7ZIR
 
 | | Cryo-EM structure of hnRNPDL amyloid fibrils | | 分子名称: | Heterogeneous nuclear ribonucleoprotein D-like | | 著者 | Garcia-Pardo, J, Chaves-Sanjuan, A, Bartolome-Nafria, A, Gil-Garcia, M, Visentin, C, Bolognesi, M, Ricagno, S, Ventura, S. | | 登録日 | 2022-04-08 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3.
Nat Commun, 14, 2023
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1YIO
 | | Crystallographic structure of response regulator StyR from Pseudomonas fluorescens | | 分子名称: | MAGNESIUM ION, MERCURY (II) ION, response regulatory protein | | 著者 | Milani, M, Leoni, L, Rampioni, G, Zennaro, E, Ascenzi, P, Bolognesi, M. | | 登録日 | 2005-01-12 | | 公開日 | 2005-09-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | An Active-like Structure in the Unphosphorylated StyR Response Regulator Suggests a Phosphorylation- Dependent Allosteric Activation Mechanism
STRUCTURE, 13, 2005
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3NA4
 | | D53P beta-2 microglobulin mutant | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Beta-2-microglobulin | | 著者 | Azinas, S, Ricagno, S, Bolognesi, M. | | 登録日 | 2010-06-01 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | D-strand perturbation and amyloid propensity in beta-2 microglobulin
Febs J., 278, 2011
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5OLU
 | | The crystal structure of a highly thermostable carboxyl esterase from Bacillus coagulans in complex with glycerol | | 分子名称: | ACETATE ION, Alpha/beta hydrolase family protein, CHLORIDE ION, ... | | 著者 | Gourlay, L.J, Nakhnoukh, C, Bolognesi, M. | | 登録日 | 2017-07-28 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A stereospecific carboxyl esterase from Bacillus coagulans hosting nonlipase activity within a lipase-like fold.
FEBS J., 285, 2018
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2HU2
 | | CTBP/BARS in ternary complex with NAD(H) and RRTGAPPAL peptide | | 分子名称: | 9-mer peptide from Zinc finger protein 217, C-terminal-binding protein 1, FORMIC ACID, ... | | 著者 | Nardini, M, Bolognesi, M, Quinlan, K.G.R, Verger, A, Francescato, P, Crossley, M. | | 登録日 | 2006-07-26 | | 公開日 | 2006-10-31 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Specific Recognition of ZNF217 and Other Zinc Finger Proteins at a Surface Groove of C-Terminal Binding Proteins
Mol.Cell.Biol., 26, 2006
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1ZN2
 | | Low Resolution Structure of Response Regulator StyR | | 分子名称: | MAGNESIUM ION, response regulatory protein | | 著者 | Milani, M, Leoni, L, Rampioni, G, Zennaro, E, Ascenzi, P, Bolognesi, M. | | 登録日 | 2005-05-11 | | 公開日 | 2005-09-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | An Active-like Structure in the Unphosphorylated StyR Response Regulator Suggests a Phosphorylation- Dependent Allosteric Activation Mechanism.
STRUCTURE, 13, 2005
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8A11
 | | Cryo-EM structure of the Human SHMT1-RNA complex | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, cytosolic | | 著者 | Spizzichino, S, Marabelli, C, Bharadwaj, A, Jakobi, A.J, Chaves-Sanjuan, A, Giardina, G, Bolognesi, M, Cutruzzola, F. | | 登録日 | 2022-05-30 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1.
Mol.Cell, 2024
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8OFI
 | | Ivabradine bound to HCN4 channel | | 分子名称: | Ivabradine, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | | 著者 | Saponaro, A, Chaves-Sanjuan, A, Sharifzadeh, A.S, Clarke, O.B, Marabelli, C, Bolognesi, M, Thiel, G, Moroni, A. | | 登録日 | 2023-03-15 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural determinants of ivabradine block of the open pore of HCN4.
Proc.Natl.Acad.Sci.USA, 121, 2024
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6I2Z
 | | Isolated globin domain of the Bordetella pertussis globin-coupled sensor | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Uncharacterized protein | | 著者 | Germani, F, De Schutter, A, Cuypers, B, Berghmans, H, Van Hauwaert, M.-L, Bruno, S, Mozzarelli, A, Moens, L, Van Doorslaer, S, Bolognesi, M, Pesce, A, Dewilde, S. | | 登録日 | 2018-11-02 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural and Functional Characterization of the Globin-Coupled Sensors ofAzotobacter vinelandiiandBordetella pertussis.
Antioxid.Redox Signal., 32, 2020
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1MOH
 | | FERRIC MONOMERIC HEMOGLOBIN I (HB I) | | 分子名称: | HYDROSULFURIC ACID, MONOMERIC HEMOGLOBIN I, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Rizzi, M, Wittenberg, J.B, Ascenzi, P, Bolognesi, M. | | 登録日 | 1996-02-27 | | 公開日 | 1996-08-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural bases for sulfide recognition in Lucina pectinata hemoglobin I.
J.Mol.Biol., 258, 1996
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2QRW
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1FCS
 | | CRYSTAL STRUCTURE OF A DISTAL SITE DOUBLE MUTANT OF SPERM WHALE MYOGLOBIN AT 1.6 ANGSTROMS RESOLUTION | | 分子名称: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | 著者 | Rizzi, M, Bolognesi, M, Coda, A, Cutruzzola, F, Travaglini Allocatelli, C, Brancaccio, A, Brunori, M. | | 登録日 | 1993-04-20 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of a distal site double mutant of sperm whale myoglobin at 1.6 A resolution.
FEBS Lett., 320, 1993
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2OXT
 | | Crystal structure of Meaban virus nucleoside-2'-O-methyltransferase | | 分子名称: | NUCLEOSIDE-2'-O-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE | | 著者 | Mastrangelo, E, Milani, M, Bollati, M, Bolognesi, M. | | 登録日 | 2007-02-21 | | 公開日 | 2007-05-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural bases for substrate recognition and activity in Meaban virus nucleoside-2'-O-methyltransferase
Protein Sci., 16, 2007
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1KR7
 | | Crystal structure of the nerve tissue mini-hemoglobin from the nemertean worm Cerebratulus lacteus | | 分子名称: | ACETATE ION, Neural globin, OXYGEN MOLECULE, ... | | 著者 | Pesce, A, Nardini, M, Dewilde, S, Geuens, E, Yamauchi, k, Ascenzi, P, Riggs, A.F, Moens, L, Bolognesi, M. | | 登録日 | 2002-01-09 | | 公開日 | 2002-05-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The 109 residue nerve tissue minihemoglobin from Cerebratulus lacteus highlights striking structural plasticity of the alpha-helical globin fold
Structure, 10, 2002
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7ZCE
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7ZCF
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5AB8
 | | High resolution X-ray structure of the N-terminal truncated form (residues 1-11) of Mycobacterium tuberculosis HbN | | 分子名称: | ACETATE ION, FORMIC ACID, GLYCEROL, ... | | 著者 | Pesce, A, Bustamante, J.P, Bidon-Chanal, A, Boechi, L, Estrin, D.A, Luque, F.J, Sebilo, A, Guertin, M, Bolognesi, M, Ascenzi, P, Nardini, M. | | 登録日 | 2015-08-04 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | The N-Terminal Pre-A Region of Mycobacterium Tuberculosis 2/2Hbn Promotes No-Dioxygenase Activity.
FEBS J., 283, 2016
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5CKA
 | | Human beta-2 microglobulin double mutant W60G-N83V | | 分子名称: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | | 登録日 | 2015-07-15 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
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5CKG
 | | Human beta-2 microglobulin mutant V85E | | 分子名称: | ACETATE ION, Beta-2-microglobulin, GLYCEROL | | 著者 | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | | 登録日 | 2015-07-15 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
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5CFH
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4THN
 | | THE CRYSTAL STRUCTURE OF ALPHA-THROMBIN-HIRUNORM IV COMPLEX REVEALS A NOVEL SPECIFICITY SITE RECOGNITION MODE. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN, HIRUNORM IV | | 著者 | Lombardi, A, De Simone, G, Nastri, F, Galdiero, S, Della Morte, R, Staiano, N, Pedone, C, Bolognesi, M, Pavone, V. | | 登録日 | 1998-09-18 | | 公開日 | 1999-06-15 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structure of alpha-thrombin-hirunorm IV complex reveals a novel specificity site recognition mode.
Protein Sci., 8, 1999
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5CSG
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5CSB
 | | The crystal structure of beta2-microglobulin D76N mutant at room temperature | | 分子名称: | Beta-2-microglobulin | | 著者 | de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S. | | 登録日 | 2015-07-23 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.719 Å) | | 主引用文献 | Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
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5CS7
 | | The crystal structure of wt beta2-microglobulin at room temperature | | 分子名称: | Beta-2-microglobulin | | 著者 | de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S. | | 登録日 | 2015-07-23 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
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2QEQ
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