2OSH
 
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7E1L
 | | Crystal structure of apo form PhlH | | 分子名称: | DUF1956 domain-containing protein | | 著者 | Zhang, N, Wu, J, He, Y.X, Ge, H. | | 登録日 | 2021-02-01 | | 公開日 | 2022-02-02 | | 最終更新日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular basis for coordinating secondary metabolite production by bacterial and plant signaling molecules.
J.Biol.Chem., 298, 2022
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7E1N
 | | Crystal structure of PhlH in complex with 2,4-diacetylphloroglucinol | | 分子名称: | 2,4-bis[(1R)-1-oxidanylethyl]benzene-1,3,5-triol, DUF1956 domain-containing protein | | 著者 | Zhang, N, Wu, J, He, Y.X, Ge, H. | | 登録日 | 2021-02-02 | | 公開日 | 2022-02-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular basis for coordinating secondary metabolite production by bacterial and plant signaling molecules.
J.Biol.Chem., 298, 2022
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1CEA
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5MSL
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3P97
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7F0N
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4B3N
 | | Crystal structure of rhesus TRIM5alpha PRY/SPRY domain | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MALTOSE-BINDING PERIPLASMIC PROTEIN, TRIPARTITE MOTIF-CONTAINING PROTEIN 5, ... | | 著者 | Yang, H, Ji, X, Zhao, Q, Xiong, Y. | | 登録日 | 2012-07-25 | | 公開日 | 2012-10-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural Insight Into HIV-1 Capsid Recognition by Rhesus Trim5Alpha
Proc.Natl.Acad.Sci.USA, 109, 2012
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3P8Z
 | | Dengue Methyltransferase bound to a SAM-based inhibitor | | 分子名称: | (S)-2-amino-4-(((2S,3S,4R,5R)-5-(6-(3-chlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylthio)butanoic acid, Non-structural protein 5, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Noble, C.G, Yap, L.J, Lescar, J. | | 登録日 | 2010-10-15 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Small molecule inhibitors that selectively block dengue virus methyltransferase
J.Biol.Chem., 286, 2011
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2X24
 | | bovine ACC2 CT domain in complex with inhibitor | | 分子名称: | ACETYL-COA CARBOXYLASE, TERT-BUTYL [(TRANS-4-{[({2-[4-(AMINOMETHYL)PHENYL]QUINOLIN-4-YL}CARBONYL)AMINO]METHYL}CYCLOHEXYL)METHYL]CARBAMATE | | 著者 | Oster, L, Folmer, R, Blaho, S, Wiberg, F, Hallberg, K. | | 登録日 | 2010-01-11 | | 公開日 | 2011-01-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Design of Small Molecule Inhibitors of Acetyl-Coa Carboxylase 1 and 2 Showing Reduction of Hepatic Malonyl-Coa Levels in Vivo in Obese Zucker Rats.
Bioorg.Med.Chem., 19, 2011
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7YI3
 | | Cryo-EM structure of Rpd3S in close-state Rpd3S-NCP complex | | 分子名称: | Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... | | 著者 | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | | 登録日 | 2022-07-14 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
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7YI2
 | | Cryo-EM structure of Rpd3S in loose-state Rpd3S-NCP complex | | 分子名称: | Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... | | 著者 | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | | 登録日 | 2022-07-14 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
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7YI1
 | | Cryo-EM structure of Eaf3 CHD bound to H3K36me3 nucleosome | | 分子名称: | Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ... | | 著者 | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | | 登録日 | 2022-07-14 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
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7YI0
 | | Cryo-EM structure of Rpd3S complex | | 分子名称: | Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... | | 著者 | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | | 登録日 | 2022-07-14 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
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3QSU
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1CEB
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4CZS
 | | Discovery of Glycomimetic Ligands via Genetically-encoded Library of Phage displaying Mannose-peptides | | 分子名称: | 2-hydroxyethyl alpha-D-mannopyranoside, CALCIUM ION, Concanavalin V, ... | | 著者 | Ng, S, Lin, E, Tjhung, K.F, Gerlits, O, Sood, A, Kasper, B, Deng, L, Kitov, P.I, Matochko, W.L, Paschal, B.M, Noren, C.J, Klassen, J, Mahal, L.K, Coates, L, Woods, R.J, Derda, R. | | 登録日 | 2014-04-22 | | 公開日 | 2015-04-22 | | 最終更新日 | 2022-12-07 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Genetically-Encoded Fragment-Based Discovery of Glycopeptide Ligands for Carbohydrate-Binding Proteins.
J.Am.Chem.Soc., 137, 2015
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7YI4
 | | Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in close state | | 分子名称: | Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ... | | 著者 | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | | 登録日 | 2022-07-14 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | | 主引用文献 | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
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7YI5
 | | Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in loose state | | 分子名称: | Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ... | | 著者 | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | | 登録日 | 2022-07-14 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | | 主引用文献 | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
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3A7N
 | | Crystal structure of uracil-DNA glycosylase from Mycobacterium tuberculosis | | 分子名称: | CITRATE ANION, Uracil-DNA glycosylase | | 著者 | Kaushal, P.S, Talawar, R.K, Varshney, U, Vijayan, M. | | 登録日 | 2009-09-29 | | 公開日 | 2010-08-11 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of uracil-DNA glycosylase from Mycobacterium tuberculosis: insights into interactions with ligands
Acta Crystallogr.,Sect.F, 66, 2010
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2ZHX
 | | Crystal structure of Uracil-DNA Glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor | | 分子名称: | Uracil-DNA glycosylase, Uracil-DNA glycosylase inhibitor | | 著者 | Kaushal, P.S, Talawar, R.K, Krishna, P.D.V, Varshney, U, Vijayan, M. | | 登録日 | 2008-02-11 | | 公開日 | 2008-05-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Unique features of the structure and interactions of mycobacterial uracil-DNA glycosylase: structure of a complex of the Mycobacterium tuberculosis enzyme in comparison with those from other sources
Acta Crystallogr.,Sect.D, 64, 2008
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2KOD
 | | A high-resolution NMR structure of the dimeric C-terminal domain of HIV-1 CA | | 分子名称: | HIV-1 CA C-terminal domain | | 著者 | Byeon, I.-J.L, Jung, J, Ahn, J, concel, J, Gronenborn, A.M. | | 登録日 | 2009-09-18 | | 公開日 | 2009-11-24 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function.
Cell(Cambridge,Mass.), 139, 2009
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4GAX
 | | Crystal Structure of an alpha-Bisabolol synthase mutant | | 分子名称: | Amorpha-4,11-diene synthase | | 著者 | Li, J, Peng, Z. | | 登録日 | 2012-07-26 | | 公開日 | 2013-03-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9948 Å) | | 主引用文献 | Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency.
Biochem.J., 451, 2013
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1GSQ
 | | THREE-DIMENSIONAL STRUCTURE, CATALYTIC PROPERTIES AND EVOLUTION OF A SIGMA CLASS GLUTATHIONE TRANSFERASE FROM SQUID, A PROGENITOR OF THE LENS-CRYSTALLINS OF CEPHALOPODS | | 分子名称: | GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE | | 著者 | Ji, X, Rosenvinge, E.C.V, Armstrong, R.N, Gilliland, G.L. | | 登録日 | 1995-01-09 | | 公開日 | 1995-06-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods.
Biochemistry, 34, 1995
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6D1E
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