Crystal structure of LIMP-2 (space group C2)

Summary for 4Q4F

DescriptorLysosome membrane protein 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... (6 entities in total)
Functional Keywordslysosomal targeting, beta-glucocerebrosidase, ci-mpr, er, endosome, lysosome, cell adhesion
Biological sourceHomo sapiens (human)
Cellular locationLysosome membrane; Multi-pass membrane protein Q14108
Total number of polymer chains1
Total molecular weight53822.59
Zhao, Y.,Ren, J.,Padilla-Parra, S.,Fry, L.E.,Stuart, D.I. (deposition date: 2014-04-14, release date: 2014-07-30)
Primary citation
Zhao, Y.,Ren, J.,Padilla-Parra, S.,Fry, E.E.,Stuart, D.I.
Lysosome sorting of beta-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor.
Nat Commun, 5:4321-4321, 2014
PubMed: 25027712 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms5321
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26521.0%2.5%1.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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