8CMA

SARS-CoV-2 Delta-RBD complexed with BA.4/5-35 Fab

Summary for 8CMA

• Entry DOI: 10.2210/pdb8cma/pdb
• Related: 8CBD 8CBE 8CBF 8CII 8CIM 8CIN
• Descriptor: BA.4/5-35 heavy chain, Spike protein S1, BA.4/5-35 light chain, ... (4 entities in total)
• Functional Keywords: sars-cov-2, ba.4 mab, ba.5 mab, rbd, ba.4/5-1, ba.4/5-2, ba.4/5-5, beta-49, omi-42, ba.4/5-35, viral protein/immune system, viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 70351.71

Authors

Zhou, D.,Ren, J.,Stuart, D.I. (deposition date: 2023-02-18, release date: 2024-02-28, Last modification date: 2024-05-08)

• Primary citation: Liu, C.,Das, R.,Dijokaite-Guraliuc, A.,Zhou, D.,Mentzer, A.J.,Supasa, P.,Selvaraj, M.,Duyvesteyn, H.M.E.,Ritter, T.G.,Temperton, N.,Klenerman, P.,Dunachie, S.J.,Paterson, N.G.,Williams, M.A.,Hall, D.R.,Fry, E.E.,Mongkolsapaya, J.,Ren, J.,Stuart, D.I.,Screaton, G.R.; Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection.; Nat Commun, 15:3284-3284, 2024; PubMed: 38627386; DOI: 10.1038/s41467-024-47393-3

Experimental method

X-RAY DIFFRACTION (3.29 Å)