7ZCE

SARS-CoV-2 Spike protein in complex with the single chain fragment scFv76

Summary for 7ZCE

• Entry DOI: 10.2210/pdb7zce/pdb
• EMDB information: 14628
• Descriptor: Spike glycoprotein,Fibritin, scFv76 single chain fragment, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: sars-cov-2, spike, single chain fragment, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 6
• Total formula weight: 522470.58

Authors

Chaves-Sanjuan, A.,Bolognesi, M. (deposition date: 2022-03-28, release date: 2022-10-12, Last modification date: 2023-02-08)

• Primary citation: Milazzo, F.M.,Chaves-Sanjuan, A.,Minenkova, O.,Santapaola, D.,Anastasi, A.M.,Battistuzzi, G.,Chiapparino, C.,Rosi, A.,Merlo Pich, E.,Albertoni, C.,Marra, E.,Luberto, L.,Viollet, C.,Spagnoli, L.G.,Riccio, A.,Rossi, A.,Santoro, M.G.,Ballabio, F.,Paissoni, C.,Camilloni, C.,Bolognesi, M.,De Santis, R.; Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery.; Mol.Ther., 31:362-373, 2022; PubMed: 36114671; DOI: 10.1016/j.ymthe.2022.09.010

Experimental method

ELECTRON MICROSCOPY (3.5 Å)