4Q4B

Crystal structure of LIMP-2 (space group C2221)

Summary for 4Q4B

Entry DOI	10.2210/pdb4q4b/pdb
Related	4Q4F
Descriptor	Lysosome membrane protein 2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	lysosomal targeting, beta-glucocerebrosidase, ci-mpr, er, endosome, lysosome, cell adhesion
Biological source	Homo sapiens (human)
Cellular location	Lysosome membrane; Multi-pass membrane protein: Q14108
Total number of polymer chains	1
Total formula weight	53194.66
Authors	Zhao, Y.,Ren, J.,Padilla-Parra, S.,Fry, L.E.,Stuart, D.I. (deposition date: 2014-04-14, release date: 2014-07-30, Last modification date: 2023-09-20)
Primary citation	Zhao, Y.,Ren, J.,Padilla-Parra, S.,Fry, E.E.,Stuart, D.I. Lysosome sorting of beta-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor. Nat Commun, 5:4321-4321, 2014 Cited by PubMed: 25027712 DOI: 10.1038/ncomms5321 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.82 Å)

Structure validation