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection. Nat Commun, 15, 2024
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8CMA
| SARS-CoV-2 Delta-RBD complexed with BA.4/5-35 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BA.4/5-35 heavy chain, BA.4/5-35 light chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2023-02-18 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | 主引用文献 | Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection. Nat Commun, 15, 2024
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7ZRC
| OMI-38 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Omi-38 Fab Heavy Chain, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | 登録日 | 2022-05-04 | 公開日 | 2022-06-01 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Potent cross-reactive antibodies following Omicron breakthrough in vaccinees. Cell, 185, 2022
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7ZR9
| OMI-2 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE GLYCOPROTEIN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Omi-2 Fab heavy chain, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | 登録日 | 2022-05-03 | 公開日 | 2022-06-01 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Potent cross-reactive antibodies following Omicron breakthrough in vaccinees. Cell, 185, 2022
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