7VUM
 
 | | Crystal structure of SSB complexed with que | | Descriptor: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, Single-stranded DNA-binding protein | | Authors: | Lin, E.S, Huang, Y.H, Huang, C.Y. | | Deposit date: | 2021-11-03 | | Release date: | 2022-03-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.319 Å) | | Cite: | A Complexed Crystal Structure of a Single-Stranded DNA-Binding Protein with Quercetin and the Structural Basis of Flavonol Inhibition Specificity.
Int J Mol Sci, 23, 2022
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8HFD
 | | Crystal structure of allantoinase from E. coli BL21 | | Descriptor: | Allantoinase, DI(HYDROXYETHYL)ETHER, ZINC ION | | Authors: | Lin, E.S, Huang, H.Y, Yang, P.C, Liu, H.W, Huang, C.Y. | | Deposit date: | 2022-11-10 | | Release date: | 2023-10-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Crystal Structure of Allantoinase from Escherichia coli BL21: A Molecular Insight into a Role of the Active Site Loops in Catalysis.
Molecules, 28, 2023
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7F2N
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7DEP
 | | S. aureus SsbB with 5-FU | | Descriptor: | 5-FLUOROURACIL, Single-stranded DNA-binding protein | | Authors: | Lin, E.S, Huang, Y.H, Huang, C.Y. | | Deposit date: | 2020-11-04 | | Release date: | 2020-12-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.094 Å) | | Cite: | Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein
Biochem.Biophys.Res.Commun., 534, 2020
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7D8J
 | | S. aureus SsbB with 5-FU | | Descriptor: | 5-FLUOROURACIL, Single-stranded DNA-binding protein | | Authors: | Lin, E.S, Huang, Y.H, Huang, C.Y. | | Deposit date: | 2020-10-08 | | Release date: | 2020-12-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein
Biochem.Biophys.Res.Commun., 534, 2020
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7VGN
 | | Crystal structure of CmnC | | Descriptor: | 2-OXOGLUTARIC ACID, ACETATE ION, CmnC, ... | | Authors: | Huang, S.J, Hsiao, Y.H, Lin, E.C, Lee, Y.C, Zheng, Y.Z, Chang, C.Y. | | Deposit date: | 2021-09-17 | | Release date: | 2022-09-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7VGL
 | | Crystal structure of CmnC | | Descriptor: | ACETATE ION, CmnC | | Authors: | Hsiao, Y.H, Huang, S.J, Lin, E.C, Lee, Y.C, Zheng, Y.Z, Chang, C.Y. | | Deposit date: | 2021-09-17 | | Release date: | 2022-09-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7Y0G
 | | Crystal structure of anti-mPEG h15-2b Fab | | Descriptor: | 15-2b heavy chain, 15-2b light chain, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL | | Authors: | Chang, C.Y, Nguyen, T.M.T, Lin, E.C, Su, Y.C. | | Deposit date: | 2022-06-05 | | Release date: | 2022-08-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structural determination of an antibody that specifically recognizes polyethylene glycol with a terminal methoxy group
Commun Chem, 5, 2022
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4CZS
 | | Discovery of Glycomimetic Ligands via Genetically-encoded Library of Phage displaying Mannose-peptides | | Descriptor: | 2-hydroxyethyl alpha-D-mannopyranoside, CALCIUM ION, Concanavalin V, ... | | Authors: | Ng, S, Lin, E, Tjhung, K.F, Gerlits, O, Sood, A, Kasper, B, Deng, L, Kitov, P.I, Matochko, W.L, Paschal, B.M, Noren, C.J, Klassen, J, Mahal, L.K, Coates, L, Woods, R.J, Derda, R. | | Deposit date: | 2014-04-22 | | Release date: | 2015-04-22 | | Last modified: | 2022-12-07 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Genetically-Encoded Fragment-Based Discovery of Glycopeptide Ligands for Carbohydrate-Binding Proteins.
J.Am.Chem.Soc., 137, 2015
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7V5L
 | | Crystal structure of human bleomycin hydrolase | | Descriptor: | Bleomycin hydrolase | | Authors: | Chang, C.Y, Zheng, Y.Z, Huang, S.J, Wang, Y.L, Toh, S.I, Lin, E.C. | | Deposit date: | 2021-08-17 | | Release date: | 2022-06-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease.
Chembiochem, 23, 2022
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7Y5I
 | | Crystal structure of CmnC in complex with L-homoarginine | | Descriptor: | ARGININE, CmnC, FE (III) ION, ... | | Authors: | Hsiao, Y.H, Huang, S.J, Lin, E.C, Lee, Y.C, Chang, C.Y. | | Deposit date: | 2022-06-17 | | Release date: | 2023-07-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7Y5P
 | | Crystal structure of CmnC in complex with L-arginine and alpha-KG | | Descriptor: | 2-OXOGLUTARIC ACID, ARGININE, CmnC, ... | | Authors: | Hsiao, Y.H, Huang, S.J, Lin, E.C, Lee, Y.C, Chang, C.Y. | | Deposit date: | 2022-06-17 | | Release date: | 2023-07-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7Y5F
 | | Crystal structure of CmnC in complex with L-homoarginine | | Descriptor: | CmnC, FE (III) ION, L(+)-TARTARIC ACID, ... | | Authors: | Hsiao, Y.H, Huang, S.J, Lin, E.C, Lee, Y.C, Chang, C.Y. | | Deposit date: | 2022-06-17 | | Release date: | 2023-07-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7YHE
 | | Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG | | Descriptor: | 2-OXOGLUTARIC ACID, CmnC, FE (III) ION, ... | | Authors: | Huang, S.J, Hsiao, Y.H, Lin, E.C, Hsiao, P.Y, Chang, C.Y. | | Deposit date: | 2022-07-13 | | Release date: | 2023-07-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7YW9
 | | Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG | | Descriptor: | ACETATE ION, CmnC, D-ARGININE, ... | | Authors: | Huang, S.J, Hsiao, Y.H, Lin, E.C, Hsiao, P.Y, Chang, C.Y. | | Deposit date: | 2022-08-22 | | Release date: | 2023-08-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7E3U
 | | Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-AU | | Descriptor: | 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, D-hydantoinase/dihydropyrimidinase, ZINC ION | | Authors: | Yang, Y.C, Luo, R.H, Huang, Y.H, Huang, C.Y, Lin, E.S. | | Deposit date: | 2021-02-09 | | Release date: | 2022-02-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.159 Å) | | Cite: | Molecular Insights into How the Dimetal Center in Dihydropyrimidinase Can Bind the Thymine Antagonist 5-Aminouracil: A Different Binding Mode from the Anticancer Drug 5-Fluorouracil.
Bioinorg Chem Appl, 2022, 2022
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2N28
 | | Solid-state NMR structure of Vpu | | Descriptor: | Protein Vpu | | Authors: | Zhang, H, Lin, E.C, Tian, Y, Das, B.B, Opella, S.J. | | Deposit date: | 2015-05-01 | | Release date: | 2015-09-30 | | Last modified: | 2015-10-14 | | Method: | SOLID-STATE NMR | | Cite: | Structural determination of virus protein U from HIV-1 by NMR in membrane environments.
Biochim.Biophys.Acta, 1848, 2015
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2N29
 | | Solution-state NMR structure of Vpu cytoplasmic domain | | Descriptor: | Protein Vpu | | Authors: | Zhang, H, Lin, E.C, Tian, Y, Das, B.B, Opella, S.J. | | Deposit date: | 2015-05-01 | | Release date: | 2015-09-30 | | Last modified: | 2015-10-14 | | Method: | SOLUTION NMR | | Cite: | Structural determination of virus protein U from HIV-1 by NMR in membrane environments.
Biochim.Biophys.Acta, 1848, 2015
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7V5S
 | | Crystal structure of human bleomycin hydrolase C73A mutant | | Descriptor: | Bleomycin hydrolase, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL | | Authors: | Chang, C.Y, Zheng, Y.Z, Huang, S.J, Wang, Y.L, Toh, S.I, Lin, E.C. | | Deposit date: | 2021-08-18 | | Release date: | 2022-06-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.02 Å) | | Cite: | The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease.
Chembiochem, 23, 2022
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7V5T
 | | Crystal structure of human bleomycin hydrolase C73S mutant | | Descriptor: | Bleomycin hydrolase | | Authors: | Chang, C.Y, Zheng, Y.Z, Huang, S.J, Wang, Y.L, Toh, S.I, Lin, E.C. | | Deposit date: | 2021-08-18 | | Release date: | 2022-06-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease.
Chembiochem, 23, 2022
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7XF9
 | | Crystal structure of human bleomycin hydrolase H372A mutant | | Descriptor: | Bleomycin hydrolase | | Authors: | Chang, C.Y, Zheng, Y.Z, Huang, S.J, Wang, Y.L, Toh, S.I, Lin, E.C. | | Deposit date: | 2022-04-01 | | Release date: | 2022-06-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease.
Chembiochem, 23, 2022
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7YM1
 | | Structure of SsbA protein in complex with the anticancer drug 5-fluorouracil | | Descriptor: | 5-FLUOROURACIL, GLYCEROL, Single-stranded DNA-binding protein | | Authors: | Huang, Y.H, Yang, P.C, Chiang, W.Y, Lin, E.S, Huang, C.Y. | | Deposit date: | 2022-07-27 | | Release date: | 2023-08-02 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Crystal Structure of DNA Replication Protein SsbA Complexed with the Anticancer Drug 5-Fluorouracil.
Int J Mol Sci, 24, 2023
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