4THN
THE CRYSTAL STRUCTURE OF ALPHA-THROMBIN-HIRUNORM IV COMPLEX REVEALS A NOVEL SPECIFICITY SITE RECOGNITION MODE.
Summary for 4THN
Entry DOI | 10.2210/pdb4thn/pdb |
Descriptor | ALPHA-THROMBIN, HIRUNORM IV, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | complex (serine protease-inhibitor), thrombin synthetic inhibitors, antithrombotics, hirudin-like binding mode, hirunorms, thrombin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 37114.23 |
Authors | Lombardi, A.,De Simone, G.,Nastri, F.,Galdiero, S.,Della Morte, R.,Staiano, N.,Pedone, C.,Bolognesi, M.,Pavone, V. (deposition date: 1998-09-18, release date: 1999-06-15, Last modification date: 2023-08-09) |
Primary citation | Lombardi, A.,De Simone, G.,Nastri, F.,Galdiero, S.,Della Morte, R.,Staiano, N.,Pedone, C.,Bolognesi, M.,Pavone, V. The crystal structure of alpha-thrombin-hirunorm IV complex reveals a novel specificity site recognition mode. Protein Sci., 8:91-95, 1999 Cited by PubMed: 10210187PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report